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OD Moderators: Keif’ Richards | negrogesic
Bupe Suboxone/Buprenorphine FAQ & Megathread v2; 2010
- Thread starter Captain.Heroin
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Captain.Heroin
Bluelight Crew
I'm glad to hear that man!
In other Suboxone news, I tried buprenorphine intramuscularly (IM) today. I'm pretty sure it worked very well, with a somewhat slower onset (though I could still feel it coming on).
It also seemed to "last longer" and not end so abruptly.
I think I won't IM often until I get to the exchange so I can at least have plenty of various gauges of insulin syringes.
Captain.Heroin
Bluelight Crew
I prepared it the same way I do my IV shots, micron filtered. I have a micron filtered solution ready to go at any time, so I just used it.
Same gauge though, a 31G, 5/16" tip works fine for IMing for me.
For a "one time deal" I would recommend the IV route. The IM route is good, but I wouldn't really advise it to anyone unless they were experienced with IM injection procedure, etc.
If you don't want to have to deal with track marks, an IM injection is a lot less noticeable (after IMing drugs, I will often lose sight of where I did the injection). If it bleeds then it's noticeable, but most of the time that won't happen.
Since I have only IM'd buprenorphine once thus far, I still want to do it a few more times to get a better feel for it. However I was pretty impressed with the ROA as a whole.
Jabberwocky
Frumious Bandersnatch
Does anyone know if its bad to be putting citric acid/lime flavor, or any of the other contents of the new Suboxone film strips in the rectum daily?
I came from Subutex, and am concerned about such damage. Also, if anyone knows anything about the safety of naloxone in the rectum.
I came from Subutex, and am concerned about such damage. Also, if anyone knows anything about the safety of naloxone in the rectum.
Captain.Heroin
Bluelight Crew
Jabberwocky
Frumious Bandersnatch
It weirds me out to smell the old Suboxone scent, knowing it has flavoring, with rectal administration. At least it doesn't have sugar.
Captain.Heroin
Bluelight Crew
*=Regulator=*
Bluelighter
Quick one: the Immodium on sale here in Aus comes in packs of 8, 2mg pills. To take a dose like Suboxone did above I'd literally need to eat two entire packs in one hit. Is this safe?
I'm going to go buy a couple of packs now but I don't want to kill myself by chowing through enough drugs to kill Elvis twice.
Thanks
I'm going to go buy a couple of packs now but I don't want to kill myself by chowing through enough drugs to kill Elvis twice.
Thanks
*=Regulator=*
Bluelighter
Thanks Skag.
Just got some generics @ $7 for a pack of 20. That compares to $16 for a pack of 8 for the Immodium brand name shit! Time to dose up - hope you're right!
Oh yeah - thanks for the kind words and encouragement SubDude
Mate, I wish I had your luck/metabolism/whatever. This last week has been the shittiest of my life. Maybe it's all about that 1/4mg part way through the process. Might be a good learning for others coming off Suboxone!
Just got some generics @ $7 for a pack of 20. That compares to $16 for a pack of 8 for the Immodium brand name shit! Time to dose up - hope you're right!
Oh yeah - thanks for the kind words and encouragement SubDude
Mate, I wish I had your luck/metabolism/whatever. This last week has been the shittiest of my life. Maybe it's all about that 1/4mg part way through the process. Might be a good learning for others coming off Suboxone!
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astroboy007
Bluelighter
So guys, i want to shoot my suboxone, any hints, tips or advice? Will i feel it, 16mgs?
JamtasticX
Bluelighter
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Shooting 16mgs is a ton of suboxone to shoot at once. Additionally, I doubt you will "feel it". 16mg is a really high dose, I would advice drastically cutting your dose before you attempt to get high off it
astroboy007
Bluelighter
OK, what about shooting 8mgs?
JamtasticX
Bluelighter
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Well here's the thing,
What dose do you usually take suboxone, and what route of administration. Shooting 8mg would be about the same as taking 24 under the tongue, in terms of bioavailability.
Captan heroin will disagree, but I wouldn't think there is a huge difference between shooting, or sniffing, whatever. The difference is in the bioavailablity, but either way bupe will still cross the BBB and essentially be the same.
I usually sniff 2-4mg a day, at most, of suboxone. Which would be about .75-1.3mg shoot up. Captain heroin is even lower with like .025mg per shot (that could be off, but he shoots crazy small amounts).
8 or 16mg shoot is a lot of bupe. So depending on how much, and what way, you usually take, you could work something out to how and when to shoot in the future, but it's impossible to say w/o knowing everything.
Bioavailability -
Sublingual ~30, Sniffing ~50, Shooting IV ~100
*=Regulator=*
Bluelighter
I'd be extremely careful shooting that much. A sublingual 24mg dose is massive, depending on tolerance. I took 24mg sublingual and I was otherwise taking 12mg every day. 24mg put me out the for the count (not in a 'take me to the ER way', more like a 'no way can I walk down these stairs without falling on my head way).
On other hand, if you're used to taking that much, maybe it would be safe. I'd wait until a couple of other people have confirmed it's not going to kill you before you do it (no offence Jam).
On other hand, if you're used to taking that much, maybe it would be safe. I'd wait until a couple of other people have confirmed it's not going to kill you before you do it (no offence Jam).
JamtasticX
Bluelighter
- Joined
- May 3, 2010
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- 916
Why would I take offence? I'm telling him not to shoot up that much.
