The Big & Dandy 25C-NBOMe Thread (part 2) ver. "My skin feels like lightning"

[jason7]

It makes me feel like I have a stitch, like a poisoning of my liver or something.
And the inside of my legs hurts also.
I get the same with 25i, it feels so unhealthy.
And my brain always feel so fried.
Very fun but not very deep or spiritual.


Did 1.8mg 25c - 40min buccal last night

Come up was rough, almost puked.
Grasped the walls and held on tight as all the noises started reverbing and splitting apart.

Visually, fractals everywhere.
Everything waving around.

Mentally, really clear headspace.
So clear.

Talked to a police officer on it, she searched my bag and shit. It was so fucking intense.
But my insides are in considerable pain, I wish it would go away already.

Got that right, bruh. All of the phenethylamines derived from the 2,4,5 substitutions make me feel poisoned. They are all rather crude 5-HT receptor agonists which cause a range of unpleasant effects in addition to the psychedelic ones. I have a bunch of them and they all are completely undesirable to me because of the unpleasant side effects. I have read in the TCB-2 thread that it doesn't cause nausea at all and only minor shakes in the hands. No vasoconstriction was mentioned either. Granted it was only one person's account, the compound being still so rare, but it sounded like the fact that it is not a regular amine has cut out most if not all of the unpleasantness. His description also indicated that there was possible CNS stimulation like LSD, which is lacking in all regular phenethylamines. I think the only two usable RC psychs are probably TCB-2 and jimscaline, both having the amine functions replaced by other structures which make them fit the 5-HT receptors much more accurately. Although the NBOMEs are cheap and readily available, I have zero interest in ever using them again. Nausea and full body shakes and no euphoric stimulation whatsoever is not an attractive combination.

 

[cryptix420]

Got that right, bruh. All of the phenethylamines derived from the 2,4,5 substitutions make me feel poisoned. They are all rather crude 5-HT receptor agonists which cause a range of unpleasant effects in addition to the psychedelic ones. I have a bunch of them and they all are completely undesirable to me because of the unpleasant side effects. I have read in the TCB-2 thread that it doesn't cause nausea at all and only minor shakes in the hands. No vasoconstriction was mentioned either. Granted it was only one person's account, the compound being still so rare, but it sounded like the fact that it is not a regular amine has cut out most if not all of the unpleasantness. His description also indicated that there was possible CNS stimulation like LSD, which is lacking in all regular phenethylamines. I think the only two usable RC psychs are probably TCB-2 and jimscaline, both having the amine functions replaced by other structures which make them fit the 5-HT receptors much more accurately. Although the NBOMEs are cheap and readily available, I have zero interest in ever using them again. Nausea and full body shakes and no euphoric stimulation whatsoever is not an attractive combination.

Seconded. Give me good ol' lucy anyday.

 

[IamMe90]

Got that right, bruh. All of the phenethylamines derived from the 2,4,5 substitutions make me feel poisoned. They are all rather crude 5-HT receptor agonists which cause a range of unpleasant effects in addition to the psychedelic ones. I have a bunch of them and they all are completely undesirable to me because of the unpleasant side effects. I have read in the TCB-2 thread that it doesn't cause nausea at all and only minor shakes in the hands. No vasoconstriction was mentioned either. Granted it was only one person's account, the compound being still so rare, but it sounded like the fact that it is not a regular amine has cut out most if not all of the unpleasantness. His description also indicated that there was possible CNS stimulation like LSD, which is lacking in all regular phenethylamines. I think the only two usable RC psychs are probably TCB-2 and jimscaline, both having the amine functions replaced by other structures which make them fit the 5-HT receptors much more accurately. Although the NBOMEs are cheap and readily available, I have zero interest in ever using them again. Nausea and full body shakes and no euphoric stimulation whatsoever is not an attractive combination.

I'm fairly sure that phens have CNS stimulation, as do virtually all psychedelics... but i could be wrong. i'd be interested in hearing where you got this from.

 

[trilogique]

yeah I'd definitely take LSD over this any day simply because of the risks (I've never had any nausea or body shakes though). I have a bunch of 25c blotters and all this talk about OD and people in the hospital is freaking me out. I really want to slowly work my way up to an intense trip, but I really don't want to risk physical danger. so far I've done 600ug and 900ug. next time I'm cranking it up to 1.2mg but I'm scared of going higher than that even though I know 1mg buccally is different from insufflation etc.

EDIT: would it be alright to take 900ug then when I start coming down take 900ug more? would this bring me back to plateau or just extend the comedown by hours? or would this be physically dangerous? I can't find much info on redosing and I really want to extend my trip tonight because I have all of tomorrow off.

