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OD Moderators: Keif’ Richards | negrogesic
Bupe Suboxone questions
- Thread starter dkst13
- Start date
spork
Bluelight Crew
Welcome to Bluelight. 
I'm going to move this over to Other Drugs since New Member Introductions is a thread to make an introduction to Bluelight rather than ask specific drug questions such as this. You should get more views and responses in OD as well. Feel free to come back to NMI to post an intro thread!
I'm going to move this over to Other Drugs since New Member Introductions is a thread to make an introduction to Bluelight rather than ask specific drug questions such as this. You should get more views and responses in OD as well. Feel free to come back to NMI to post an intro thread!
SkagKush
Bluelighter
- Joined
- Sep 3, 2010
- Messages
- 2,532
You can drop down as quickly as you want, as long as you keep it pain free. However, I'd suggest letting you blood levels level out for two weeks before dropping doses again.
Out of curiosity, what is your intention with lowering your dose? ( Dont get me wrong Im all for maintenance on low doses, but for some people a slightly higher dose can be beneficial until they are more stable )
Out of curiosity, what is your intention with lowering your dose? ( Dont get me wrong Im all for maintenance on low doses, but for some people a slightly higher dose can be beneficial until they are more stable )
Go as fast as you can stand man, usually jumping down from 16 to 8 is fairly easy, but once you get below 6mg it starts to get uncomfortable .
Becyase if the extremely long half life of bupre, the bup builds up in your system and you won't notice a drop until a week after you drop down.
I went from 16mg a day to 1mg a day in a month, and I feel soooooo much better on 1mg a day. Sometimes ill te 2 or 3ngs a day, but I never go over 4mg becyase supposedly is the cut off for more agonism than antagonism.
Bupres main metabolite is norbup which is a full agonist. When you take doses below 4mg, you leave space for norbup to bind. Say you have 10 opiate receptors (hypothetically). At levels of 4mg an below, bup will only fill up and bind to say 4 or 5 receptors leaving the other 4 or 5 receptors empty giving a chance for norbup to bind to receptors . Essentially at low doses, you get more of a full opiate feel and bupre acts as a prodrug meaning its metabolites is what gives the bupre its opiate feel. It's not a true pro drug because bup definitely bind to receptors, but still.
Good luck man, low dose bupre is really the way to go. I've been at 2mgs and below for over 6months now and I am able to function, and live seemingly normal life. Idk how to describe it, low doses just feel more natural and less antagonistic which tuends to make me really nauseous and gives me headaches, and you are putting more naloxone in your system which really fucks with me sometimes and gives me random nausea spells and headaches. The nausea is debilitating too like ill just throw up and lay on the couch, it sucks
I ended up switching to subutex, well like subutex in that its pure bupren. I am prescribed generic buprenorphine tablets withouth nalxone, I feel they really make a difference without shitty nalxone which basically does nothing but give you side effects like nausea and shit. I'm glad I'm on pure bupre because I don't get nauseous anymore and it is literally half the price of suboxone. Also I snort my sub and sub pills are being discontinued so bupre tablets are thr way to go IMO
Becyase if the extremely long half life of bupre, the bup builds up in your system and you won't notice a drop until a week after you drop down.
I went from 16mg a day to 1mg a day in a month, and I feel soooooo much better on 1mg a day. Sometimes ill te 2 or 3ngs a day, but I never go over 4mg becyase supposedly is the cut off for more agonism than antagonism.
Bupres main metabolite is norbup which is a full agonist. When you take doses below 4mg, you leave space for norbup to bind. Say you have 10 opiate receptors (hypothetically). At levels of 4mg an below, bup will only fill up and bind to say 4 or 5 receptors leaving the other 4 or 5 receptors empty giving a chance for norbup to bind to receptors . Essentially at low doses, you get more of a full opiate feel and bupre acts as a prodrug meaning its metabolites is what gives the bupre its opiate feel. It's not a true pro drug because bup definitely bind to receptors, but still.
Good luck man, low dose bupre is really the way to go. I've been at 2mgs and below for over 6months now and I am able to function, and live seemingly normal life. Idk how to describe it, low doses just feel more natural and less antagonistic which tuends to make me really nauseous and gives me headaches, and you are putting more naloxone in your system which really fucks with me sometimes and gives me random nausea spells and headaches. The nausea is debilitating too like ill just throw up and lay on the couch, it sucks
I ended up switching to subutex, well like subutex in that its pure bupren. I am prescribed generic buprenorphine tablets withouth nalxone, I feel they really make a difference without shitty nalxone which basically does nothing but give you side effects like nausea and shit. I'm glad I'm on pure bupre because I don't get nauseous anymore and it is literally half the price of suboxone. Also I snort my sub and sub pills are being discontinued so bupre tablets are thr way to go IMO
The amount your willing to drop can only be determined by you and how much discomfort your willing to feel.
Ask yourself if you would rather feel mild-moderate withdrawal with a slow taper meaning a longer period of withdrawals, or would you rather feel moderate-severe withdrawals with a fast taper on a shorter period of withdrawals.
Ask yourself if you would rather feel mild-moderate withdrawal with a slow taper meaning a longer period of withdrawals, or would you rather feel moderate-severe withdrawals with a fast taper on a shorter period of withdrawals.
i are spectre
Bluelighter
man youve been on 23 days and thats it; jump off ASAP if you know whats good for you.
Mr.Scagnattie
Bluelighter
Yes, the fact that you haven't been on it for a long time will help big time... it'll make it much less painful when you do decide to hop off, at whatever dose. Of course, to make it even more bearable, get down to as low of a dose as you can.. Getting below 4mg's and then 2mg's is tough for a lot of people.. the toughest part of tapering bupe. I'm a big proponent of the 1 month suboxone taper.. I've seen it work really well. But, if your not ready to get off you're not ready.. another few weeks won't kill you if you are in fact having trouble getting your dose down, but if you aren't... than by all means, hop off. Start decreasing your dose a little each day and see how you feel. When you get to .50mg's, try and not take it the next day and see what's what.
mardoux
Greenlighter
seriously! i've been on it for five years and its a huge evil monkey on my back. i quit herion cuz i never wanted to get sick again and now here i am, occasionally running low and it's the same effin thing! stop while you can like i are spectre says!