^^I wouldn't expect too much of an interaction. You might be slightly less sensitive to the substance, but you can titrate up the dose to a comfortable level.
In my book, DPT takes the cake for the most mind-blowing psychedelic ... at higher doses it ceases to be "enjoyable" in the usual sense of the word, but provides possibly the most fascinating state of consciousness I've ever experienced. Start low, and if you are struggling with depression, perhaps you should seriously consider if it is worth putting your mind through such an experience.
I recently tried DPT ... the sheer intensity was overwhelming. The night consisted of 20 mg AMT IM, followed by 40 mg DPT IM @ T+4:00. The first dose of DPT was outstanding and not threatening in any way … I felt the need to dance like never before!

However, less than an hour later I took another 60 mg IM thinking that the first dose may have started to subside ... oh was I wrong!!!
The next two hours are best described as a mind-melting blend of utter beauty and horror. The experience was immensely fascinating, but has left me feeling that I need an extended break from all drugs. I need a few months to really grasp everything that happened that night and try to integrate as much of the experience as possible. I fear that if I ignore and try to forget the experience there will be some psychological repercussions. DPT has humbled me! It truly is a powerful sacrament.