 

[zn13bt]

It'll extend the comedown, but it won't bring the trip back. Redosing on NBOMes doesn't really work well unless you do it within ~1 hour of the first dose. Better to take your entire dose all at once.

 

[Jesusgreen]

Gave 1.2mg of this a go recently, glad I didn't go for 2.2mg in the end as my BP went fairly up from normal at 1.2mg and also the come up was a little on the intense side. Ironically once I peaked it felt a lot milder than the come up itself despite actually being stronger - I think a few factors came into play there, one simply being that the NBOMes do have particularly intense come ups, the other being that the sun had just risen and I tend to find the NBOMe visuals less distracting in daylight.

Overall a rough and quite scary at times come up, but the 6-6.5 hours after I came up were very blissful, reminiscent of 2C-B in a lot of ways. Very chilled out and enjoyable, and one thing I noticed in particular was I kept getting the giggles throughout the trip - now I've heard so many stories about people getting them on any and every psychedelic but I've only really had them once or twice before on 2C-E really. On 25C though the entire trip everything kept setting me off laughing (after the come up anyway).

The overall peak with 1.2mg wasn't quite as intense as I'd been hoping for, but due to not wanting a scarier come up and even higher BP I'm fairly sure 2.2mg would have been way too much. I'd consider going to 1.4-1.5mg or so in the future coupled with weed to keep my BP down, but otherwise it seems I'd stick to the 1-1.2mg range.

One good thing is because I didn't take 2.2mg and just 1.2mg, I still have another 1mg blotter of the stuff left to take some time in the future. I'm looking forward to that, as this was a very pleasant warm drug.

 

[Survived Abortion]

Now imagine what that would have been like without tolerance of recent psychedelic/empathogen use. What ROA did you use? I also found the come up to be intense. It was like being floored with G-force.

I'm not sure exactly where you're getting this from? I haven't read very many reports at all of people getting their "asses kicked" at doses below 1mg taken buccally. I agree that nasally going to 1mg is too much. But from the vast majority of experience reports I've read in these threads and through my own and friends' experiences, 1mg has been a pretty standard, somewhat light trip. Most people seem to be taking doses in the 1-1.5mg range buccally, and that doesn't seem unreasonable to me at all.

I'm trying to look out for those with the weakest tolerance to such compounds, people like myself who find sub milligram doses taken sublingually/bucally to be very strong. If I had taken the advice to jump in at 1.5mg sublingually/bucally on my first try I would have been in for a very painful surprise. And I can quite sensibly extrapolate from that that there are others like me too.

Just what on earth is the point of recommending new users to a dose - of an already proven dangerous chemical - which is at the upper range of 'strong' for many, and probably scarily overwhelming to others with high sensitivity. Don't you think it's more sensible to usher people in to the low end of the dosing spectrum so that they can find their feet first, instead of being blasted at Mach 10 into a rocket launch of psychedelia and body-load they weren't expecting.

You and your friends may be able to tolerate such doses, but you and your friends are not representative of all human beings. I'm looking out for those of us who aren't dosing psychedelics every week and don't have naturally large tolerances to these chems.

As you can see, Jesusgreen has just posted about a "rough and quite scary at times come up" from 1.2mg, and that was with tolerance from using loads of other chems recently.

I find it astonishing that there was so much controversy over specific drug recommendations in that recent sticky questioning the "no recommendations" rule, when it seems perfectly acceptable for anybody to come on here and imply, if not outright recommend, their own personal doses of compounds, even when those doses are clearly in excess of what some people are finding to be heavy.

yeah I'd definitely take LSD over this any day simply because of the risks (I've never had any nausea or body shakes though). I have a bunch of 25c blotters and all this talk about OD and people in the hospital is freaking me out. I really want to slowly work my way up to an intense trip, but I really don't want to risk physical danger. so far I've done 600ug and 900ug. next time I'm cranking it up to 1.2mg but I'm scared of going higher than that even though I know 1mg buccally is different from insufflation etc.

So long as you're working your doses up mindfully like that, you're fine. It's those who are jumping in at the deep end who are in for trouble if it turns out that their guess at a good dose was wrong.

 

[sn23]

I wholeheartedly agree with you Survived Abortion.

These compounds are definitely on the physically dangerous side of psychedelic drugs' spectrum, perhaps akin to Bromo-Dragonfly, plus individual sensitivities seem to be all over the place. I think it's absolutely not justifiable to recommend 'common' dosages of these substances on a harm reduction forum. Individually titrating up to an active dose is the only reasonable way to treat NBOMes. Limited supply or wanting to 'jump in head first' or whatever are bad excuses to risk your health/life. Which is a very real possibility.

 

[Ismene]

His description also indicated that there was possible CNS stimulation like LSD, which is lacking in all regular phenethylamines.

