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Bupe Suboxone/Buprenorphine FAQ & Megathread v3; 2010 - 2022

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I just took my last line of smack (hopefully ever), and am now counting down the hours until the wd's set in. Tomorrow at 9 AM(14 hours from now) the sub clinic opens, and I will be there anxiously waiting like a teenage boy in line for his favourite rock band.

Love that you're keeping your humor. At least so far... :):)
 
Yeah, I think I'm done with drinking. For good this time. Then again i always say that after getting hammered. Not because it sucks so bad, because it really isn't terrible. It's just not great. I'd choose alcohol over say, a piperazine any day. But I'd choose sobriety over alcohol, which is saying something. Too bad this mindset will only last for a few months like it always does.

I'm fuckin' pissed about my laptop though. I was just considering buying turntables and a mixer n shit, though i can't really afford to buy my music collection on vinyl on top of that so i was planning on using mp3's/CD's which means i sort of need my computer. I might even need it for vinyl too not sure. Oh well. Maybe I'll still have enough money after getting my screen fixed, i do have insurance i just don't know if i have the retard insurance.

At least it's not a mac though, apple insurance omits 'Act's of God' from the criteria for getting something fixed. God strikes down your ipod with lightning? Sucks to be you, because apple doesn't cover it. Literally, read the warranty.

[On-topic]
Anyway, It was christmas and i had been out of kratom for almost 48 hours so i just took some suboxone. My first priority is to buy enough kratom for like a month so i don't have to deal with this again, because a week and a half on kratom wasn't long enough i felt like shit all day and didn't fall asleep until 6am, almost missing christmas haha. Good thing Christmas is the only time of year i get money from my family, since they never know what to buy me. Otherwise i would be totally fucked what with my laptop and needing kratom. Edit - I did roughly a mg or so and i have a nice buzz going on for like the first real time since getting on suboxone, sweet. I couldn't resist, being christmas and all. Fuck withdrawing on christmas... I don't even care if it's a minor set back. like i said i have cash now so I'll be investing in more kratom and some klonopin in a couple days time, so it will be a hell of a lot easier to go the whole length of withdrawal without caving. Plus I'm in jersey right now so i can't get dope in like 3.2343 seconds flat. Back in illinois i can't, so it's not a bad thing that i used bupe anyway. I'd rather not risk buying heroin and fuck up my detox completely.
[/On-topic]

Anyway I'll stop ranting again. I ramble too much when i haven't been posting a lot.

You're in Jersey and can't get dope in 3.2343 seconds flat? Where the hell are you going to get such quick service? LOL.

Anyways I completely understand not wanting to go through withdrawals during Christmas - that's understandable. That's what I did 2 Xmas' ago. :| Utterly horrible.

Love that you're keeping your humor. At least so far... :):)

Yeah I lol'd too. =D What a good comparison.
 
Even my opiate-naive gf felt a difference when snorting 1 mg Suboxone last night, compared to 1 mg of Subutex a few times before. I'm very sensitive and without being heavily opiated, these senses come back and i'm very aware of them. The effects of the Suboxone is different than the Subutex, saying it for sure now IME. If i'm going to taper down to 0.2 and crazy little amounts like these to say the final goodbye to opiates after 10 years, i want to do it with my dear Subutex. Of course it's not a matter of orange flavor (that i freakin' hate) as i had mentioned before, but differences became visible yet still can't word them. But, with yesterday's gf observation, and a few months back when i gave my younger cous some Suboxone to use while trying to quit H, it was the 3rd time, only that the first 2 times, i had given him Subutex that he loved; Even the young fella noticed a difference and wasn't too happy; Of course i tried to convince him that Buprenorphine is the same in both, and that it's a mental thing, while i wasn't convinced myself!
Simply..if they were exactly the same and had the same effects, they would have the same name, but they are different drugs and i feel this difference more than ever now, but as i said, i still can't word them. Maybe will do a research myself about the different effects of Subutex and Suboxone :)

Found a Sub/Plugging thread...very interesting to read.

Happy Holidays everyone
 
It's day 11 and I still woke up feeling kinda achy...

Took like 1 MG. Hoping to stay on this for 2 more days, and then just taking little tiny pieces every once and a while.

How come I'm still feeling W/Ds after 11 days off OCs?

any ideas?
 
^You didn't give us enough information really to tell you. Hoe long were you on OC for? Where did the bupe come into play, as this is a bupe thread... Etc, etc...
 
