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OD Moderators: Keif’ Richards | negrogesic
Bupe Suboxone/Buprenorphine FAQ & Megathread v3; 2010 - 2022
- Thread starter Thekid331
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HdoubleODeezy
Bluelighter
oops my bad then.. sorry.
kitschstitch
Greenlighter
advice needed on liquid buprenorphine...
so, i need to detox from a pretty heavy daily habit and i have some liquid buprenorphine (it was actually prescribed to my cat for pain, but she doesn't need it anymore), but i looked everywhere and i can't find any information on bup in the liquid form (for humans anyway)... does anyone know dosing information or what the best/most effective route of administration would be?
any information would be helpful, and i would really appreciate it! i can't live like this anymore and i have been on the waiting list for a detox program for months and i am still not supposed to get in to it until march... so this is pretty much my only option at this point cause i cant afford to go to a real doctor.
thanks again in advance!
so, i need to detox from a pretty heavy daily habit and i have some liquid buprenorphine (it was actually prescribed to my cat for pain, but she doesn't need it anymore), but i looked everywhere and i can't find any information on bup in the liquid form (for humans anyway)... does anyone know dosing information or what the best/most effective route of administration would be?
any information would be helpful, and i would really appreciate it! i can't live like this anymore and i have been on the waiting list for a detox program for months and i am still not supposed to get in to it until march... so this is pretty much my only option at this point cause i cant afford to go to a real doctor.
thanks again in advance!
yo0123yo
Bluelighter
i have only tried suboxone twice in my life..one year ago and 48 hours ago...48 hours ago i took 2mg sublngually and yesterday i took one 30mg roxi which i didnt FULLY feel but i felt maybe about 60% of the effects...my question is did i not feel it as much because my opiate tolerance was raised by the suboxone or should i be ok to take the oxy now 48 hours after the only dose of 2mg sub? and another question is have is does suboxone raise your opiate tolerance at all?
OlCapone
Greenlighter
So what do people think of the alcohol thread can't find the merge..but anyways who here has done a strip with a ml to 2ml of alcohol with their bupe and was it the strips? Please tell experience, and tolerance story kinda what kind of user were or are you, on bupe. I think the alcohol thing, and cimitidine help it just may not be much..Really there is no high so to speak with bupe, but I'll tell you it'll make you run to the shitter. So yes it does hurt. Long time no talk, I brought this up somewhere yesterday, but have not seen any responeses..HAVE FUN BE SAFE TAKE CARE. Peace and Love!
The best way to take it for your purposes is through an I.M. injection. As for dosing, I would start with .3 mg and then move up from there based on how you feel. Beware that in my experience it can take up to an hour and a half to reach peak effects, so don't go crazy redosing just because you don't feel much within 10 minutes.
Sorry if i am putting this in the wrong section but i am very new at using this website. So I have been taking Suboxone for over 3 years. A friend and I had gotten into opiates pretty bad. She was shooting Oxys and Heroin eventually, and I was snorting it. We did this together for a few years. Long story short- she ended up getting inpatient treatment and I did not. When she got back from treatment she was on Suboxone. She started to sell it to me and this has been the story now for a little over 3 years. I probably average one 8 mg tab a day if not more (honestly a lot of times it is more). the thing is that i am tired of buying them from her. It's getting expensive, i have to sneak around to do it and it just really needs to end. It goes without saying that i am pretty worried about the withdrawal and i feel i have more of an addiction issue now than when we were doing the Heroin. I was thinking about seeing an addition specialist and am wondering if i could get prescribed what I have been taking for all of these years. What do doctors do when you are addicted to the stuff they give people to help with their addiction? Does anybody have any insight? Oh yes and btw- I have a long history of poly substance abuse with my Drug of choice always being opiates. I was in treatment about 6 years ago for opiate addiction.
cj
Bluelight Crew
Your story is not uncommon at all I have met a few people with similar storys at my sub doctor. you shouldnt have any problems getting it prescribed just tell them what you told us and you will be good.
