Bupe Suboxone/Buprenorphine FAQ & Megathread v2; 2010

[SubDude]

Yes, this is the wiki quote;Suboxone contains buprenorphine as well as the opioid antagonist naloxone to deter the abuse of tablets by intravenous injection. Controlled trials in human subjects suggest that buprenorphine and naloxone at a 4:1 ratio will produce unpleasant withdrawal symptoms if taken intravenously by patients who are addicted to opioids...
Basically, it states it stops people injecting the drug to get high. So, why all the USA people on here do that with Suboxone?

I would like to see the "research" and the methodology used. I suspect it was financed by RB to get the US market. For instance what dose of subs did they use for the IV and were the participants in a controlled envioronment or outpatients. If controlled... how long?

I wonder if they had a large number of addicts who IV 1mg suboxone and at the same time were hooked up to monitoring devices that measured changes in EKG, BP, EEG, Pulse...etc along with the responses from the addicts themselves. Then use the same controls for IV subutex.

Or did they just bring in volunteers off the street and IV them and ask how they felt?? There would be a lot of variables that could be manipulated to get the desired results. Based on the anecdotal repts here... it is a BS study and brings into question many other drug companies "research".

Generally speaking... I think the powers at the FDA [from a political standpoint] care much less about drugs for ORT than any other disease.

 

[subdetox]

So I called my doc and he said all he could prescribe for me is more suboxone. He said to take an 1/8th of a strip every other day for 10 days to help with my withdrawals. So my question is, is that just going to start my withdrawals over? I'm already almost a week through this, I don't want to start over in 10 days.

 

[subox0wned]

Catcalls, there is NO (None, Zero, Zip, Nada) difference between US Suboxone, & UK Subutex as far as effect goes, the naloxone is simply not active in any ROA, as the Bupe always out-competes it for a spot on your receptors (higher binding affinity). We get subutex too, it's not a UK exclusive, and the naloxone was only added to the formulation, more or less as a ploy to extend the product patent, and delay a generic from being manufactured. Lot's of uneducated medical "professionals" will try and tell you that the inclusion of naloxone does this or that, and prevents abuse somehow, but quite simply, it doesn't. Precip Withdrawls can be brought on by both meds, only if a user has a full agonist on their receptors when they take it, and this has everything to do with the buprenorphine, & nothing to do with the naloxone.

Edit:

So I called my doc and he said all he could prescribe for me is more suboxone. He said to take an 1/8th of a strip every other day for 10 days to help with my withdrawals. So my question is, is that just going to start my withdrawals over? I'm already almost a week through this, I don't want to start over in 10 days.

subdetox, to answer your question in short, yes if you get back on the sub, you will end up repeating the withdrawal again when you cease taking the sub, albeit perhaps with less intensity if you taper down properly. I don't understand what kind of doctor prescribes more suboxone for a bupe detox, but if you follow some of the suggestions I posted on the previous page, it may lessen the intensity of your symptoms

 

[Captain.Heroin]

Thanks for the edit, did not realise prices were taboo, since people seem to post how much their script costs, I thought I could post that info.

haha nah, that just means very few people read the rules, even people who have been here longer than I have.

Anyways, I think I got mixed up, in the USA, can you confirm or deny this, the Suboxone has a limit on how much bupe gets absorbed into the system to stop people from OD'ing on it? I read this on a Wiki one time and was always curious.

It said, too many people in the past had died from Subutex, they invented Suboxone, to stop that from happening.

Also, if that is the case, then, I can see why people complain about being on Suboxone, and want to get on Subutex in the States.

That's just a lie though. That's not actually true. It is very hard, if not impossible, to overdose on buprenorphine by itself. It's more common that people overdose with other CNS depressants with buprenorphine.

Naloxone in Suboxone doesn't prevent people from overdosing on buprenorphine and other CNS depressants.

Basically, it states it stops people injecting the drug to get high. So, why all the USA people on here do that with Suboxone?

That's like saying the war on drugs stops people from getting high. It doesn't!

So I called my doc and he said all he could prescribe for me is more suboxone. He said to take an 1/8th of a strip every other day for 10 days to help with my withdrawals. So my question is, is that just going to start my withdrawals over? I'm already almost a week through this, I don't want to start over in 10 days.

It depends on what you were taking.

If you can just tough it out from here on out, do that.

If you legitimately do not feel well, you could definitely try going back on it and going off again.

It would be smart to take 1/8th of a strip until you're half way through the strip, then to take 1/16th of a strip. This way you are gradually stepping off of it.