Even my opiate-naive gf felt a difference when snorting 1 mg Suboxone last night, compared to 1 mg of Subutex a few times before. I'm very sensitive and without being heavily opiated, these senses come back and i'm very aware of them. The effects of the Suboxone is different than the Subutex, saying it for sure now IME. If i'm going to taper down to 0.2 and crazy little amounts like these to say the final goodbye to opiates after 10 years, i want to do it with my dear Subutex. Of course it's not a matter of orange flavor (that i freakin' hate) as i had mentioned before, but differences became visible yet still can't word them. But, with yesterday's gf observation, and a few months back when i gave my younger cous some Suboxone to use while trying to quit H, it was the 3rd time, only that the first 2 times, i had given him Subutex that he loved; Even the young fella noticed a difference and wasn't too happy; Of course i tried to convince him that Buprenorphine is the same in both, and that it's a mental thing, while i wasn't convinced myself!
Simply..if they were exactly the same and had the same effects, they would have the same name, but they are different drugs and i feel this difference more than ever now, but as i said, i still can't word them. Maybe will do a research myself about the different effects of Subutex and Suboxone :)
Found a Sub/Plugging thread...very interesting to read.

Happy Holidays everyone

Actually, the difference between suboxone and subutex is that suboxone contains both buprenorphine and naloxone while subutex only contains the buprenorphine. The naloxone was put in the suboxone so it could get a more lenient schedule rating(schedule V in some states and schedule III in others).....this helps it get to the public easier. It has been discussed extensively here on BL and probably in this very thread(and in all the previous megathreads).
They say the naloxone blocks users from snorting or injecting the suboxone but we all know that is completely false. So the question becomes..."what effects, if any, does the naloxone have on someone in comparison to subutex".
The majority say it has no effect, but some people swear that they feel a difference between the two drugs, subutex and suboxone. Now, its very possible that this is just a mental issue and there really is no difference(much like the placebo effect), or it could be possible that a small percentage of the population are actually hypersensitive to naloxone and can feel effects from it that others cant, even when taken in the small doses that are in suboxone.
Since there has been very little research on this exact subject, all we can do is speculate....but for the most part we do know that the naloxone bears no effect in comparison to buprenorphine taken without naloxone....so for right now we can say conclusively that the chances of suboxone having a different effect on you then subutex is very slim. But if you are one of those people who seems to feel a difference, which is usually negative, I feel sorry for you.
 
Just wanted to see what everyone thought and let you know how I'm doing.

I switched from alot of Oxymorphone to Suboxone, all of this from being in Pain Management, etc... I was looking for my Suboxone to replace the OM as a treatment for pain, which it has, at about 60% the efficacy.
I have also lapsed in and out of moderate depression, so I wanted to see about the anti-depressant properties of Bupe that have been coming out of clinical trials.

As far as my treatment is going, I've been on for nearly a month, and have no cravings and haven't had the desire to go find other opiates for pain relief, but I would like to get a little buzzed once in a while (I'll get to that later).

In the first few weeks I experienced SEVERE depression, as bad as I've ever had it in my life, and there was no obvious reason for this for the first time, so it bothered me quite a bit. In the last week or so, it has been getting somewhat better.
Could the Naloxone be causing the depression? Do you think it is just PAWS from years and years of using an extremely potent opiate?

Alright, now, when I first started my subs i had been off OM for like a week cold turkey, when I first was on it, I would grab a nod once in a while which was really nice. It also gave me better analgesia. With time, that has decreased, and I find it hard to grab any type of significant pain relief from the subs anymore, but it is working well for the inevitable opiate cravings, although mine are slightly different because they come from a desire for pain relief.

So, what can I do to potentiate the euphoric and analgesic effects of the bupe?

I tried searching around quite a bit, but only came up with IV techniques, things that weren't really applicable. I imagine that there is an antihistamine/ antacid/ allergy drug that is compatible with bupe. Although I'm really unclear on how the norbuprenorphine interacts with your body and these potentiators, so if anyone has advice for me, it would be greatly appreciated.

I'm not just "trying to get high" I'm trying to extend the analgesic and antidepressant effects of the suboxone.

Thanks for the replies, hope everyone's holidays are going well and everyone is good on their path of treatment.
 
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Just wanted to see what everyone thought and let you know how I'm doing.

I switched from alot of Oxymorphone to Suboxone, all of this from being in Pain Management, etc... I was looking for my Suboxone to replace the OM as a treatment for pain, which it has, at about 60% the efficacy.
I have also lapsed in and out of moderate depression, so I wanted to see about the anti-depressant properties of Bupe that have been coming out of clinical trials.

As far as my treatment is going, I've been on for nearly a month, and have no cravings and haven't had the desire to go find other opiates for pain relief, but I would like to get a little buzzed once in a while (I'll get to that later).

In the first few weeks I experienced SEVERE depression, as bad as I've ever had it in my life, and there was no obvious reason for this for the first time, so it bothered me quite a bit. In the last week or so, it has been getting somewhat better.
Could the Naloxone be causing the depression? Do you think it is just PAWS from years and years of using an extremely potent opiate?