Carl Landrover
Bluelighter
Don't know if you're still looking for an answer, but I'd say you most likely wouldn't feel any of it.
You've been taking sub daily for a while? It's built up in your system and would take longer than 24 hours to feel a dose as low 30mg of oxy. Taking 4mg of sub is much, much more powerful than 30mg of oxy.
SubDude
Bluelighter
I'm sure there are a lot of addict cat lovers who would like to meet that vet. Seriously, liquid bupe for pain in us humans normally come in .2mg vials. So I can't imagine you having very much and your question needs more specifics to be properly addressed.
skittlez_29
Greenlighter
- Joined
- Sep 29, 2011
- Messages
- 9
I have been on the film for about a month and a half. I can recall getting high off the tablets years ago and feel literally nothing from the film. I wonder if its cuz my tolerance to H went up dramatically prior to getting on the film or what. As for the taste, it still tastes like shit. My prescription is for (3) 8mg 3 times a day. I have only been taking 1-2 8mg strips a day tho. Seems to work fine. NOW, I do not care for ppls opinions on what I am about to do. ONLY from personal experience with it PLEASE. I just purchased some H and I am going to do it. The last time I took a sub film was around 4pm. I also took one around 10am. So today I had 2 films total. How long should I wait until I shoot my H so I can feel high?
Your not getting high because the 4-8mg dose that is being absorbed is simply too much. But if your taking it everyday, you honestly need to wait until tommorow to do the H, as bupe has a very, very long half life, especially when taken sublingual, and 2 strips a day is a HUGE dose, relatively speaking, and more than you need honestly, but since you are taking that much everyday, you need AT LEAST 24 hours before doing a full-agonist, preferably 36, otherwise you are wasting good dope!
But do whatever pleases you..
But do whatever pleases you..
SubDude
Bluelighter
I personally wouldn't use another opiate from bupe maintenance until you are starting to feel like you need to dose... which for most is 24-36 [as lorene says] depending on dosage, metabolism... etc. I've been on ORT for 30+ yrs and after switching from MMT to BMT I dropped down to 1 mg. So I can use oxy, heroin or any opiate and get most all of the full effects at 24 hrs.
cire113
Bluelighter
honestly man im done taking oxy or h and stopping my sub... yeah you get high but after that you just gotta use to feel normal.. not even high anymore;
i'd rather just take my bupe everyday and forget about it; Plus it become the same as bupe..
take it or be sick
i'd rather just take my bupe everyday and forget about it; Plus it become the same as bupe..
take it or be sick
SubDude
Bluelighter
^ thats the only reason I take 1 mg and if it didn't come free, don't know if I could justify it??
MikeySpikes
Greenlighter
- Joined
- Aug 27, 2011
- Messages
- 43
I took a sub, 12 hours later shot dope. Can I take another sub?
Or will I get pwd
I shot up around 8 30 it is almost 11 30. I didn't really feel the dope, it was a combo of very shitty dope and re SUBs. Can I redoes
Or will I get pwd
I shot up around 8 30 it is almost 11 30. I didn't really feel the dope, it was a combo of very shitty dope and re SUBs. Can I redoes
Captain.Heroin
Bluelight Crew
Do you feel withdrawal yet? If not, I wouldn't take it to be on the safe side.
I don't think you'll die from taking any amount of Suboxone, unless you're already on a lot of other CNS depressants.
I don't think you'll die from taking any amount of Suboxone, unless you're already on a lot of other CNS depressants.
Pegasus
Ex-Bluelighter
- Joined
- Aug 15, 2006
- Messages
- 8,073
Here's a study on Suboxone/ Subutex overdoses in children:
So they are saying 4mg orally in kids is pretty much always benign, and up to 8mg could be treated with home care. Oral administration is of course about half as potent as sublingual, but I imagine these kids chewed the pills instead of swallowing whole, which surely delivered a decent amount of the drug through the mouth.
