The Big & Dandy 25C-NBOMe Thread (part 2) ver. "My skin feels like lightning"

[klondike_bar]

some quick FAQ

Solubility In Water: ~8mg/mL at 20C , ~15mg/mL at 50C
Solubility in 75% EtOH: ~30mg/mL at 20C , ~50mg/mL at 50C

Dose: low = 300-450ug midrange = 500-650ug high = 700-900ug

 

[pharmakos]

i've been pondering making an NBOMe nasal spray. normal nasal spray (saline) is antiseptic because of its salt content. i don't believe that EtOH is necessary for an NBOMe nasal spray, as long as you can get your NBOMe to dissolve in your saline.

 

[Transform]

I would say 10% is plenty. I have some dissolved in vodka with a concentration requiring 0.4mls to be insufflated. It is absolutely horrendous and I would not do it without allowing some to evaporate first. Even then it's horrible.

 

[MDMAPhreak]

25C, Weeks of Thoughts and Questions

Hello everyone in the Psychadelic forum! I'm not necessarily new to BL (been researching and reading on this site for close to a decade now, since a very young age) but I'm new to being a member. This is probably the forum I'll be spending most of my time in as psychadelics both synthetic and natural are my forte and substances of choice.

The nature of this thread is to express some of my experience with 2C-C-NBOMe (25C) and ask a few questions about the molecule and use of the molecule itself. I'd really like to see if anybody has pushed an experience with 25C to the 2mg mark yet? Me and a close buddy did recently after much trial with this gem of a substance beforehand and are in the process of writing up a trip report for both here and Erowid on the night.

Without going into too much detail (I'll save that for the report later, soon to come) I'd say that the overall experience was still surprisingly clean. What I did come away with was the seemingness that there's really no point to pushing this molecule past about the 800ug mark. It wasn't that it turned negative on me in any way, just became a little wasteful, sort of like say taking over 1mg of LSD but less than 3mg. Admittedly it could have been the manner in which we dosed (we pushed it a little bit, redosed twice in the night to reach the 2mg mark without previously deciding to do that much that night) but I strongly feel like there's a plateau you hit near the 1mg mark with 25C that you would have to take 4 or 5mg to surpass which I'm not very interested in doing.

I'm very interested in hearing if anybody has come close to the 2mg mark in a single experience with this substance and if they have any of the same sentiments I do about it. The only noted difference between 2mg and 1mg was a more intense body euphoria mimicking that of MDxx's surprisingly well and some increase in visuals. I would note that this was a diluted liquid form used intranasally of known potency ~200ug/0.1mL.

The more I research and the more times I dose this NBOMe the more confident I become in its safety. I understand that it is an RC and very little to no studies have been done on it as of yet but the science seems pretty sound to me. Create a class of molecules that lowers the potentiated dose of a molecule considerably (thus less of a substance in your body), and have these molecules target a single receptor for agonization instead of multiple receptors for less flooding of neuro active chemicals in the brain thus leading it to be less neurotoxic. Or at least that's how it seems to me, I don't claim to have a degree in biochem or OChem or something similar though so I can't say that for certain. If anybody can offer on a basic chemistry level some ideas or thoughts on this I'd be interested in what you have to say. I don't want to tell my friends they're using something completely safe if they're not but with the lack of a psychadelic hangover the next day and the cleanliness of the trips I've had with this molecule I'd very much like to know if my basic logic makes sense to someone with a more specialized background or more experience academically in this area.

I'm happy to call myself a member of this great community and look forward to plenty of both fun and insightful conversation for years to come with y'all!

 

[Jesusgreen]

kyuss \m/

that is all

Just remember these aren't social threads ! Let's keep it that way please. Though yes, Kyuss are rather awesome. It's been ages since I've heard them, time for a listen methinks. :D (Pro-tip: We sort of allow social chatter if it's in a similar format to my post - if you're going to make a passing off-topic comment it's fine as long as the majority of the rest of the post is on-topic, and it's not just filler content.)

