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Bupe Suboxone/Buprenorphine FAQ & Megathread v3; 2010 - 2022

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Hey!
So I managed to make it to the sub-doc this morning, and get my first subs after quitting heroin yesterday.

I have already dosed 10mg, and still feel like utter shit. I do feel effects of the brurenorphine, but it seems like heroin wd's still come through, making me think that I might as well go cold turkey instead...

I also have a problem with the dissolution of the tabets. When I place one under my tongue, my mouth waters up completely, and it's hard to keep from swallowing. Anyone have any advice on administration? I got so frustrated after the first 6mg that I tried snorting half a 2 mg tablet, resulting in projectile puking all over the bathroom(fun to clean up while in wd's). And I had just managed to eat a banana with yoghurt before that, so now I have a nasty taste of combined subutex, banana and yoghurt in my mouth. Yuurrghhh...

Anyways, I hope that the shitty feeling is just in the startup phase of the substitution therapy - I'm sure it will get better with time. But damn I feel like crap and RLS is still there like mad!

Hope everyone else in the same boat is holding strong!
 
woke up today.. day 12.

felt sort of crappy but not too bad, maybe this is just what it is like to be a normal human again.. I took about 1MG yesterday, with like a .5 MG piece at about 8. It's been like 20 hours and I still feel alright.

I think I may be done! I conquered !
 
dpc1192 said:
woke up today.. day 12.

felt sort of crappy but not too bad, maybe this is just what it is like to be a normal human again.. I took about 1MG yesterday, with like a .5 MG piece at about 8. It's been like 20 hours and I still feel alright.

I think I may be done! I conquered !
Click to expand...

You do know that 1.5mg is a pretty high dose and will stay in your system for a long time? You are just beginning my friend. Good luck!
 
etard7007 said:
alright so ive been in bad opiate withdrawal for 3 days or so... i dont see my pain doctor until new years eve... the pain + the withdrawal has taken a lot out of me... ive been taking tramadol for the past 3 days seeing as i dont have any opiate connects anymore... its helped in that im not having most of the major symptoms like cold sweats, rls, etc... mostly just runny nose, anxiety/insomnia, and about to shit myself every other minute...

anyway i randomly came across an 8mg suboxone... i researched and found that the tramadol i took a few hours ago would not throw me into precipitated withdrawal along with the bupe... so i went ahead and took 2mg of the bupe.

its been 30 mins and im confused... i dont feel better at all im still ab to shit myself... ive never actually taken bupe and from what ive read 2mg should be enough.

any info would help thanks... btw im coming off of ab ~80mg/day oxymorphone IV habit or about 150mg/day insufflated oxymorphone... i never IV and snort on the same day i do either i feel like.
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That is a HUGE habit man (no judgment passed at all) so you may need a full 8 or even 16mg's of bupe. basically, if you were IV'ing 80mg of Oxymorphone, thats equivalent to 800mg of morphine, and bupe is about 50x stronger binding affinity than morphine, so you should have to get 16mg of bupe into your system @ ~35% sublingual, that's surpassing the 32mg max dose. (the math works out to 48mg for replacement) You should go to a sub doctor or talk to your PM doctor about how to manage your pain and dependence.
 
catcalls said:
Sure is a lot. Good luck with that!
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you seem to have an attitude, man.

the dude is happy to be down to that low of a dose, and he is only .5mg from being able to jump off without significant w/d symptoms as .5 is pretty easy to stop as you just take it less frequently until you don't need it.

I'm happy for you dude, just keep going.
 
The past three days have been bliss for me. The holidays were great. Had a delish Xmas meal that I cooked for the family!

And, the best part? Not having to go out to the pharmacy every day!

Yes, I'm on daily supervised Subutex. But, I got a four day supply on Friday. Start daily visits to the pharm on Wednesday.

But, this experience made me feel 'normal' again. And I want to quit Subutex so bad. But, I need pain relief for my gut. The doctors do not know what is wrong with my stomach. For a while, they thought it was psychosomatic. But, after seeing a psychiatrist diagnose me, he stated because I get relief from the Subutex ~ I must be in pain.

So, I really cannot put up with daily collections anymore. I'm seeing my Drug Worker in the New Year and I want to arrange something with either my GP or some PM Doctor to get a larger supply of Subutex, or any pain killer, and not have to go out every day to the pharmacy.

That would be sweet, no?
 
muvolution said:
you seem to have an attitude, man.

the dude is happy to be down to that low of a dose, and he is only .5mg from being able to jump off without significant w/d symptoms as .5 is pretty easy to stop as you just take it less frequently until you don't need it.

I'm happy for you dude, just keep going.
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I'm not the one with the attitude. I was being realistic, and supportive. You on the other hand, seem to be baiting me into a fight.
 
I just wanted to mention that catcalls is actually being realistic.
I was going to post myself but I didn't want to make dpc feel bad.
But seeing as someone else pointed it out I figure I might as well toss my experiences in as well
I've been doing .5mg to 1mg a day & still get significant w/d's if I try to come off it.
I just didn't want to ruin dpc's happy thoughts.

Though if dpc is one of the lucky one's he might be able to jump off pretty easily as I've seen some people do so.
I sadly enough am not one of those people as jumping off even at .5mg is very unpleasant for me.

Regardless please don't draw me into any in-fighting or bickering. :)
I'm just posting to add my 2 cents that not everyone can jump off at that dose & get away easily.
Some of us need to go even lower.
Hell I jumped once at .25mg a day & still had mild to moderate w/d's.