Toxicity of Buprenorphine Overdose in ChildrenHayes BD, et al
Pediatrics2008;121(4):e782
This is one of the few reports of consequential overdose of buprenorphine in children. The retrospective review covers three years of data collected from poison centers for children under 6 with a history of BPN ingestion. There were 86 children who met the criteria, with a mean age of 2. The vast majority of ingestions occurred at the child's home, and all ingestions were considered unintentional and acute. The most commonly ingested was sublingual Suboxone, (BPN:naloxone in 4:1 ratio), either 2 mg or 8 mg, with a small number of Subutex (BPN only, no naloxone) tablets.
Interestingly, 26 percent of the patients were managed at home by the poison center without complications. More than a third of the patients remained asymptomatic, 50 percent had minor effects, and seven percent (six) patients had severe effects. Only those with follow-up were included in the analysis. There were no fatalities.
The most common clinical effects were those suspected from an opioid: drowsiness, lethargy, vomiting, and miosis. Respiratory depression was seen in six children, and coma occurred in two. It required about an hour for symptoms to become obvious in those who developed them, but symptoms were delayed up to three hours in a few cases. Although the study suffers from reporting bias, relied on historical recall, and lacked laboratory confirmation, the mean dose of BPN ingested was reported as 3 mg. Tablets are available in 2 mg and 8 mg strength. Sublingual Subutex is a white tablet; Suboxone is an orange tablet. One child was reported to have ingested 24 mg, and those ingesting the higher doses tended to have more significant symptoms. A 4 mg dose was apparently benign in all cases. In this retrospective analysis, a 4 mg ingestion appeared to be the cutoff for concern or need for a mandatory EP evaluation (gutsy move, if you ask me).
Minimal gastric decontamination was initiated. One patient did require intubation and mechanical ventilation. About one-quarter of the patients received naloxone, and the vast majority had some response. Dosing parameters were vague because the dose or indication for naloxone was not recorded in all cases. It has been reported that large doses of naloxone, sometimes 10 times the standard dose, is required to reverse BPN respiratory depression.
The authors note that BPN overdose is essentially an opioid overdose, and it produces CNS and respiratory depression, miosis, and occasional vomiting. Prior reports have demonstrated that accidental oral BPN overdose, even in children, is usually quite benign. Serious toxicity is not to be expected, and was not seen if less than 4 mg were ingested. Because the drug can be dispensed in an 8 mg tablet, the potential for toxicity in a small child is obvious. Although the most common product ingested was the buprenorphine-naloxone combination, the naloxone has no protective anti-opioid effect when taken orally. Only one child required mechanical ventilation, and two were treated with naloxone infusions; the exact reasons for these interventions were unclear.
These authors highlight the usual benign course of an accidental pediatric BPN ingestion, and believe that those merely exposed to a taste of the tablet, even the 8 mg dose, can be safely observed at home. This assumes, of course, reliable parents and a perfect history. Because BPN is usually administered sublingually, swallowing the pill is expected to decrease bioavailability.The duration of clinical effects was between two and eight hours in most patients. The drug does have a long serum half-life, so prolonged observation may be required if significant symptoms are present within the first few hours or if they persist. The potential for delayed onset of CNS and respiratory depression is highlighted, although symptoms will likely develop within two to three hours postingestion if a significant exposure has occurred. The authors suggest a minimum of six hours observation for children exposed to BPN orally, with discharge from the hospital being appropriate if there are no clinical concerns at the six-hour mark.It was the authors' experience that naloxone successfully reversed BPN. It has been stated that exceptionally large doses are required, but that was not confirmed in this study. Due to a paucity of reporting data, accurate naloxone dosing regimens cannot be forthcoming. It was emphasized, however, that the duration of action of naloxone is significantly less than that of BPN. If naloxone is used as a reversal agent, the authors suggest continued observation (not quantified) and perhaps even a continual IV infusion.
