Requests Suggest a research topic

I'd like to see someone develop a 5-HT2a super agonist and see how it effects people, but I dought a study like that will ever happen.
 
MedicinalUser247 said:
I'd like to see someone develop a 5-HT2a super agonist and see how it effects people, but I dought a study like that will ever happen.
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Outside of what is on wikipedia I found this agent:

pubchem.ncbi.nlm.nih.gov

5-HT2A receptor agonist-1

5-HT2A receptor agonist-1 | C15H22ClFN2 | CID 156836299 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
pubchem.ncbi.nlm.nih.gov pubchem.ncbi.nlm.nih.gov
 
i wonder if any of the carbamates are any good, e.g. meprobamate.

i read Mebutamate is stronger than this though.
 
Sr 17018 for opiate detox. Or any other RC that could provide more comfortable detoxes. The traditional treatments available seem overmatched against the new age of super high strength opiate abuse
 
neversickanymore said:
This is a tread where you can suggest and we can discuss research topics with the Drug Studies research community.

What could we all be looking at?
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Litterally? Well, i'm quoting verbose and shall stick to it then!

Long long ago the topic of coughing focussed plenty of attention on temperature and dryness characterising cannabis vapour, which to me resulted in a « Prototyping Platform » where cooling & moisturization could be conveniently combined in a variety of ways:

10-Fog-Bong-Conceptual-Schematic-Formerly-a-Gi-F-Tiny-Pic-6px7r4-2012-Nov-17-270x350.png

Starting from there i knew i wanted water so my next move was to choose an existing product to serve as yet another prototyping platform, which this time required quite many more years to tweak while i was becoming aware of "packetization" under the form of this law applying to elementary thermodynamics:

Specific_Heat_formula_300x200.png

Which once applied to my selected tool resulted in a 2-phase scenario:

David-vs-Goliath-Burst-mode-Sling-Analogy-480x230.png

First a fixed amount of energy matching its associated workload was accumulated temporarily, next it got briefly released into a Bi-Energy compatible bowl eventually inviting Induction Heating, so to better apply Pulse Heating which promotes aroma/taste appreciation, basically by avoiding combustion by virtue of the Curie effect and much more as a bonus.

Initially my Hybrid Core would be structured following one of 2 possible topologies:

Egzoset-s-LAVA-Bi-Energy-Capsule-2017-May-26-400x400.png

Egzoset-s-Lava-Bi-Energy-Capsule-Sliding-Control-see-Cust-VG.gif

OR
​
Egzoset-s-idea-of-some-IH-Driven-Heat-Convertor-2019-Mar-28-7.png

Si-C-Puck-wrapped-by-Susceptor-with-2-5-mm-Beads-layer-plus-2-mm-wall-2024-Aug-31-340x360.png

My LAVACapsule model was made of two customized VG "tops" where half of it sufficed to complete a pipe, that later alternative being a proven "Plan-B" (butane-based) option. The co-axial heat convertor concept didn't get this advanced in terms of factual experimentation but it still should fit nicely inside a modified retro-compatible full-metal top/sphere, shown below:
​
Egzoset-s-Cust-VG-Classic-alu-Routine-Tool-23-10-Years-850x290.png

What's unique about it resides in support of real-time "scanning" of the vapour combined to cotton sampling allowing collection of data where opacity, pressure and speed can be paired with a physical sample of what was actually inhaled.

Ultimately i would like to see the results analyzed through these 4 "reality-filters" of mine:

#1) Neuro-plasticity; ​
#2) Contaminants; ​
#3) Consumption Method & Ritual; ​
#4) Socio-toxic 3rd-party interference​

P1, P2 and P3 are fresh-air « PinHole » inlets, with a manual option at P2 so to enhance the consumption method & ritual (item #3). Contaminants (#2) would be monitored via the cotton sampling, packetization of the stored energy as a function of bowl weight/size (#4) would eventually affect a previously acquired habit (e.g. practically imposed by an environment shaped by society) and even allow to unlearn it (#1) as i've myself verified personally, even late into the 3rd age.

The « FlexValve » is a final refinement trying to manage more suitably with clean-burning butane that remains contaminated with "traces" from the torch-lighter and its butane can: its pinching reduces intake during a pre-heat phase almost without giving it any voluntary thought. The set of « Bio-Feedback » ports is where optical fibers will insert, 2 for the illumination, 2 more for sensing; having a pair of them is how i figured pressure and airflow speed could be extrapolated while a single one can only measure opacity.

In conclusion i can see two main purposes for such device configurations: one for objective investigation, the other for socialization under the form of a karaoke game where sessions are displayed in real time for all to compare with health-wise « HR » signatures reflecting conclusions of the previously built database...

Good day, have fun!! ☮️
 
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Something I was interested to see in research would be the effectiveness of a melatonin antagonist for the treatment of excess daytime sleepiness or shift work disorder. From what I looked up, I saw a drug called 'Luzindole'. Are there any published studies that meet this criterion? If not, it could be interesting for research.
 
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