Bupe Suboxone/Buprenorphine FAQ & Megathread v3; 2010 - 2022

[geraggh34]

Can I call around and just ask doctors if they are willing to write generic tex? I have no insurance and I just can't afford suboxone. Right now I'm just getting them from the street but want to cut the bullshit and just get a doc I've been good stayin off dope and on bupe. I finally just put te needle down after a quick affair with coke so when I heal up I can just say I wasn't an IV user(since doctors seem to think you can't slam oxone)

EDIT stupid iPhone correcting suboxone to sub ozone lol

 

[Fire&Water]

Can I call around and just ask doctors if they are willing to write generic tex? I have no insurance and I just can't afford suboxone. Right now I'm just getting them from the street but want to cut the bullshit and just get a doc I've been good stayin off dope and on bupe. I finally just put te needle down after a quick affair with coke so when I heal up I can just say I wasn't an IV user(since doctors seem to think you can't slam oxone)

EDIT stupid iPhone correcting suboxone to sub ozone lol

Dont expect it to be inexpensive if you live on the left coast...

 

[geraggh34]

TN. Not expecting to to be cheap but I may as well get on methadone if I have to pay 6 or 700 bucks a month

 

[sxeandpure]

I have a habit of about 2 bags (roughly 200mg) of heroin IV'd daily. I only have access to 8mg sublingual tablets. Are those too strong for someone with my habit? I want something that will alleviate withdrawal symptoms, but I feel like 8mg is way too much and that I might be better off quitting cold turkey. Any insight?

 

[Donewthislife]

I have a habit of about 2 bags (roughly 200mg) of heroin IV'd daily. I only have access to 8mg sublingual tablets. Are those too strong for someone with my habit? I want something that will alleviate withdrawal symptoms, but I feel like 8mg is way too much and that I might be better off quitting cold turkey. Any insight

Um....you can break them in half and that will be 4mg. And then you can break the halfs in half and that will be 2mg. Is that simple enough?

Try quitting CT. If you can stand the wds then just take a small amount and wait an hour or so. If you feel okay then stick to that dose and taper from there. You can find various tapers in this thread.

 

[sxeandpure]

Ah, didn't even think about breaking the pill. I've heard 2mg is good starting dose, so I'll try that and increase if necessary.

 

[GOYA]

Hi BL. A friend of mine mentioned this site to help me better understand Suboxone and here I am. I'm just at a crossroads on what I should do and hopefully some of you can help me.

I have been struggling with addictions for most of my life. I am in my early 40s. I started fooling around with Oxycodone a while ago and found myself in two rehabs the last three years. I tried to stay off Oxys, but would only last around three months and then I would relapse for a few days. That was my MO for the last year. I saw a shrink and he mentioned Suboxone to me and said I maybe should give it a try to help with my depression as well as my constant relapses. I at first balked at the idea since I've heard of many horror stories of people trying to come off of subs. I then relapsed again on Oxys and decided to go on Suboxone for a short term taper. It is now day 24 on subs. I started with 4mg the first two days on subs and then decreased to under 2mg a day. It has helped me with my cravings for opiates substantially. It has also helped tremendously with my depression. I do not feel high at all. It has helped me tremendously with those two important areas of my life but, all I can think of is when I do come off subs how hard it's going to be for me. I know it sounds nuts. I just dont know if I should continue on the low dose and worry about getting off when the time comes, or just get off these asap? And if I get off asap, would my PAWS be somewhat manageable or will it be like the horror stories I hear about.

 

[StartedHydro]

Why do you have to come off sub? I always wonder why its a general way of thinking, that one HAS to ween of Sub(opioiods)? For those of us who have self medicated throughout life and finally found relief in some fashion from opiates/opioids, why cant we just stay on a dose thats right for the person. I also have found it strange that if I saw my primary care doc and said I hurt my back may I have a few days supply of *opioid* of choice, its like pulling teeth, but if I see my Sub doc he will give me BUTT loads of sub no questions asked. Its funny to me... cant have opiates for legit issue but known abuser here take 60 8mg sub pills.

Anyways, I have been on sub for a long time and it helps my adhd, mood, energy levels, sense of well being, keeps me straight... so if sub does all these wonderful things what is the harm in staying on it for life? Its a brilliant opioid... in that it has a very long lasting duration, steady state of med in blood less prone to fluctuations(up and down mood swings), kappa rec ant-ag for depression reflief, very safe profile over dose related, stops cravings, if one does truly want off is tapered correctly relative to a full ag its not bad at all.

I just wish opiates were viewed in a more positive light, as they are truly a miracle substance.

