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Bupe Suboxone/Buprenorphine FAQ & Megathread v3; 2010 - 2022

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cire113 said:
It took me 16mgs subingual sub(only about 30 % from absorption rates)for my first day from 6 day relapse to kill most of withdrawals...
When your habit is crazy large taking more sub up to 16 or 24 Definetly more is more up to a point also


My normal maintenance dose was 4-6;

.5 Xanax every 4 hours and vaped indica bud


Feel not too bad but I expect to take 2-3 days to feel much better

I still feel some very very minor Wds the first 72 hrs switching back to sub as body balances out tolerance

Wonder how I'll feel by Sunday
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I'm so glad to hear you're back on Suboxone man. :)

I'm very proud of you.
 
Mr.Scagnattie said:
I agree with Captain. You seem to be getting loaded on the bupe... so clearly your habit wasn't really big enough to warrant that dose. Take less and see how you feel. If you don't need bupe... don't take it because it just leads to even more problems.
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Is being tired and looking doped up typical of being on subs? Do most people start falling asleep in the middle of the day and have huge dark circles under their eyes?
 
DoUbLeYoU said:
Is being tired and looking doped up typical of being on subs? Do most people start falling asleep in the middle of the day and have huge dark circles under their eyes?
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No that's not typical. That's a sign of being on way too much suboxone and not needing it. It's not supposed to get you high... it's supposed to take away your withdrawals and get you back to normal.

That response is typical of somebody with no opiate tolerance who is using suboxone to get high.
 
Ive taken subs for 4 days and I now feel the energy that people talk about. I havent had the sick feelings that a loy of people have, of which im amazed because I really dont have a terribly high tolerance to opiates. However I have taken a lot of vicoden lately ( up to 40 Mg at a time)
 
So I posted a couple days ago about how bad the wd's were but I think the flu or whatever I had made it way worse.

It's been about 6 days now since my
Last dose and I feel about 60%. I am still cold and anxious, The odd hot flash and a bit of restlessness. Was finally able to do some exercise today. I also slept about 10 hours yesterday.

My flu still isn't gone yet so hopefully in a couple days I'll be a lot better. Just taking Tylenol, Benadryl and 2-4 immodiums a day
 
alcoholic333 said:
So I posted a couple days ago about how bad the wd's were but I think the flu or whatever I had made it way worse.

It's been about 6 days now since my
Last dose and I feel about 60%. I am still cold and anxious, The odd hot flash and a bit of restlessness. Was finally able to do some exercise today. I also slept about 10 hours yesterday.

My flu still isn't gone yet so hopefully in a couple days I'll be a lot better. Just taking Tylenol, Benadryl and 2-4 immodiums a day
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Damn. Rough deal having to go through the flu and withdrawals, man. Glad you're feeling better though. The fact you're getting some sleep is really important and the exercise helps a lot too. Keep it up and you'll be good to go in no time.
 
I started subs again today and the price is just fucking crazy def going to try and find a different doc. What I'm afraid of is taking subs for like two years then having to kick subs,,! Which sucks ass. I'd probably get some tramadol for the wds

Guess they hav, 0.5mg strips now

also subs seem to give me heartburn

at night?
 
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Something I've been curious about... has anyone experienced this shitty phenomena where you've taken suboxone, however are still in withdrawal, but then when using a full agonist, the suboxone still blocks most of it. So, how can bupe be on your receptors therefore blocking opiates but you're still sick? No matter what the bupe dose, shouldn't it be that if you're still sick, your receptors aren't filled and therefore it shouldn't block anything even if you took a decent amount?
 
Mr.Scagnattie said:
Something I've been curious about... has anyone experienced this shitty phenomena where you've taken suboxone, however are still in withdrawal, but then when using a full agonist, the suboxone still blocks most of it. So, how can bupe be on your receptors therefore blocking opiates but you're still sick? No matter what the bupe dose, shouldn't it be that if you're still sick, your receptors aren't filled and therefore it shouldn't block anything even if you took a decent amount?
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Bupe is occupying the receptors but will only give you X amount of stimulation compared to full agonist...

So if other agonists are providing you with let say 10 stimulation taking enough bupe will only occcupy around 5 but will fill up all the receptors...