 

[SkagKush]

^ ya i would never just stop abruptly... im staying at 1mg for a long while, but i will taper down to .25mg when i plan to stop taking my suboxone all together...

id suggest taking Capt heroin's advice.....

 

[Been&Done]

Hmmm...Just called Reckitt in Canada, and Subutex is only by approval from Health Canada, and almost only approved individually or for Pregnancy cases (2 different peeps said that..what!?)
I Didn't feel the same with the Suboxone, when i did them sub-lingual and don't feel the need to switch now for some geographical/political reasons. A trip to the US would do it, but do i really have to cross the borders to get the meds i'v been on for a few months now and doing great? Hmmmm. Too freaking expensive to get if it's not pleasing you 100 %...it's the most i'v ever had to buy in one time, considering that the 30 pills of 8mg can last with me up to 6 months, let's say 5 to count the days when i'll feel like having a lil extra nod...so back to this long-term score, it's a lot of money and i want to have the choice to switch medications according to my needs, i'm paying the money after all, and with no insurance it seems like a joke. The nice lady at the pharma asked if i had insurance when i was picking up my last Subutex, and i said no so she froze and gave me a sad face (like sad for me) and said you know how much it is, so i replied with "yes, i do, but i have to do it" she smiled back and said u'r doing the right thing...My gf hugged me and eyes got watery...It was a good positive moment after 10 years of playing with fire and 3 failed attempts (the real latest ones) twice with Subutex and once with Suboxone. I would take a trip and clean up for 3 weeks, then BAM go back to the gear to feel the fresh effects and get really high! Probably i wasn't ready to really quit, and having the bupes made the "I'm quitting smack tomorrow" decision questionable...Even my doc said that the last time, and i'm quoting him: "I don't wanna give u any ideas, but a lot of people when having subutex, can take their H on weekends or so" I just smiled and i think it was all over my face that i actually DID THIS MANY TIMES! So basically this is my 1st time to be clean for 9 weeks in 10 long years, and i'm loving it and by clean i mean on 2 mg on subutex and less soon and a lot of greens smoking and wine with food. In a nutshell, Enjoying life and enjoying that i feel again and that my long lost soul came back to me. The positive attitude is also a great thing to have back, waking up with "it could be a good day today" in mind is very frequent and lovely.
I remember the days were only Tramadol was taken if u wanted to quit....You're not fucked...but NOTHING compares to Bupes..we should really be thankful that such drug is around now, and we're here discussing what to do with it, and what's the best way to take it...I mean be THANKFUL people, no1 needs to suffer. Waow...look at me rambling after morning dosing (maybe 1.5 mg) and thanks to BL and the wonderful people here, i started intra-nasal after 2 years of sub-lingual. I love it since i was an H sniffer, so lines always bring back something, and it's very psychological as i'm sure you all know, like the ones who IV, the needle, the spoon, the matches...well, i have the credit card and the bill and before when i was an H smoker, i'd have a lighter attached to a string around my neck the whole night so its handy...good times...waow..Rambling again!
If a trip to the US is not possible, then i think i'll take C.H words and try the Suboxone with an open mind and this time, i'll sniff my low doses..love it..compared to the sub-lingy.
I 'll leave you before i start again. Enjoy your Buprenorphine...Enjoy Life

 

[HdoubleODeezy]

^ i'm glad you find bupe as helpful as i (and others on here) do..
good luck on staying clean! i have been on it for 4 years and have been full agonist free basically the whole time, bupe is a great drug and has saved my life and put me back in control of it.

i snort my low doses also (IV once in a while when i get "needle fever" lol)
i truly enjoy bupe and what it has done for me. i just wish my son and daughters mother could straighten her life out as well for our kids sake .. ok done rambling now.

 

[SkagKush]

^ just a question ( no flame (just curious))

do you micron?

cotton once?

of filter with cotton several times?

 

[HdoubleODeezy]

^ just a question ( no flame (just curious))

do you micron?

cotton once?

of filter with cotton several times?

i use 45-50ml/cc sterile water,5ml/cc luer lock syringe, a .22 micron filter, a 50ml vial,and add .5ml benzyl alcohol to the solution after micron filtering the entire batch of however many tabs or strips i use for that particular solution. usually 1mg-ml/cc.

EDIT: i have been doing it that way ever since micron filters were ever mentioned here on BL. (well since they were mentioned for suboxone anyways.)
CH was my mentor lol.

 

[SkagKush]

ok cool.....i also think his technique for storage is pretty bright......

i would just prep a single shot (personally)...i cant be injecting all the time (girl)

 

[HdoubleODeezy]

^ don't get me wrong, i have done that a few times also when i don't feel like having a huge batch that will last me a month sitting around calling my name every few hours lol.. but if i was preparing a single shot i would much rather use the strips than the tabs, and would filter with cotton a few times and the solution would be completely clear.

