The Big and Dandy Ketamine Thread (Next iteration)

[silentscience]

stuff's pretty addictive if you got the good shit. I've found lately that it's hard to come by. most stuff I've been getting has been either not preared properly, cut or just doesnt feel like the stuff i used to get. And its not just tolerance either. I think a lot of its being cut down quite a bit these days. it doesnt even taste right!

 

[Jabberwocky]

does anybody notice how if you binge on ketamine the high becomes more and more dirty after a while? It really turns into a shitty shitty high after multiple days in a row. For me at least.

 

[psood0nym]

I remember suggesting earlier in this thread that people try limiting their use to IM over nasal administration. In my experience, IM is a greater mental commitment (even at the same flat-out intensity), less euphoric, and a whole lot more of a pain in the ass to mess with. The ease of nasal coupled with the possibility of using it in small repeated doses socially was its largest draw.

Obviously the switch to IM didn't do the trick for you Gaian Planes--as I remember you shifting to it from nasal a while back; though, you probably never limited yourself to that route exclusively. I know I went through about 700mg of ketamine nasally in about three weeks once, but it's taken me over a year to use the same amount IM. Clearly, I don't feel the compulsion as much as many do. Still, I could see it at least reducing use for some, even if that reduction is no where near ideal.

 

[LordKrishna]

does anybody notice how if you binge on ketamine the high becomes more and more dirty after a while? It really turns into a shitty shitty high after multiple days in a row. For me at least.

thats cause you are snorting it.

 

[swilow]

I find I start feeling a little bit feverish after prolonged use....and I've never really used it that much. K is almost too good to be true. I'm glad (sort of) I can't obtain it regualrly.

 

[(zonk)]

I read that the antihistamine/anticholinergic muscle relaxant orphenadrine inhibits
the CYP2B6 enzyme from metabolizing K. My Q is, how much orphenadrine would be required for signifigant potentiation and to what degree would the K be potentiated(ie:1.5x,2x,4x etc..)???

 

[psood0nym]

Can you link to a source? The idea of increasing its potency is nice from an economical standpoint, though the prospect of getting more time out of a barrel full is what I find really enticing. I'd like it if there was a drug that didn't color the experience too much that brought K up to the endurance of some of the shorter acting tryptamines, especially.

 

[KinkyKetter]

From the feedback of a couple friends CP 55,940 seams to greatly increase Ks duration and numbness but they couldn't comment about whether it affected the mental part of K because they were already tripping to hard on CP 55,940. CP 55,940 also slows time down considerably, mins feeling like hours. I told my friends to keep that in mind when trying to figure out if Ks duration was still increased and they said they watched the clock to be sure

 

[fastandbulbous]

thats cause you are snorting it.

Nope, IM use becomes unrewarding after a few days of repeated use (like several times a day)

I read that the antihistamine/anticholinergic muscle relaxant orphenadrine inhibits the CYP2B6 enzyme from metabolizing K.

Ketamine is mainly metabolized to norketamine by CYP3A4 isoenzyme; CYP2B6 has a low affinity compared with CYP3A4, so inhibiting it isn't going to do much for extending it's activity (a hell of a lot on N-demethylation is seemingly the responsibility of CYP3A4)

 

[*Love*Lite*]

I have this irrational love/ hate relationship with K... I love low doses, the psychedelic effects, the fuzzy mind space, but I HATE the higher doses that I inevitably end up taking by slowly bumping lines through out the night. The high dose that I am speaking of is when you can not move your body, you confuse your body parts, it feels like your drowning etc.

I have never K-holed, but I will try it on day (IM). Im just too scared to do it because I find the higher doses to be so uncomfortable physically. Anyone else get this??

 

[LordKrishna]

I have this irrational love/ hate relationship with K... I love low doses, the psychedelic effects, the fuzzy mind space, but I HATE the higher doses that I inevitably end up taking by slowly bumping lines through out the night. The high dose that I am speaking of is when you can not move your body, you confuse your body parts, it feels like your drowning etc.

I have never K-holed, but I will try it on day (IM). Im just too scared to do it because I find the higher doses to be so uncomfortable physically. Anyone else get this??

No,

you just got ot be able to push through it. sometime I get flash backs to slavia physical sensations when IVing ketamine and it kinda scares me but I just think thats how dissociatives feel when you are completely zonked. Just be glad its not PCP or some longer lasting dissociative, you only hole like that 35min tops.