If you take enough suboxone it will stop most of the withdrawal though; but during detox you may have to take upwards of 24mg a day
 
I'd take the "3 X bags" out of the post, in our area it's common knowledge the price of a bag, but to people from other areas they wont have much of a clue how much is in that bag. I would say 3 bags a day and then say how much each of those bags generally weighs. prices are pretty much off limits even if it's just a number with no indication of how much you get for that number.

I'm on subs but never tried dope on them until I got down to 4 mg a day which is where I'm at. getting to 4mg from 16 was a walk in the park, the only noticable difference is you have to be more dilligent about remembering to take your dose, since it doesn't seem to last as long. I break it up to 2mg at night and 2 mg in the morning. I ran out early one time and went from 16 to 3mg a day overnight, no withdrawals. it's the last 2 mg that you have to take your time with.

being on 4 mg I try to wait 18 hours after my last dose if I decide to do dope, and do half of a bag, around 150mg in a shot, and generally get high as hell, although not high to the point of worrying about od's. then I wait probably 15 hours and take a small 1mg piece of a sub to make sure I dont precipitate w/d's then another 1mg until I feel fine. not the best thing to be doing, but if you're going to do it you should do it right.
 
2. How long do you need to be off it in order to get the full effect of injecting opiates?
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Depends, it varies based on the individual, and your tolerance.

When I was doing the back and forth thing (I'm just on Suboxone now), I found I could use 2mg sublingual Suboxone in the morning, and do heroin at night and still get 100% of the high.

That's just my experience though.

It's better to taper off Suboxone nice and slowly and to not use full agonist opiates unless you have serious pain IMO.
 
the bags are always a little light, dope users don't usually have scales. and even if they do and find out theyre getting scammed 50mg or so dealers know they'll still call when nothing else is around.
 
From what I have heard, there are no difference. Again, this is only word of mouth but I have heard the brand Suboxones with naloxone in them are only to be able to market them, or so they are more easily able to market them. Getting them past whatever administration (FDA?) oversees that sort of shit.
 
bupe with naloxone will have a slightly lowered effect when injected, other than that the main purpose of adding naloxone to buprenorphine is the patent. since the patent for straight buprenorphine pills expired formulations of just buprenorphine became generic. in order to recapture the profits of selling a name brand drug the company added naloxone to the bupe, creating a new "drug", one that could be sold for a few years without a generic equivellent. since drug designers invest billions into developing drugs, and the patent life is there to ensure companies get their investment back and turn a profit before a generic comes out. but pharm companies take advantage of this law by slightly changing the drug. in the case of suboxone tablets when they first came out it was adding naloxone, when the patent expired they simply developed a sublingual film and are currently phasing out the pill. because of kick backs and pressure from the pharm company on doctors they prefer to prescribe the suboxone, citing the addition of naloxone as the reason. This unfortunately keeps the people who require these drugs paying top dollar, when they would save thousands a year by getting a generic equivalent. The addition of naloxone makes it a different drug than the subutex meaning pharmacists can't substitute.

the pharmaceutical industry is a profit driven industry, and we are the ones who end up paying for it.

an example of a similar concept is ambien and intermezzo. Since ambien is an extremely popular drug and highly profitable as a result, instead of making a generic like everyone else the company decided to reformulate it into a subligual tablet. This means a new patent, and a reason for doctors to say "well I normally avoid prescribing the pills because they don't work as well, so I'll write you a script for the subligual tablets since I'm more comfortable prescribing a drug I've had success with in the past". Then you end up paying 2 or 3 times as much on a copay for your script, or an ungodly amount more if you don't have insurance
 
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I am right there with the Captain on 1-2mg's daily for maintenance I can dose at 6:00am before work and bang 3 packs of dope that night and get the full rush and nod that I always got from heroin
 
AjBoston said:
I had always thought that the naloxone was the antagonist that would cause the withdrawal?

What is the difference between bupe that contains naloxone and bupe that doesn't ?
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There is no difference. The naloxone isn't even active at such levels sublingully and even if it was, the bupe has a higher affinity rate than the naloxone, which is why during a bupe OD, it takes roughly 10x the usual naloxone dose to bring you back.
 
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