Given the increased use of BPN for opioid addiction, the potential for accidental childhood exposure will likely increase. Parents take this drug home, and the orange pill is inviting to a toddler. Interestingly, a veterinary product in an injectable form is available for pain relief in pets, and was involved in some of the exposures in this report. Although limited by retrospective data, the authors conclude that unintentional BPN ingestion is generally well tolerated in children, with respiratory depression being unusual. They suggest that an exposure documented to be greater than 2 mg in a child under 2 should be referred to the ED for evaluation. Others can be observed at home with a reliable (I say, pristine) support system, including reliable parents, transportation, and ability to closely observe. Those suspected of significant BPN exposure should be monitored in the ED for six hours, at which time asymptomatic patients can be safely discharged.
Comment: This article confirms prior reports that accidental oral BPN exposure is relatively safe when compared with the serious consequences of morphine or methadone ingestion in children. While BPN has narcotic effects, this drug only partially stimulates the mu receptors, resulting in clinical effects similar but significantly less than morphine or methadone. One would expect the child or adult overdosing on this product to have a classic narcotic toxidrome (miosis, sedation, respiratory depression, decreased bowel sounds, urinary retention, and perhaps bradycardia and hypotension). The delayed onset of BPN clinical activity is highlighted, but the overall safety of the standard 2 mg tablet, even in a small child, is reinforced.
Pediatrics2008;121(4):e782
This is one of the few reports of consequential overdose of buprenorphine in children. The retrospective review covers three years of data collected from poison centers for children under 6 with a history of BPN ingestion. There were 86 children who met the criteria, with a mean age of 2. The vast majority of ingestions occurred at the child's home, and all ingestions were considered unintentional and acute. The most commonly ingested was sublingual Suboxone, (BPN:naloxone in 4:1 ratio), either 2 mg or 8 mg, with a small number of Subutex (BPN only, no naloxone) tablets.
Interestingly, 26 percent of the patients were managed at home by the poison center without complications. More than a third of the patients remained asymptomatic, 50 percent had minor effects, and seven percent (six) patients had severe effects. Only those with follow-up were included in the analysis. There were no fatalities.
The most common clinical effects were those suspected from an opioid: drowsiness, lethargy, vomiting, and miosis. Respiratory depression was seen in six children, and coma occurred in two. It required about an hour for symptoms to become obvious in those who developed them, but symptoms were delayed up to three hours in a few cases. Although the study suffers from reporting bias, relied on historical recall, and lacked laboratory confirmation, the mean dose of BPN ingested was reported as 3 mg. Tablets are available in 2 mg and 8 mg strength. Sublingual Subutex is a white tablet; Suboxone is an orange tablet. One child was reported to have ingested 24 mg, and those ingesting the higher doses tended to have more significant symptoms. A 4 mg dose was apparently benign in all cases. In this retrospective analysis, a 4 mg ingestion appeared to be the cutoff for concern or need for a mandatory EP evaluation (gutsy move, if you ask me).
Minimal gastric decontamination was initiated. One patient did require intubation and mechanical ventilation. About one-quarter of the patients received naloxone, and the vast majority had some response. Dosing parameters were vague because the dose or indication for naloxone was not recorded in all cases. It has been reported that large doses of naloxone, sometimes 10 times the standard dose, is required to reverse BPN respiratory depression.
The authors note that BPN overdose is essentially an opioid overdose, and it produces CNS and respiratory depression, miosis, and occasional vomiting. Prior reports have demonstrated that accidental oral BPN overdose, even in children, is usually quite benign. Serious toxicity is not to be expected, and was not seen if less than 4 mg were ingested. Because the drug can be dispensed in an 8 mg tablet, the potential for toxicity in a small child is obvious. Although the most common product ingested was the buprenorphine-naloxone combination, the naloxone has no protective anti-opioid effect when taken orally. Only one child required mechanical ventilation, and two were treated with naloxone infusions; the exact reasons for these interventions were unclear.
