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Bupe Suboxone/Buprenorphine FAQ & Megathread v2; 2010

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I on average do 1-3 0.5 mg shots of suboxone a day. And at these dose levels, I get practically ZERO blocing effect from the bupe. I can do some heroin or oxy or whatever immediately after I dose some suboxone and I feel atleas 90% of its effects.

Even if I dose 4 mg's of suboxone I can still feel around 75-80% of a full agonists effects within an hour or two after dosing the suboxone.

So basically I can take a full agonist anytime I like, I just choose not to for the most part(once every couple months ill do 1 shot of heroin or soemthing).....but the option to get high is always there for me if I choose to. Its just the suboxone has allowed me to see that I dont need/want to live everyday doing dope so I dont.....I simply take tiny doses of sub every day and enjoy life.
 
jamesBrown said:
I on average do 1-3 0.5 mg shots of suboxone a day. And at these dose levels, I get practically ZERO blocing effect from the bupe. I can do some heroin or oxy or whatever immediately after I dose some suboxone and I feel atleas 90% of its effects.

Even if I dose 4 mg's of suboxone I can still feel around 75-80% of a full agonists effects within an hour or two after dosing the suboxone.

So basically I can take a full agonist anytime I like, I just choose not to for the most part(once every couple months ill do 1 shot of heroin or soemthing).....but the option to get high is always there for me if I choose to. Its just the suboxone has allowed me to see that I dont need/want to live everyday doing dope so I dont.....I simply take tiny doses of sub every day and enjoy life.
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Damnit, you're lucky. I just shot up 5 bags and 16mg of Dillaudid and I hardly feel anything. The last time I took bupe was over 30 hours and it was a .5mg shot. I should be nodding off by now. I took some lyrica, benadryl, promethazine, and I'm about to smoke some JWH-018 to see if I can get high off this shit. I used a lot of product for seemingly lucky.
 
Bupe said:
Damnit, you're lucky. I just shot up 5 bags and 16mg of Dillaudid and I hardly feel anything. The last time I took bupe was over 30 hours and it was a .5mg shot. I should be nodding off by now. I took some lyrica, benadryl, promethazine, and I'm about to smoke some JWH-018 to see if I can get high off this shit. I used a lot of product for seemingly lucky.
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Well, before that 0.5 mg shot, when was the last time you dosed suboxone, and how much where you doing on average, and how often?

Because, if you had been taking like 8-24mg's(or somewhere around that) for a long time because thats what you were prescribed, then you read on BL that less is better and then quickly lowered your doeses, and just recently started doing 0.5 mg shots, or maybe that was your first 0.5 mg shot(I dont know)....then there is a good chance that there is still ALOT of suboxone in your system built up that will take a while for it to clear out. If thats the situation, then I bet it would take atleast a couple weeks of you only doing 0.5 mg doses for you to be able to feel the effects of full agonists at any time like I do.

I have NEVER taken my full 12 mg prescribed suboxone dose.....I have ALWAYS only taken tiny doses.....the most ill ever take is 4 mg's but 90% of the time its 0.5-0.3mg's and i have been doing it like this for a long time....so I definitely dont have a shitload of bupe built up in my brain.
 
Just started Suboxone 2 weeks ago, everything is going great except I get some hot flashes and sweats. I was a heroin addict for 5 years str8 then cleaned up for 8 years totally clean off everything, then I had a infected colon and was given Ciprofloxacin and had a BAD REACTION and both my tendons in my ankles swelled up and could not walk for weeks and was in so much pain. I was given dilaudids and T'4's for the pain as I am a server by trade and need to be on my feet 8hrs. a day. I was on the dilaudids for about 7-8 months then weened off them. Pain started coming back again 2 months and started using Heroin again
first snorting then back to IV again. I knew it was becoming a problem again so tried the methadone but that was not enough so I am currently on 8mg Suboxone I am planing to taper off when I see my doctor this week. will I feel much difference going down 2 mg a week
or will I need some clonodine to help with WD's?????
 