Alright, now, when I first started my subs i had been off OM for like a week cold turkey, when I first was on it, I would grab a nod once in a while which was really nice. It also gave me better analgesia. With time, that has decreased, and I find it hard to grab any type of significant pain relief from the subs anymore, but it is working well for the inevitable opiate cravings, although mine are slightly different because they come from a desire for pain relief.

So, what can I do to potentiate the euphoric and analgesic effects of the bupe?

I tried searching around quite a bit, but only came up with IV techniques, things that weren't really applicable. I imagine that there is an antihistamine/ antacid/ allergy drug that is compatible with bupe. Although I'm really unclear on how the norbuprenorphine interacts with your body and these potentiators, so if anyone has advice for me, it would be greatly appreciated.

I'm not just "trying to get high" I'm trying to extend the analgesic and antidepressant effects of the suboxone. Thanks for the replies, hope everyone's holidays are going well and everyone is good on their path of treatment.

to potentiat the "euphoric" effects of bupe, you need to be on a dose lower than 2 mg's and stay at that dose for a long while(maintain at that dose). higher doses will have more antagonistic properties that tend to block any chance of getting any euphoric effects. The low doses seem to be MUCH more beneficial than high doses.
I didnt need some extra drug to potentiate my subs euphoric effects, I just needed to maintain on 0.5 mg doses and enjoy the euphoria. Anytime I increased the dose or mixed anything up, I got less euphoria. So thats my experience, and if you try it, i hope it works for you.

*FYI, you would be immensely suprised at how little amount of subs you need to make sure your not sick. Alot of doctors put you on these high doses that your body becomes dependant upon, so then the person thinks they need a high dose to feel OK, when the truth is, they just need to be weaned off this rediculously high dose to something MUCH smaller as I explained, and learn how to maintain on these small doses. It may mean you might have to dose more then once a day but I think thats a small price to pay for the euphoria you get. And I dont think the euphoria is another addiction because it kept my cravings away and allowed me to enjoy the benefits of suboxone while not being addicted to them.
 
I'm sorry, I should have been more clear. I've been taking NO MORE than 1.5-2mg sublingually (so .5-.67) into the bloodstream.

Would you say to stick to around .5 sublingual or .5 after taking into account BA differences? i.e. you shoot .5 for 100% BA or you take 1.5 sublingual for 35%BA = .5 absolute dose.

I took the advice of people here to not go too high, and when my Dr. started me (I was on 30mg OM a day which isn't huge) he told me to take 24mg a day!!! that is crazy. I've only gone up to like 3 max.
 
I'm sorry, I should have been more clear. I've been taking NO MORE than 1.5-2mg sublingually (so .5-.67) into the bloodstream.

Would you say to stick to around .5 sublingual or .5 after taking into account BA differences? i.e. you shoot .5 for 100% BA or you take 1.5 sublingual for 35%BA = .5 absolute dose.

I took the advice of people here to not go too high, and when my Dr. started me (I was on 30mg OM a day which isn't huge) he told me to take 24mg a day!!! that is crazy. I've only gone up to like 3 max.

im sry man but i forgot to mention that if your taking it sublingually, the chances of obtaining euphoria go down ALOT(as in ive never heard of an opiate tolerant person getting euphoria from SL dosing of sub, or any ROA thats not IV). I use to IV my subs so thats why I could get a high easier.... I was getting all the sub into my bloodstream all at one time.

Im sry but I cant really help you get euphoria when your dosing SL. I just dont think its possible unless maybe you take atleast a 2 day break from the subs and then dose again......that next dose may feel better then average...possibly(ony possiby) giving you some euphoria. But im not promising anything.
 
Suboxone doesn't give a very strong euphoria for most people after a little while. I've been on and off of it so many times just for this reason.
 
Actually, the difference between suboxone and subutex is that suboxone contains both buprenorphine and naloxone while subutex only contains the buprenorphine. The naloxone was put in the suboxone so it could get a more lenient schedule rating(schedule V in some states and schedule III in others).....this helps it get to the public easier. It has been discussed extensively here on BL and probably in this very thread(and in all the previous megathreads).
They say the naloxone blocks users from snorting or injecting the suboxone but we all know that is completely false. So the question becomes..."what effects, if any, does the naloxone have on someone in comparison to subutex".
The majority say it has no effect, but some people swear that they feel a difference between the two drugs, subutex and suboxone. Now, its very possible that this is just a mental issue and there really is no difference(much like the placebo effect), or it could be possible that a small percentage of the population are actually hypersensitive to naloxone and can feel effects from it that others cant, even when taken in the small doses that are in suboxone.
Since there has been very little research on this exact subject, all we can do is speculate....but for the most part we do know that the naloxone bears no effect in comparison to buprenorphine taken without naloxone....so for right now we can say conclusively that the chances of suboxone having a different effect on you then subutex is very slim. But if you are one of those people who seems to feel a difference, which is usually negative, I feel sorry for you.