These authors highlight the usual benign course of an accidental pediatric BPN ingestion, and believe that those merely exposed to a taste of the tablet, even the 8 mg dose, can be safely observed at home. This assumes, of course, reliable parents and a perfect history. Because BPN is usually administered sublingually, swallowing the pill is expected to decrease bioavailability.The duration of clinical effects was between two and eight hours in most patients. The drug does have a long serum half-life, so prolonged observation may be required if significant symptoms are present within the first few hours or if they persist. The potential for delayed onset of CNS and respiratory depression is highlighted, although symptoms will likely develop within two to three hours postingestion if a significant exposure has occurred. The authors suggest a minimum of six hours observation for children exposed to BPN orally, with discharge from the hospital being appropriate if there are no clinical concerns at the six-hour mark.It was the authors' experience that naloxone successfully reversed BPN. It has been stated that exceptionally large doses are required, but that was not confirmed in this study. Due to a paucity of reporting data, accurate naloxone dosing regimens cannot be forthcoming. It was emphasized, however, that the duration of action of naloxone is significantly less than that of BPN. If naloxone is used as a reversal agent, the authors suggest continued observation (not quantified) and perhaps even a continual IV infusion.
Given the increased use of BPN for opioid addiction, the potential for accidental childhood exposure will likely increase. Parents take this drug home, and the orange pill is inviting to a toddler. Interestingly, a veterinary product in an injectable form is available for pain relief in pets, and was involved in some of the exposures in this report. Although limited by retrospective data, the authors conclude that unintentional BPN ingestion is generally well tolerated in children, with respiratory depression being unusual. They suggest that an exposure documented to be greater than 2 mg in a child under 2 should be referred to the ED for evaluation. Others can be observed at home with a reliable (I say, pristine) support system, including reliable parents, transportation, and ability to closely observe. Those suspected of significant BPN exposure should be monitored in the ED for six hours, at which time asymptomatic patients can be safely discharged.
Comment: This article confirms prior reports that accidental oral BPN exposure is relatively safe when compared with the serious consequences of morphine or methadone ingestion in children. While BPN has narcotic effects, this drug only partially stimulates the mu receptors, resulting in clinical effects similar but significantly less than morphine or methadone. One would expect the child or adult overdosing on this product to have a classic narcotic toxidrome (miosis, sedation, respiratory depression, decreased bowel sounds, urinary retention, and perhaps bradycardia and hypotension). The delayed onset of BPN clinical activity is highlighted, but the overall safety of the standard 2 mg tablet, even in a small child, is reinforced.
So they are saying 4mg orally in kids is pretty much always benign, and up to 8mg could be treated with home care. Oral administration is of course about half as potent as sublingual, but I imagine these kids chewed the pills instead of swallowing whole, which surely delivered a decent amount of the drug through the mouth.
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cire113
Bluelighter
Bupe is some POTENT as shit... I mean for pain the formulations are as low as .2 per dosage..
The ceiling on resp depression prob contributes to the low od by bupe alone;; but for some reason mixing BUPE with benzos seems even more danergous then full agonists with benzos...
I guarantee you if Bupe was the only opoid around peopld would be going crazy for that shit...
I have a new theory on bupe... People on maintenance dont feel a high anymore because you basically forget your high all the time; lol...anyone who discredits this and is on Maint.. stop your bupe for 3 days.. then take 2mgs let me know how you feel when you take that 2mgs... Your honor i rest my case..
The ceiling on resp depression prob contributes to the low od by bupe alone;; but for some reason mixing BUPE with benzos seems even more danergous then full agonists with benzos...
I guarantee you if Bupe was the only opoid around peopld would be going crazy for that shit...
I have a new theory on bupe... People on maintenance dont feel a high anymore because you basically forget your high all the time; lol...anyone who discredits this and is on Maint.. stop your bupe for 3 days.. then take 2mgs let me know how you feel when you take that 2mgs... Your honor i rest my case..
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