You don't think mescaline stimulates your CNS?

 

[Jesusgreen]

It's worth noting I'm agreed with SA here that jumping in right at 1.5mg would be a bad idea. The only reason I suggested the 1-1.5mg range to someone was because that person claimed to have previously taken around 10mg - so they would not be jumping in at the deep end by taking such a dose.

That said, having tried 1.2mg I can see why there's a lot of controversy going on about the dosages. I think a lot of people are disappointed by the intensity of the peak itself and want to go higher - but I'm not quite sure that's safe.

With 1.2mg, the come up was intense, in a way that seemed to be building up uncontrollably - and left me thinking I'd taken way too much - my main fear was the blotter I took was 1" x 1" in size, and I thought what if my dealer had given me 4 blotters stuck together by mistake. After the come up though, the strength was nowhere even close to what I was looking for, and had I not had the come up to go on, I could easily have seen taking 2-2.5mg+ as a good idea. The actual trip from 1.2mg was not all that intense - I'm sure tolerance played a part in my case but I've heard others say the same.

However, you think that'd mean I'd be suggesting we up the dose higher, but I wouldn't suggest that - because as I noted in my last post, during the come up my BP went pretty high. 138/105 I think was the highest actual reading I got, with my normal blood pressure being 120/70, and even stimulant binges rarely pushing it past 130/95. This isn't a dangerous level, but it certainly is a worrying one and makes me want to urge caution to anyone considering pushing the dose higher.

I definitely wouldn't go combining this with other substances that raise your blood pressure unless the dose of both substances is on the low side.

 

[Ondine]

Seeing the 25c on tabs is most common for me; in fact, that's the only way I've taken it. I've never had what I would call a distinctive experience on it, though. Do you guys think sublingual via tab is a poor RoA? Seems to me that those of you insufflating and using the pure powder sublingually are having better experiences than I did.

 

[Jesusgreen]

Buccal > Sublingual with these imo. If you place the tab on your upper gum and keep it firmly sealed below your lip then little of your saliva will cover it so you're at less risk of losing material when you swallow your saliva. If you place it under your tongue it is sitting in your saliva the entire time and so unless you can avoid swallowing your saliva the entire time then there's probably a fair bit going to waste.

The time you hold them in your mouth is paramount too. I'd recommend at least 50-60 minutes if you want the full experience. Since these substances are not orally active at any reasonable dose, swallowing the tabs after 10-15 minutes when they still taste strongly of the substance is letting a LOT of material go to waste.

One other thing worth mentioning is that of course when it's on tabs you're just relying on your dealer's word for the dosage. Now of course, powder can be cut, but if you obtain 20mg of 25x-NBOMe powder from a reliable source you can trust not to cut it, and you measure out 1mg - you can be pretty sure that's 1mg, while if your dealer tells you that your tab is 1mg, you 're really just blindly going on his word, and even if he's reliable that's not to say the guy up the chain is.

 

[Survived Abortion]

I wholeheartedly agree with you Survived Abortion.

These compounds are definitely on the physically dangerous side of psychedelic drugs' spectrum, perhaps akin to Bromo-Dragonfly, plus individual sensitivities seem to be all over the place. I think it's absolutely not justifiable to recommend 'common' dosages of these substances on a harm reduction forum. Individually titrating up to an active dose is the only reasonable way to treat NBOMes. Limited supply or wanting to 'jump in head first' or whatever are bad excuses to risk your health/life. Which is a very real possibility.

Thanks for the support. I think that's a very fair comparison with Bromo-Dragonfly too; the NBOMes need to be treated with a similar approach of cautiousness. The dose-response curve is too steep and the 'therapeutic margin' too slim to be nonchalant about it. Individual titration is definitely the way to go with these compounds.

 

[lysergication]

I've tried various 2C, 2C-B included and I'd order more of 25C when mine is out because I found the visuals to be quite special and different...the head space too, it's more energetic and subtil than 2C-B. If the come up was more gradual when insufflated or the oral route effective, this would be a super winner, IMO.

 

[kidklmx]

I like 25c a lot for the exact reasons you were looking at it, the visuals are pretty good and it's euphoria can reach levels I have been unable to get to on even MDxx. Love it as a party-drug.

I think the bad (besides vaconstriction/shakes, which I both have from time to time, hardly worrisome though) on NBOMe's is coming from unevenly laid blotter. There's one friend of mine who reacts more heavily to this than the rest, but I put that down on his brain being fucked up. I mean, his mom is bipolar; schizophrenic and manically depressed. He gets delirious fast, even when he has something as simple as the flu. Not someone who should do psychedelics, I know, but if he's gonna do it anyway I'd rather be close to him to guide through it. All my other friends have reacted like they should.