 

[Been&Done]

Good job for the 4 years, I only hope to be there sometimes soon, only 3 years and 8 months to go
I feel your positivity when talking about Bupe "saving your life", and yes it did the same to me too. The journey back to life is an important one i truly believe, as there is no seeing the light if there's no dealing with the darkness, and i know i appreciate life even more now, and still to come. As for the mother of your children, i'm sure you know how it goes, she has to want to get clean herself, you can only say so much or direct her so much, the final decision is hers and hers alone, unless in cases of interventions and these are not my cup of tea or should i say cupS. If the problem is opiate-related, then definitely Buprenorphine is the magic key to wellness nowadays and is very much worth trying.

 

[*=Regulator=*]

Well as of today I'm two weeks clean of Suboxone, all other opiates and alcohol.

Not much but it's a bit of a milestone! I'm still battling with insomnia and some nausea but I'm well on the way to the lifestyle I've been working toward for the past few years.

 

[SkagKush]

to been and done..... BMT or MMT should be used as a secondary treatment after trying to taper, or go CT...... usually you can only go on a program after failing at sobriety several times.....

to regulator..... when i quit i never really stop drinking....im not even at the point of saying that alcohol should be a no no, when it clearly is....

 

[hydrochron]

Well as of today I'm two weeks clean of Suboxone, all other opiates and alcohol.

Not much but it's a bit of a milestone! I'm still battling with insomnia and some nausea but I'm well on the way to the lifestyle I've been working toward for the past few years.

Keep up the good work, it's good that your not drinking either. That's going to help you recover fast. And it also helps make things alot less complicated. In another week you should start feeling alot better, then you might have a few minor symtoms that linger for awhile. But they'll go away, especially if your staying healthy.

Keep up the good work and keep us posted.

 

[Captain.Heroin]

to been and done..... BMT or MMT should be used as a secondary treatment after trying to taper, or go CT...... usually you can only go on a program after failing at sobriety several times.....

to regulator..... when i quit i never really stop drinking....im not even at the point of saying that alcohol should be a no no, when it clearly is....

Good advice.

 

[*=Regulator=*]

Thanks guys.

I've mentioned it before (as have several others) but exercise has been the most powerful tool in getting over these withdrawals. I've been pushing myself pretty hard every day and the effect has been nothing short of miraculous.

I know it's hard but if you're in WD, please try and get some aerobic exercise, even if it's just a walk. It tires you out which helps you sleep, gets the endorphins flowing, kills time and makes you feel proud that you've achieved something.

The next step is a slow taper down from 20mg valium a day and then I'm completely drug free.

 

[Captain.Heroin]

Thanks guys.

I've mentioned it before (as have several others) but exercise has been the most powerful tool in getting over these withdrawals. I've been pushing myself pretty hard every day and the effect has been nothing short of miraculous.

I know it's hard but if you're in WD, please try and get some aerobic exercise, even if it's just a walk. It tires you out which helps you sleep, gets the endorphins flowing, kills time and makes you feel proud that you've achieved something.

The next step is a slow taper down from 20mg valium a day and then I'm completely drug free.

I definitely agree. Exercise is great.

I haven't ever had to taper off of benzos, but the sooner you get off the better.

 

[catcalls]

On daily pick-up. Saturday today, and the pharmacy is not open Sundays, so I get two 2mg pills to take home with me. Not tempted at all to take extra. Learned that lesson the last time I double dosed and nearly OD'ed.

It is surprising how much abuse the human body can take. And on this note I have a question;

Are there any long term Subutex use health concerns that I should be made aware of?

I ask because 2011 is 4 years on Subutex.

 

[jamesBrown]

On daily pick-up. Saturday today, and the pharmacy is not open Sundays, so I get two 2mg pills to take home with me. Not tempted at all to take extra. Learned that lesson the last time I double dosed and nearly OD'ed.

It is surprising how much abuse the human body can take. And on this note I have a question;

Are there any long term Subutex use health concerns that I should be made aware of?

I ask because 2011 is 4 years on Subutex.

I dont thinik they have much actually research or data on the long term effects of using subutex or suboxone for long periods of time, since its fairly new to the medical world as a maintanence drug. Before it was only prescribed for short amounts of time in the form of Temgesic or Buprenex(spelling).

I think the only thing we know about long term use of bupe is that it causes dependancy just like any other opiate(except a littel different) but thats not even guaranteed and is more based on your daily dose level and the amount of time you have been on them.