 

[GOYA]

Thank you for responding. My shrink kinda feels the same way about being on subs. (He doesn't charge me for office visits since he knows I am not working) When I went to him for my depression issues that's when he mentioned subs to me. I have tried Lexapro, Lamictal, Prozac, Paxil, Wellbutrin, Tegretol and have relapsed on all of them. All they have done is made me not feel ANYTHING. At least when I am on subs I can feel feelings. At least with subs I want to get out of bed, look for work, take a shower and do things to better myself. I couldn't do that on any antidepressant they had ever prescribed me. I have thought about being on subs long term, I just have never heard of anyone staying on them for a very long time and wondered why people were coming off subs myself. Is it just societies stigma (if that's the proper term) of being on subs long term the reason why people decide to come off subs, or are there any side effects from long term use? You would think that if something saved a persons life from years of misery that they wouldn't want to come off subs.

Also, how long have you been on subs?

 

[StartedHydro]

I have been on Sub now for about four years. Sub to me is as blood pressure med is to someone with high blood pressure. While on sub I am by all accounts normal. When I come off sub is when shit hits the fan. I will be on opiates/opioids for my entire life, and nothing is wrong with that. I think as we grow and learn from our mistakes "addiction" takes a back seat to dependence/maintaince.

I am a huge believer in any substance that is "earthly" and not toxic in the body should not be made illegal. If Alch and smokes are legal opiates at the very least should be.

 

[StartedHydro]

I cant seem to find a few answers to some questions I have. First of as has been stated many times before, pills are not meant to be IVed. One carries great risk in regards to their health IVing pills. I take every precaution I can in this regard, with that in mind.... I have noticed I feel the effects of bupe more the highs and the lows. I know when IVed its basically 100% BA and I do 1mg around 5:30 and another 1mg around 3:30. Do I notice the ups and downs due to IVing or because im below the celiing dose and bupe is acting as a full agoinst now? Half life of a substance is a constant, yes... no... regardless of ROA? If IVing the bupe is processed faster because its active faster than say Sublin?

Im confused as I hear reports that if IVed bupe has a shorter duration, cleared from body faster.....

and the ups and downs is that from being below the ceiling dose or because Im IVing?

Thanks to anyone who can help me understand whats going on a little better.

 

[Znegative]

Well, you are basically around the cusp of the cieling effect. At 100% BA, buprenorphine's cieling is somewhere around .5-1mg. Also the reason that the duration is shorter, is that your body does not start elliminating a drug until it has reached its peak plasma concentration. When you take bupe through another ROA, say sublingual, this can mean that it would take about four hours before the body actually begins the slow process of eliminating buprenorphine from your system (because remember, it's got a very long half life). However, when you IV bupe, you peak within 10-15 minutes, and then begin to metabolize the buprenorphine almost right away, which is why the duration feels so much shorter.

This whole concept baffled me for a while, but the half life does not change depending on ROA, all that changes is how quickly the body begins to eliminate the substance.

So in conclusion, yes IV bupe does have a shorter duration especially if you are Dependant on it.

 

[StartedHydro]

Ahhhh....

I never knew that your body starts elliminating a substance until peak plasma.

So it could be two things at play with why I am feeling the ups and downs more so than before. One, its being cleared faster due to ROA, and Im subject to the peaks and valleys of dosing being below the ceiling?

 

[i are spectre]

body should begin elimination when substance comes in contact with enzymes, not after the peak.

ceiling dose is different for everyone and there aren't many ways to actually quantify that. several times i have dosed far above what people consider a ceiling dose and noticed some nice effects. the price is what stops me from constantly doing that. i recall nodding off in ochem lecture from suboxone alone.

GOYA: many people stop or try to ween off suboxone because of side effects either directly from the drug or other psychological reasons, for instance being on it for several years and dishing out all that cash you may find yourself upset at times, perhaps when you have to decide between your suboxone strips or if you want to eat that day. if cash isnt a problem then just being stuck on a drug can have some negative psychological effects ya.

cire: you can pm me if you'd like

 

[jkool702]

So I have a question (I'm new here so I'm not sure if this is the correct place to post this or not).
My basic understanding after reading a number of posts here is that for another opiate (say heroin) to break through the bupe you need to have 1-2 mg bupe or less in your system. I understand the whole 36 hour half life for bupe. My question is does that 1-2mg tolerance for other opiates to break through depend on route of administration. Say I took 8mg then 36 hr later 4 mg (both sublingually) would I have a total of 8mg bupe in my system (the 1st 8mg went through 1 half life and is now 4 mg) or would I have 8/3 mg bupe in my system, because the bioavailability of bupe sublingually is ~30%. and I suppose another question is is this 1-2mg tolerance of bupe in your system to break through based on IV'ing bupe (100% bioavailability) or sublingually taking bupe (~30% bioavailability)? I know everyone's chemistry is different but I'm jus looking for general aqnswers / suggestions. Thanks!

P.S. I've read that taking St. Johns Wort increases the enzyme in your system that breaks down bupe, removing it faster (effectively decreasing its half life). Can anyone confirm this? And if so can anyone (estimate) what the new half life of bupe would be if your taking St. Johns Wort? Thanks again!