Either way best of luck to you dpc!
Also congratulations on doing well on your taper.
 
muvolution said:
you seem to have an attitude, man.

the dude is happy to be down to that low of a dose, and he is only .5mg from being able to jump off without significant w/d symptoms as .5 is pretty easy to stop as you just take it less frequently until you don't need it.

I'm happy for you dude, just keep going.
Click to expand...

I understand what your saying about there might have been some attitude there(or not, who knows) but I think catcalls was just trying to make a very good point that might help dpc1192. Because he seemed to think that taking 2 0.5mg doses a day was pretty much "conquering" his sub dependency.....when the truth is, a 1 mg dose is not about to let you quit without really bad WD's that last a long time....you need to be down to atleast half that, probably less....and stay there for a while before you can consider yourself a "conquerer".
I understand catcalls possibly could have been more "polite" maybe, but there was a very good point to be heard and I hope the lack of respect given doesnt blind your eyes to whats the true reality here(whats goin on with the sub dependency).
Good Luck
 
muvolution said:
you seem to have an attitude, man.

the dude is happy to be down to that low of a dose, and he is only .5mg from being able to jump off without significant w/d symptoms as .5 is pretty easy to stop as you just take it less frequently until you don't need it.

I'm happy for you dude, just keep going.
Click to expand...

catcalls said:
I'm not the one with the attitude. I was being realistic, and supportive. You on the other hand, seem to be baiting me into a fight.
Click to expand...

Ladies, Ladies - you're both pretty. If you want to offer advice, support, insight or information then feel free but if you want to make this shit personal, take it to PM's; it has no place on the forum.



________________________

muvolution said:
That is a HUGE habit man (no judgment passed at all) so you may need a full 8 or even 16mg's of bupe. basically, if you were IV'ing 80mg of Oxymorphone, thats equivalent to 800mg of morphine, and bupe is about 50x stronger binding affinity than morphine, so you should have to get 16mg of bupe into your system @ ~35% sublingual, that's surpassing the 32mg max dose. (the math works out to 48mg for replacement) You should go to a sub doctor or talk to your PM doctor about how to manage your pain and dependence.
Click to expand...

You simply can not compare buprenorphine to full agonists and binding affinity does NOT mean it produces a proportionate level of mu agonist effects... far from it actually. Buprenorphine's mu agonist effects max out at an equivalent of about 30mg of methadone... you can take as much bupe past this point (which, for most people, is between 2-4mg) as you want, but it won't have stronger opioid effects and likely won't hold you any better.

The 32mg is not a ceiling effect or anything, its just the maximum dose they found to have ANY therapeutic benefit although the vast majority of people do not get any superior effects at doses over a couple milligrams. The multiple incarnations of this thread repeatedly attest to this.

IndustrialStrength said:
I just wanted to mention that catcalls is actually being realistic.
I was going to post myself but I didn't want to make dpc feel bad.
But seeing as someone else pointed it out I figure I might as well toss my experiences in as well
I've been doing .5mg to 1mg a day & still get significant w/d's if I try to come off it.
I just didn't want to ruin dpc's happy thoughts.

Though if dpc is one of the lucky one's he might be able to jump off pretty easily as I've seen some people do so.
I sadly enough am not one of those people as jumping off even at .5mg is very unpleasant for me.

Regardless please don't draw me into any in-fighting or bickering. :)
I'm just posting to add my 2 cents that not everyone can jump off at that dose & get away easily.
Some of us need to go even lower.
Hell I jumped once at .25mg a day & still had mild to moderate w/d's.

Either way best of luck to you dpc!
Also congratulations on doing well on your taper.
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^this, this, this and oh yeah, this!

You bring such a balanced, level-headed and knowledgeable perspective to this thread and the rest of OD and its great to have you around.
 
IndustrialStrength said:
^^ Very well stated JB.
We don't always agree but in this particular case you said what I was thinking very well.
Thanks for your post.
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I rarely "dont agree" with someone.....i understand that everyones different and has different opinions.....and im not one to consider one opinion better than another unless one has actual facts to back it up.....but my point is, sometimes people think im disagreeing with them, when in fact, im just trying to post another point of view...which most people dont like to hear. or they think its startin an argument which i have never in my life tried to do on purpose.
anyway, guess i was just sayin I have never thought that we "dont always agree" cuz i respect mosts peoples opinions and thoughts but I can see where one might become confused about that since most people are different than me.
 
jamesBrown said:
I rarely "dont agree" with someone.....i understand that everyones different and has different opinions.....and im not one to consider one opinion better than another unless one has actual facts to back it up.....but my point is, sometimes people think im disagreeing with them, when in fact, im just trying to post another point of view...which most people dont like to hear. or they think its startin an argument which i have never in my life tried to do on purpose.
anyway, guess i was just sayin I have never thought that we "dont always agree" cuz i respect mosts peoples opinions and thoughts but I can see where one might become confused about that since most people are different than me.
Click to expand...

Actually that's along the lines of what I was saying. :)
I find it great that there are multiple points of view being brought up.
Having multiple points of view helps encourage discussion & allows for more knowledge to be spread in the long run.
So I just wanted to say thanks for continuing to do so.
You can't have a proper discussion if it's all one sided.
I'm glad to see how well this thread & other discussions are going as of late.

@Cane2theLeft

Thanks for the compliment.
I've been posting again more as of late & I'm happy to see that others find it helpful.

Either way I'm happy to see how well BL & this thread in particular are working out & spreading the message of Harm Reduction.
Let's all work together & keep up the great work! :)
 
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