Anyway back on topic, does 25C-NBOMe leave a taste-associated bodyload after you've been chewing the tab for a good amount of time? Both times I've taken 25I-NBOMe the aftertaste in my mouth led to a weird bodyload for the first hour or two of the trip, which could only be remedied by food, drink, or other drugs. I've heard 25C is a lot more friendly than 25I and if this is the case I'd expect there to be less of any sort of bodyload too, but as it was mostly taste-associated I'm not sure. Any comments?

 

[demon cleaner]

Ah now we're talking useful

I'm thinking of using 70% pharmacy grade alcohol put about 20% the rest being demineralized water. I fear that vodka would be to thick and theres sugar also in vodka.
Im going to try out without the 25 first. If you've insufflated 4FA, you can snort anything haha

 

[pharmakos]

i really don't think that alcohol is necessary for a nasal solution. when i get around to it i'm going to use store bought saline nasal spray. saline is antibacterial, plus its intended to be shot up your nose anyway. =p

my only concern is whether or not it will dissolve. i think it will, though.

 

[Lombergerh]

What i really interested in - smoking is it possible? Dosage?
Can i just dip the end of a cig in 25C-nbome solution?

 

[Synaptic Gap]

What i really interested in - smoking is it possible? Dosage?
Can i just dip the end of a cig in 25C-nbome solution?

DONT DO THAT!!! You will have no control over the amount of compound you have on that cig plus you are using an experimental ROA on an experimental super potent hallucinogen. Please be careful!

if you want to try smoking it just put drops on a cig or in a bowl with mj. Give it 10-15 minutes for the alcohol to dry out and then indulge. At least this way you can control how much you are getting.

 

[zn13bt]

Anyway back on topic, does 25C-NBOMe leave a taste-associated bodyload after you've been chewing the tab for a good amount of time? Both times I've taken 25I-NBOMe the aftertaste in my mouth led to a weird bodyload for the first hour or two of the trip, which could only be remedied by food, drink, or other drugs. I've heard 25C is a lot more friendly than 25I and if this is the case I'd expect there to be less of any sort of bodyload too, but as it was mostly taste-associated I'm not sure. Any comments?

I get the nasty taste with both 25I and 25C, seems to be about the same with both. Drinking chocolate milk helps to get rid of it. Also, maybe instead of chewing the blotters (which would spread the taste all over your mouth) you could try just sticking them on your upper gum and leave them there for a half hour or so. As long as there isn't too much saliva in your mouth for the time you have the blotter in there then the bitterness should stay mostly in that spot.

It is pretty gross though, and even after 20+ trips I haven't gotten used to it One of these days I'll finally give up and just stick some NBOMe solution up my butt instead 8(

 

[zaggy]

I do not have confidence in the safety of this compound. I was reckless one night and tried 25C at 1.4mg, and had severe vasoconstriction and uncomfortable stimulation when the peak of the trip started to decline. It was painful and unpleasant to say in the least. I don't particularly enjoy getting to the point where you consider the possibility of seeking medical attention. Thankfully I was able to counteract it using home remedies, meditation, and my damn undying will to live.

The negative effects seem to really vary from person to person.

 

[Dondante]

Based on reports out thus far, the NBOMe series appears to be less safe than many other psychedelic compounds.

There are reports of seizures at 3 and 4.5 mg, with potentially fatal hyperthermia/hypertension/tachycardia at 4.5 mg...I believe both were nasal administration. Also, there is a report of a seizure with 2C-I-NBOMe at 1 mg insufflated. The risk likely varies quite a bit based on an individual's physiology (e.g. seizure threshold), but there's good reason not to push the envelope with this chem.

 

[MDMAPhreak]

I had two friends last night jump to 2.5mg apparently. Let me say this was against my recommendation to them and I'm not sure how they went about it particularly besides the fact they used it intranasally.