 

[BPotter]

I have been on suboxone before and it worked wonders for me and i never had any issues with precipitated withdraws. I decided to get back on track and get clean so i waited 24 hours after my last use and did the cows test with a 26. I made sure I was good and sick because I have heard the horror stories of pwd's With in 15 minutes of taking the 1 mg of suboxone I was starting to feel pretty horrible. Within the next 15 minutes I was absolutely sicker then I could even imagine was possible. Man the horror stories are true. I had to leave work and try to get myself together, I ended up having to do a little opiate I knew it wouldn't get me buzzed but it definitely made life better. I would rather go 3 days cold turkey then 2 hours of precip withdraw. My question is tomorrow will I have an issue inducing suboxone or should I be ok because the suboxone that got on my receptors today? I am scared to even take it now fearing that would happen even after waiting a long period of time and making sure I had a high cows score. How long should I wait before trying again? Any helps or comments would be greatly appreciated.
Thanks
Harry

 

[MissyJane]

Suboxone film dosing through eye. I have never posted before in my life but I can't find an answer anywhere. Recently, I have seen people put there suboxone film dose directly into their eye. I was told that you put A quarter in at a time. Feel the effects the best this way. I wasn't too know anyone elses experience with taking it this way. Please explain in detail.

 

[Captain.Heroin]

Suboxone film dosing through eye. I have never posted before in my life but I can't find an answer anywhere. Recently, I have seen people put there suboxone film dose directly into their eye. I was told that you put A quarter in at a time. Feel the effects the best this way. I wasn't too know anyone elses experience with taking it this way. Please explain in detail.

Please don't do this; this isn't safe.

 

[Droppersneck]

Suboxone film dosing through eye. I have never posted before in my life but I can't find an answer anywhere. Recently, I have seen people put there suboxone film dose directly into their eye. I was told that you put A quarter in at a time. Feel the effects the best this way. I wasn't too know anyone elses experience with taking it this way. Please explain in detail.

Jesus christ. Please dont do this!

Your vision>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> a better glow

Also it doesnt actually work

 

[Tommyboy]

So I have a question (I'm new here so I'm not sure if this is the correct place to post this or not).
My basic understanding after reading a number of posts here is that for another opiate (say heroin) to break through the bupe you need to have 1-2 mg bupe or less in your system. I understand the whole 36 hour half life for bupe. My question is does that 1-2mg tolerance for other opiates to break through depend on route of administration. Say I took 8mg then 36 hr later 4 mg (both sublingually) would I have a total of 8mg bupe in my system (the 1st 8mg went through 1 half life and is now 4 mg) or would I have 8/3 mg bupe in my system, because the bioavailability of bupe sublingually is ~30%. and I suppose another question is is this 1-2mg tolerance of bupe in your system to break through based on IV'ing bupe (100% bioavailability) or sublingually taking bupe (~30% bioavailability)? I know everyone's chemistry is different but I'm jus looking for general aqnswers / suggestions. Thanks!

I believe that I answered this in the other thread you asked it in, but again, the 1-2mg dosage mentioned is with sublingual administration. Generally Suboxone dosages mentioned here are always in respect to sublingual administration unless it is specified otherwise. My guidelines are 1mg and under wont really block anything, 2mg blocks for a day, 4mg blocks for 2 days, and 8mg blocks for 3 days. If you take it daily for maintenance then you should add 1 day onto each amount of time I mentioned. After 48 hours you will usually feel some effects, but 3 days or when you are in moderate to severe withdrawals is when you should feel almost full effects. When I was maintaining on 8mg + a day it took 4 days to get a proper high, and wasn't really worth the sickness I put myself through, especially if I only waited 3 days.

I have been on suboxone before and it worked wonders for me and i never had any issues with precipitated withdraws. I decided to get back on track and get clean so i waited 24 hours after my last use and did the cows test with a 26. I made sure I was good and sick because I have heard the horror stories of pwd's With in 15 minutes of taking the 1 mg of suboxone I was starting to feel pretty horrible. Within the next 15 minutes I was absolutely sicker then I could even imagine was possible. Man the horror stories are true. I had to leave work and try to get myself together, I ended up having to do a little opiate I knew it wouldn't get me buzzed but it definitely made life better. I would rather go 3 days cold turkey then 2 hours of precip withdraw. My question is tomorrow will I have an issue inducing suboxone or should I be ok because the suboxone that got on my receptors today? I am scared to even take it now fearing that would happen even after waiting a long period of time and making sure I had a high cows score. How long should I wait before trying again? Any helps or comments would be greatly appreciated.
Thanks
Harry

If you got any sort of buzz when you took the opiates after precipitated withdrawal then you will still be at risk for them again, but I would imagine that you would be alright to dose at the 24 hr mark this time. Start with 1mg again after maybe 30 hours, and see how it effects you.

Suboxone film dosing through eye. I have never posted before in my life but I can't find an answer anywhere. Recently, I have seen people put there suboxone film dose directly into their eye. I was told that you put A quarter in at a time. Feel the effects the best this way. I wasn't too know anyone elses experience with taking it this way. Please explain in detail.

Unless your mouth and ass are sewn shut, I would strongly advise against this. But if that's the case, taking Suboxone would be the least of your worries.