In terms of bioavailability 8mg shoot up is equal to about 24mg under the tongue. Or the reverse 8mg under the tongue is equal to about 3mg shot up. I was simply explaining the bioavailability.
I don't think that it will kill him, but I don't think he should shoot up that much either. I think if you're trying to achieve a high you'd be much better off lowering the dose you take every day until you get to a level where smaller amounts can be taken w/o having to worry about tolerance or massive amounts
Cane2theLeft
Bluelight Crew
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- 12,673
Jam and Reg covered the safety and bioavailability issues and I just wanted to throw in another aspect.
Being a partial agonist, buprenorphine has a ceiling for the opioid agonist effects that is equivalent to about 30mg of methadone and for most people, this ceiling is reached around 2-4mg of buprenorphine. Doses above this level will still have effects but you won't get a stronger opioid high no matter how much you increase the dose. Beyond the level where you reach the opioid-effect ceiling, for the most part its just more side effects and longer periods of saturation of your receptors so full agonist won't work.
If you get certain effects from 8mg, its very unlikely you'll get a better high if you double or triple that amount and for many people, they get more pleasurable effects at lower doses.
Being a partial agonist, buprenorphine has a ceiling for the opioid agonist effects that is equivalent to about 30mg of methadone and for most people, this ceiling is reached around 2-4mg of buprenorphine. Doses above this level will still have effects but you won't get a stronger opioid high no matter how much you increase the dose. Beyond the level where you reach the opioid-effect ceiling, for the most part its just more side effects and longer periods of saturation of your receptors so full agonist won't work.
If you get certain effects from 8mg, its very unlikely you'll get a better high if you double or triple that amount and for many people, they get more pleasurable effects at lower doses.
*=Regulator=*
Bluelighter
@Jam: was just saying to astroboy007 to wait for a couple more responses before banging 24mg. Was saying 'no offence' because I didn't mean to imply your advice was incorrect or suggest that it wasn't useful.
On a slightly related note: I know that the naloxone in Sub has zero effect but is it possible that it might result in precipitated withdrawal if a massive dose like 24mg was shot? Or would the bupe still not 'allow' the naloxone to bind to the opioid receptors?
Back to me :D
I took about 40mg of Valium at 2pm today, then at about 7pm took another 40mg valium, 26mg lope, 10mg clonodine, 40mg Zolpidem (Ambien/Stilnox) and had about three alcoholic drinks. I still didn't get to sleep until about 9pm and have just woken up at about midnight. I don't fucking understand how I can take that many downers, find it difficult to fall asleep and then wake up 3 hours later! It's frustrating the shit out of me.
I took another 20mg Val and 20mg Zolpidem just then so hopefully can get some more sleep soon - I really can't take another night of sitting around until the sun comes up before getting another few hours of shit quality sleep. Any ideas on the insomnia? Do you think it's still part of the Sub WD or could I be on the wrong meds? I talked to my doc about switching to temazepam - would that be more effective than valium?
On a positive note, no nausea upon wakening and have a bit more of a clear head. The only change in my medication / behaviour was the big dose of lope last night so I'm hoping this means that the WDs have peaked and I might be able to start reading soon. I'm now 7 1/2 days off the Sub. Surely I'm over the worst of it now. I'm getting pretty depressed about how long it's lasted already so if I'm worse tomorrow, I might have to bite the bullet and get a 1/4mg of Sub. I just wish I could read to pass the time.
That's me - good luck everyone else!
On a slightly related note: I know that the naloxone in Sub has zero effect but is it possible that it might result in precipitated withdrawal if a massive dose like 24mg was shot? Or would the bupe still not 'allow' the naloxone to bind to the opioid receptors?
Back to me :D
I took about 40mg of Valium at 2pm today, then at about 7pm took another 40mg valium, 26mg lope, 10mg clonodine, 40mg Zolpidem (Ambien/Stilnox) and had about three alcoholic drinks. I still didn't get to sleep until about 9pm and have just woken up at about midnight. I don't fucking understand how I can take that many downers, find it difficult to fall asleep and then wake up 3 hours later! It's frustrating the shit out of me.
I took another 20mg Val and 20mg Zolpidem just then so hopefully can get some more sleep soon - I really can't take another night of sitting around until the sun comes up before getting another few hours of shit quality sleep. Any ideas on the insomnia? Do you think it's still part of the Sub WD or could I be on the wrong meds? I talked to my doc about switching to temazepam - would that be more effective than valium?
On a positive note, no nausea upon wakening and have a bit more of a clear head. The only change in my medication / behaviour was the big dose of lope last night so I'm hoping this means that the WDs have peaked and I might be able to start reading soon. I'm now 7 1/2 days off the Sub. Surely I'm over the worst of it now. I'm getting pretty depressed about how long it's lasted already so if I'm worse tomorrow, I might have to bite the bullet and get a 1/4mg of Sub. I just wish I could read to pass the time.
That's me - good luck everyone else!
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BanginMyLifeAway
Bluelighter
i had a strip from a friend and i cut it in 3 pieces i took one yesterday ....one today..but i tried to put it under my tongue it stuck there for a sec.. the kinda stuck to my teeth and i had problems gettin it disloved in the correct spot.. should i take my last piece or do yall think it will work... i gotta be at work in like 30 min
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