Well, the majority say the naloxone has no effect, but it IS there, and since i'm feeling the difference between the Subutex and the Suboxone, then this difference is caused by the naloxone. Just trying to reach a rational explanation for my light headaches and while researching the mighty world wide web, i came across "Suboxone headaches" as the title of my search, need to do more reading about that. In my situation, the Subutex was great then when the douchebag Dr. wrote Suboxone by mistake and i had no option but to take them till my next refill, I started to get those headaches, and no it's not an allergy but it's my body telling me something for sure and this is not the 1st time and not only me! I need a study or 2 or 3 about this :\
 
I'm sorry, I should have been more clear. I've been taking NO MORE than 1.5-2mg sublingually (so .5-.67) into the bloodstream.

Would you say to stick to around .5 sublingual or .5 after taking into account BA differences? i.e. you shoot .5 for 100% BA or you take 1.5 sublingual for 35%BA = .5 absolute dose.

I took the advice of people here to not go too high, and when my Dr. started me (I was on 30mg OM a day which isn't huge) he told me to take 24mg a day!!! that is crazy. I've only gone up to like 3 max.

Snorting or plugging the suboxone increases the euphoric effects.

Taking it only once a day, in my experience, also increased the euphoric effects.

But the sub "high", at least for me after years of use, was a little 45min opiate mood lift. Nothing dramatic. But the mood lift from taking suboxone was the same after four years. After the first little period, tolerance seems to remain unchanged.
 
If anyone has a study about Naloxone and headaches/ body aches/ depression, I would love to see them. I actually have a great doctor and we've reviewed some of the Harvars studies about bupe and depression, etc... and he is super receptive to these kind of things, but i'd like to go in with some concrete research.
 
Well, the majority say the naloxone has no effect, but it IS there, and since i'm feeling the difference between the Subutex and the Suboxone, then this difference is caused by the naloxone. Just trying to reach a rational explanation for my light headaches and while researching the mighty world wide web, i came across "Suboxone headaches" as the title of my search, need to do more reading about that. In my situation, the Subutex was great then when the douchebag Dr. wrote Suboxone by mistake and i had no option but to take them till my next refill, I started to get those headaches, and no it's not an allergy but it's my body telling me something for sure and this is not the 1st time and not only me! I need a study or 2 or 3 about this :\

I noticed absolutely no change when I went from bupe to sub. I was insufflating both. My guess is there's a small population of users who are susceptible or overly sensitive to naloxone.
 
tramadol + bupe

alright so ive been in bad opiate withdrawal for 3 days or so... i dont see my pain doctor until new years eve... the pain + the withdrawal has taken a lot out of me... ive been taking tramadol for the past 3 days seeing as i dont have any opiate connects anymore... its helped in that im not having most of the major symptoms like cold sweats, rls, etc... mostly just runny nose, anxiety/insomnia, and about to shit myself every other minute...

anyway i randomly came across an 8mg suboxone... i researched and found that the tramadol i took a few hours ago would not throw me into precipitated withdrawal along with the bupe... so i went ahead and took 2mg of the bupe.

its been 30 mins and im confused... i dont feel better at all im still ab to shit myself... ive never actually taken bupe and from what ive read 2mg should be enough.

any info would help thanks... btw im coming off of ab ~80mg/day oxymorphone IV habit or about 150mg/day insufflated oxymorphone... i never IV and snort on the same day i do either i feel like.
 
did u take the sub under the tongue? or what? if you did, it can take upto an hour or more to kick in. or it might just not have been the right dose
 
^ i would have but i snorted it b/c of the higher bioavailability, like 50% vs 30% sublingually... i just want to make it last as long as possible.

honestly if i was home i would have IVed it but im in so much pain and discomfort and at a friends house where its not possible so i went ahead and snorted some... i dont want to do too much more id rather not waste it by accidentally doing too much and rather just wait til i can IV some... im feeling "slightly" better now actually.

if i were to IV bupe over the next couple of days what is a good dose to follow??

after doing another 1mg, making a total of 3mg, i noticed a slight change in my comfort so im assuming im just slightly under-dosed.
 
Hmm you should def feel it by now if you snorted it. I IV my bupe everyday and only need about .2-.5mg per shot to feel 100% for at least 6-8 hours. So i would def try that . You can make that sub last a long time doing this .
 
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