All I know is they had a 2mL vial at 2.5mg/mL. They apparently split this last night and when I worked with one of them today he was beginning an 8 hour shift on 5 hours sleep feeling pretty well. This in no way means that this molecule is safe and I don't want anybody believing so just because me and a few others have done so. I also have a friend that doses 1.2mg up the nose all within 15 minutes and loved his night. Just some observations.

 

[zn13bt]

How long did you wait before redosing? If it was more than an hour, then tolerance may have set in already and the second dose wouldn't have had much effect. I'll bet if you do 2mg all in one go it'll be a lot more intense (and probably more vasoconstriction and other bodyload too).

 

[MDMAPhreak]

I haven't felt any vascoconstriction or bodyload from this chemical at all. Would I not feel it even if the psychadelic effects are not felt? I would think if somebody uses 2mg at once and 2mg in 25-40 minutes it would have the same body load either way?

 

[freedstar]

I've tried to understand the safety of these as well.The vasoconstriction and seizures are worrying. Does this happen with LSD at high doses? Say x15 a normal dose or however more potent it is then LSD.

How unreasonable is it for a psychedelic to be unsafe? They may be too potent.

 

[Blake7]

I'll post this here as although it relates to 25I-NBOMe, given the similar dosage requirements between the NBOMe's I feel I'ts relevant to post this here.

Let this be a warning doublr check your maths and then check it again.

http://www.bluelight.ru/vb/threads/...g-Intravenous-first-time-please-don-t-do-this

 

[Redbong]

25c numbs my mouth like coke does, or Novocaine. It definitely has my mouth feeling funny for the first couple hours of the experience.

I was thinking one time, what if early dentists found nbomes before cocaine? That'd make for some pretty crazy tooth extractions. People are already terrified of the dentist. That could've severely traumatized people. Just a thought...

 

[Mortimer McFury]

The more I research and the more times I dose this NBOMe the more confident I become in its safety. I understand that it is an RC and very little to no studies have been done on it as of yet but the science seems pretty sound to me. Create a class of molecules that lowers the potentiated dose of a molecule considerably (thus less of a substance in your body), and have these molecules target a single receptor for agonization instead of multiple receptors for less flooding of neuro active chemicals in the brain thus leading it to be less neurotoxic.

Psychedelics aren't usually neurotoxic, partial agonism is rarely harmful. You're not right about the selectivity making the drugs safer, and actually NBOMe substances are particularly dangerous precisely because of their highly selective action. When you only activate 1 type of stimulatory serotonin receptor like 5-HT2A without the inhibitory receptors also being activated then there's no mediation in effects. I don't think NBOMe drugs are unreasonably dangerous though, they just don't have the ridiculous safety record of LSD where you can take hundreds upon hundreds of doses.

 

[bluedolphin]

I've tried to understand the safety of these as well.The vasoconstriction and seizures are worrying. Does this happen with LSD at high doses? Say x15 a normal dose or however more potent it is then LSD.

How unreasonable is it for a psychedelic to be unsafe? They may be too potent.

Seizures have certainly happened on LSD, as they have on mushrooms, MDMA, and I'm sure just about all psychedelics that have seen widespread use.

However I highly doubt 1500ug of LSD is vastly more likely to cause a seizure than 250ug of LSD. Other typical physical side effects of LSD seem to max out at a reasonable dose, not that there is a correlation to be found in this statement. Then again the most LSD I've taken at once is somewhere between 1mg - 1.4mg so I couldn't tell you what it's like in super-mega-doses.

Seizures with LSD are obviously not very common, but when people are partying on acid and have a seizure (just ask festival med teams if this ever happens) it's obviously because the acid lowered their seizure threshold.

Also, just because a molecule is very selective (nbome's) vs. a wide spectrum of activity (LSD) does not mean it's at all safer. The safest drugs seem to me the ones that act upon the brain with some sort of balance (cannabis being a prime example).