The Big and Dandy NBOMe-2C-C (25C-NBOMe) Thread

[psood0nym]

^That's why I think injection is probably the best for determining the dose with this difficult material. It's the only way to know we're getting specific amounts into the body at titrated doses that become active quickly enough to add more without running up against quickly developing tolerance issues. 50 ug followed by another another IM dose 30 minutes later, whose size will depend on how strong the first 50 ug dose is, will hopefully be fast enough to avoid the development of serious tolerance while still offering some increase in safety through titration. You might be able to do the same thing with multiple pre-measured vaporized doses since they reportedly give results within 5 minutes (it's just that vaporization isn't the most precise dosing method).

 

[any major dude]

took 450µg sublingually friday evening. Doubt all of it was absorbed, definitely +++, but on the low end of that, maybe more like +2.5. I'll probably experiment with some alternate ROAs with this one, the sublingual dosing is just too iffy. That and the relative inability to redose effectively are a good enough reason to try insufflation & possibly vaporization, unless i can find some of those handy glycine tablets erny was talking about a few pages back.

As for the substance itself, really enjoyable. Definitely psychedelic, but in a very talkative sociable way. Duration seemed pretty manageable as well. Dosed about 7, started feeling effects in about half an hour, in full swing around 9, effects starting to fade around midnight-1, came home at two, entirely down by 3, asleep a little later. Could've gone to sleep before i did, just got really interested in an episode of the universe on netflix, so i stayed up & smoked some JWH-200 & 073 while watching that, then went to bed.

 

[happydaze]

It's Nichols NBOMe analogue of 2C-C I believe. Extremely potent, however only if taken intranasally if I remember correctly.

Correct me if i'm wrong, im going solely off of information from lab's who ive talked to regarding the synth of this product as well as chemists and RC enthusiasts.

Id advise checking in ADD as there will definitely be more info on the NBOMe substances, if not this substance itself.

I snorted 20mg of 2c-b once and it was a MAJOR regret lol! If its anything like that I would gladly pass as snorting any 2c compound hurts worst( is it worse or worst?) then being burnt by gonorrhea haha

 

[IGNVS]

hey pseudo, i was logged in as a friend. african dream root tea is easily whipped up into a frothy bubbling mess, and the sapponins are emulsifiers. i just figured it might have similar proporties is all...

 

[psood0nym]

^You may be right, I just didn't find anything in that specific search. Pictures of micelles remind my layman mind of soap, which emulsifies. The fact that just polysorbate 80 and licithin were mentioned makes it seem like you need a specific type of micelle when it comes to 25C-NBOMe, though, and I have no idea what qualifies. I'm not too bothered to find out though, since I'm just gonna do the elegant thing and stab it through the problem with a needle!

 

[any major dude]

do tell how that goes. I'm definitely thinking sublingual isn't the best ROA, even though i have yet to try others. Can't decide whether to vape or do some type of nasal administration next...

 

[skillet]

Rectal works ok, and is probably more consistent than sublingual.

 

[any major dude]

ah, i'd totally forgotten about that hole

And why would injection avoid the redose-tolerance issue? I'd assume that would happen so rapidly as to make ROA inconsequential

 

[psood0nym]

Injection, like vaporization, would theoretically work fast enough to avoid developing substantial tolerance AS the compound absorbs (see post #212). It is the development of tolerance as the compound slowly absorbs that is thought to account for the radical differences in dose response between ROAs (typically vaporization would be about twice as potent as oral, but here it's more like 5Xs as potent, as is rectal adminstration (but ONLY with polysorbate 80 to help it absorb faster). That is, tolerance for this compound is thought to develop much more rapidly than for something like DMT or LSD.

Has anyone used these enough to estimate how long tolerance takes to come down after using an NBOMe? Days? Over a week? I'm just thinking anyone planning a psychedelic weekend might be very disappointed if they started with 25C-NBOMe on day one.

 

[Cface]

If the meph generation gets a hold of them, the results could be disastrous...

Funny you mention that, as it appears to be on-sale right next to 4-mmc on a certain vendors page.

I looked at the chemical, seemed interesting, but as i read more about dosage i decided to stay far far away as i tend to need substances much more dose-forgiving.

 

[MattPsy]

this should get interesting

 

[Solipsis]

A couple weeks back I was worried it was gone and I was left to choose 25D which sounds much less interesting. But its 25C now, the tiniest sample that I will be making liquid of - putting on blotter has been considered but obviously never to be passed off as acid, that would be economically silly anyway if it wasn't something despicable to do. Will probably just keep it as liquid (vodka).
Buccal absorption sounds fine, if it is really concentrated maybe intranasal liquid could have better efficiency but I would worry about seepage a little bit.

 

[atara]

Putting an NBOMe on blotter and passing it off as acid wouldn't work because people would swallow the tabs and there'd be no effect. You'd piss a lot of people off because they didn't know how to properly dose.

I mean, yeah, LSD usually works better sublingual, but there's a good proportion of people who don't realize that.

 

[MagickalKat777]

This sounds like such a tricky class of compounds, the NBOMe's...

 

[any major dude]

Injection, like vaporization, would theoretically work fast enough to avoid developing substantial tolerance AS the compound absorbs (see post #212). It is the development of tolerance as the compound slowly absorbs that is thought to account for the radical differences in dose response between ROAs (typically vaporization would be about twice as potent as oral, but here it's more like 5Xs as potent, as is rectal adminstration (but ONLY with polysorbate 80 to help it absorb faster). That is, tolerance for this compound is thought to develop much more rapidly than for something like DMT or LSD.

Has anyone used these enough to estimate how long tolerance takes to come down after using an NBOMe? Days? Over a week? I'm just thinking anyone planning a psychedelic weekend might be very disappointed if they started with 25C-NBOMe on day one.

thanks for the info, & i was wondering about the longer-term tolerance issues as well. The next time I take some 25C-nBOMe i may dose a 2c or 4-sub trypt a couple or three days later just to see if it has a more substantial long term tolerance than the parent compounds. I kind of doubt it would, but I've got no scientific basis for that, just an assumption.

Putting an NBOMe on blotter and passing it off as acid wouldn't work because people would swallow the tabs and there'd be no effect. You'd piss a lot of people off because they didn't know how to properly dose.

I mean, yeah, LSD usually works better sublingual, but there's a good proportion of people who don't realize that.

I'm kind of glad this is the case. No DOx type disasters with this stuff. Hopefully

 

[atara]

This sounds like such a tricky class of compounds, the NBOMe's...

If one can actually get them into the bloodstream they're a great time, but so far all that's worked for me is insufflating a solution and that is not so pleasant!

 

[skillet]

I really don't see the problem with plugging these, it works fine and you don't have to deal with trying not to swallow a mouth full of saliva for 20 min or snorting nasty tasting liquids or tiny amounts of solids!

 

[atara]

It would require equipment and skills I don't have is the problem. If I'm going to learn a new and complicated ROA it's probably going to be IM or IV.

 

[amanitadine]

? Now wait a minute, I'm almost certain you have a butthole.....and it seems like a purdy simple proposition....

 

[Aleph]

I have not tried the NBOMe, but the trips I read remind me incredibly my experiences with BDFLY.

BDFLY to 240 micrograms lasts me 6 hours. When testing the NBOMe I can compare more accurately, as each person is different.

25C-NBOMe 200mcg tested insuflated. indistinguishable effects BDFLY in the same oral dose.
I hope test higher doses and expect more reports from other people, but I haven’t high hopes for this compound, BDFLY is much easier to take to be active orally.