EDIT: Haven't tried plugging (that's next on the list), but it's been said to be the ROA to go with.

 

[lysergication]

I'd be also interested to read about this roa

I found this and this

 

[TryptamineBunny]

I have found the 25C come-up to be very gentle at doses up to 700ug nasally administered. The trip just gently descends over an hour. It is the most unnoticable come-up I have ever experienced.

My experience to date has led me to believe that the physical euphoria of this substance is most present between about 350 to 600ug. A kind of happy confusion seems to dominate at higher doses. I have heard reports of literal face melting visuals at doses over 1000ug, but no euphoria.

My current estimate of maximum euphoric sweetspot is at 550ug.

 

[IamMe90]

700ug nasal is going to be a rough, nasty come up for most people. If you are worried about the physical side effects and are prone to them in other chemicals, do NOT take this chemical nasally, you've been forewarned.

The only time I have had good experience with nasal 25c (as someone who is very prone to body load) was taking a very small adjunct dose on a weak DOM trip. The trip wasn't going where I wanted intensity wise, so I took 200ug nasally for a little boost and it gave me massive visuals and crazy effects with no noticeable physical side effects at all.

 

[mozokev]

For me, 25c is very easy on the body, although I have only taken it buccally in doses up to 800ug. IME, the ROAs with shorter comeups also produce more negative bodily side effects

 

[Soul137]

So I finally got a chance to try 25C and I think i should drop my knowledge on y'all.

Background info:
I weighed out 12mg of 25C-NBOMe HCl on my 1mg scale but I will say my scale is no longer perfectly precise, especially when total weight is under 20mg, so all of the numbers I'm using could be off by 25% on either side. I then dissolved the 12mg in 10ml of 20% ethanol for a concentration 12mg/ml. (It took a good bit of stirring to dissolve) I then put my 10ml of solution in a nasal spray bottle that averaged .13ml/spray. This makes for 156ug/spray (unless of course my scale was off in which case, each spray might contain 200ug, but I will assume the sprays are 150ug to be conservative)

Dose timeline:
t=0:00 One small spray administered. The spray bottle was not cooperating, so this spray was likely not more than 75ug.
t+0:10 spray bottle functional. One full spray administered.
t+0:15 feeling good. Deep hearty laughs.
t+0:30 another full spray up the nose
t+0:43 some bruxism noted. some visuals appearing.
t+0:55 I feel shaky and stimulated. I have some the slimy saliva build up in my throat that is so idiosyncratic of 2C's.
t+1:00 levelled out a bit. pleasant intoxication. I say intoxication because it was a little like being tipsy while tripping. I was a bit disinhibited and social feeling. I had a lot to say about everything. I decided to take one more spray as I was at ++ and I wanted to get a real feel for this substance. This brought my total dose to around 500ug
t+1:30 visuals starting to become much more apparent. Melting and morphing. Colors are bright. Everything is very vivid when I pay attention but I can easily sort of space out and drift away... then snap... back to reality. I am once again kind of shaky and stimulated. It seems that about 20-30 minutes after each spray I would be dealing with a body load. and then by about 50 minutes after the spray, the trip would level out again and the body load would go away.
t+2:10 I notice some pretty fantastic kalaidascopic CEV's. Very vivid and colorful. flowering out from the center and rippling like an iTunes visualizers. +++ achieved. But not by much.
t+3:00 Seems to be past the plateau. Visuals are still very present but they are no longer in my face. My mood seemed very good. I was laughing lightheartedly and frequently. I felt calm and social yet still very high and very silly. My friend and I seem to be enthralled by the absurd. We laugh whenever something random happens.
t+5:00 pretty baseline. still kind of stimulated though. not in an uncomfortable way. But sleep would no doubt have been impossible at this point.

Extensions and commentary:
My friend and I both concluded that we like 25C a lot. and contrary to popular opinion, I think 25C felt VERY safe. the come up was stimulating but It felt less toxic than most phenethylamines. This chem seems light hearted and fun for the most part, but it seems to have a power to it that may be revealed at a higher dose.
On another not I think it is really cool to be able to spray some shit in your nose and then over the next hour you slide comfortably into psychedelia. It feels even easier than swallowing a pill. I think these sprays have a future as street drugs especially since it is so easy to dose over time to ease yourself into your trip. Not only that but this drug is euphoric AND colorful and therefor would probably do quite well in a rave setting. I can imagine in the future, people doing sprays of 25c in the crowd at a concert, the way they do bumps of K nowadays.

Conclusion: I think 25C is a big advance in recreational psychedelics. 25C has a lot of things, that I, as a drug user, want in my psychedelic experience and I think that others will feel the same way. If this stuff is proven to have a therapeutic index similar to, or wider than the 2C's, I can see it becoming VERY popular.