And I find low doses to produce only physical effects and a sense of well being, psychedelic comes in the doses you dont like much higher.

I dont know what to tell ya besides maybe cut back or maybe get some racemic ketamine if you are using "s+" currently.

 

[Delsyd]

^its racemic

i guess im lucky in that i can hold on to K without binging on it and yet i still love it, ALOT.

i find using around once a week to be fine and i dont crave more of it during the week. well i do sometimes, but i can hold of till the weekend.
Also when i use it i find 2 strong trips in a night to be plenty, i dont want more after that because i feel too worn out from K sometimes.
In fact sometimes 1 strong trip is enough.

And i find wat psoodonym said about snorting vs IM to be true as far as snorting leaving u feeling more cracked out and having a higher tendency for using more because its so easy to blow a bump rather then prep a shot (though preppin shots is fun in its own right)

mmm, all this talk about ketaine has me cravin some. lol

 

[Jabberwocky]

karma, i find this too. I actually dislike the khole trip very much...it doesn't seem very special to me...its just sensory shutdown...I don't get anything much psychedelic from it....its like anti-psychedelic really (mind-unmanifesting). For me at least.

I prefer to keep it to 30mg bumps...and let those wear off...I just like its purely recreational effects. I also like combining it with psilocin or something AGGRESSIVE like that, since it really takes the fear away.

 

[SKL]

anti-psychedelic really (mind-unmanifesting)

This is an interesting description. Taken in it's most literal sense, I'd tend to agree. A lot of the ketamine experience for me is disintegration of consciousness ... is that a sort of manifestation, though?

 

[Delsyd]

its great with LSD.

this past weekend ~80mg IM'd on top of 2 hits of acid was spectacular.
Made he K almost twice as strong aswell as adding some fun psychedelic twists to it.
i still wish i had shot ~200mg instead.

next time.

 

[Jabberwocky]

This is an interesting description. Taken in it's most literal sense, I'd tend to agree. A lot of the ketamine experience for me is disintegration of consciousness ... is that a sort of manifestation, though?

well I've thought about this before...so I'll expand my thoughts on it here...I really have gotten ZERO from ketamine (other than some time spent feeling REALLY good and a slight psychological addiction )...compared to say mushrooms or LSD...I can tell you tangible things that I have learned and discovered about myself and the world...and a profound sense of awe/respect for reality. Ketamine just hasn't delivered...but maybe its just because of my set/setting...but even when I use acid for fun it still sometimes surprises you and gives you incredibly profundity...so I know sometimes the experience is 'out of your hands'.

I find it hard to believe that others get a lot out of it, given that I get so very little (err nothing) out of it....like I almost want to say its a mistake of the community to consider ketamine (and nitrous) to be spiritual/profound chemical. But, I catch myself, and realize that my experience does not exhaust the experiences of others (ie others can have a different relationship to ketamine than I have). So, I just sit by the sideline whenever the profundity of ketamine is discussed...I just think its pure recreation...

(although that said I think it can have a use for catalyzing intense experiences when you're already on a serotonergic psych, ie it disinhibits you and 'releases' your spiritual body with no fear).

 

[psood0nym]

This is an interesting description. Taken in it's most literal sense, I'd tend to agree. A lot of the ketamine experience for me is disintegration of consciousness ... is that a sort of manifestation, though?

I'd say you're right. As the lights dim down certain things we never knew glowed in the dark are revealed.

Do you get anything out of a combination of ketamine and a serotonergic psychedelic Gaian Planes?

 

[Jabberwocky]

do you find you have to be very careful with your dose psood0nym to find this spot? Perhaps I'm just overdosing then is my problem. I dose around 125-150mg (IM or SC) and that seems light for others...but I have a funky mind, so...

 

[Delsyd]

i think you are underdosing if what you are looking for is a ketamine trip with psychedelic and spiritual significance.

Your dose is under what most would consider a k-hole.

if i were you id give it a shot (pun intended) in the 200-250mg range.

just try it once, for me baby

 

[psood0nym]

Yeah, that would be way overshooting for me. I always use 50-55mg (I weigh 170lbs) with a 5-HT psychedelic. I get very little out of ketamine alone (even at 200mg), but at 50mg IM it seems to refocus the fireworks of a serotonergic to isolated little islands of neural populations, which really shifts my perspective around throughout the trip and makes for some really unique experiences.