I'm planning to use my remains of buprenorphine (that is 10mg buprenorphine freebase). I already know I won't go to zero with methadone this year (with semester starting here October 1, it's impossible as I'm now again at 10-5 and yet it makes me withdraw at night).

So if I do this, I will stop methadone and wait for w/d (it's fast for me, 20h at most for feeling terrible). By that time I will have prepared a salt of buprenorphine ready to inject. Considering 1) I have to take 20 - 20 methadone at least to feel alright, 2) I will have tolerance to opioids in general (minus that cross-tolerance between bupe and 'done can't be great as methadone vs. morphine has, as I know, the least cross-tolerance from known opioids, well 3,3-diphenylpropylamines generally, I guess), and finally 3) when used s.l. I used to need 16mg to feel I'm bright and it works somehow -

my question is to some acknowledged people in this area (I used bupe and 15,16-didehydrobupe only for maintenance for like 3 months IIRC s.l.): what dose should I inject at one time to feel anything? (please no 0.02mg answers, such a dose of 3-MF actually helped me once to break through bupe when I tried to use it for maintenance but it helped nothing so I got mad)

26MCGS of bupe? um that fazes me how people talk all that, what do you do, crush up a pill, and buy some MCG scale? or how an 8mg bupe pill lasts someone 1 month, hard time believing it...
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You don't have to have some scale in micrograms to do this. If you know, you've got 100 8mg pills, then you know you have 800mg. You dissolve it in 50ml of water (16mg of buprenorphine HCl should dissolve in 1ml of water, actually that's a ceiling so you might want to use other solvents like MEG), now having 50ml of a concentrated solution of 16mg per 1ml, you measure like 10ml and you know you have 160mg of bupe HCl in it (in theory of course). You want to actually have 160mg per 1 000 000ml to get a 0.016mg (i.e. 16mcg) per 1ml. I didn't think about numbers but that's just an example, it's straight math and you might use a measuring cylinder to add so much water (it won't be exact; actually only pipette from lab glass give you the most accurate volume but do you really need it for this process?)
 
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^^^ adder I would start at a miligram then go up in .5mg dosesevery 10 minutes until your out of withdrawl. Be aware bupe doesnt have a rush and the IV effects can take a few minutes to become pronounced for some reason. Also it really hurts to miss shots of bupe so be conservative and use good technique draw back half way through the shot you know the drill.
 
Yes, I know there's no rush from bupe. The only reason I want to i.v. it is bioavailability (s.l. administration is a waste of bupe, the peak is higher after i.v. and concentration in blood stays higher). It really may be success, total failure, or overdose as it's i.v. Anyway, I wouldn't want to inject several times. Working up is safer but I feel I just need to hit the spot. Thanks for reply.
 
ok everbody listen up :)

1 month/1 bundle a day fentanyl habit

ive got a 3wks 10bag/day intranasal fentanyl (powder form) habit. can 0.2 Temgesic's HELP at least SOME-WHAT???

i have 4 x 0.2 mg (total of 0.8mg TEMGESIC (European brand for suboxone, i think).

also have plenty of tramadol and benzos. nothing else i can think of. reommendations, please.

dont think loperamide is for me as im constipated enough as it is,
i dont want to shut down completely if you know what i mean
 
Suboxone Film Strips Picture and info

For those interested here is a picture of the new film strips.

http://i51.tinypic.com/2wrkytz.jpg

One other thing I would like to mention is something my doctor told me about them.

1) The strips come out gummy, not like a Listerine strip, so they will likely be hard to cut, but with very sharp scissors can be cut to 1/8 and 1/16 size and smaller also they are lemon-lime flavor.

2) That RB is replacing the tablet formulation with the strip formulation.

#2 is good and bad. Bad for those who like to snort or inject, but good news that a generic formulation of the tablets are imminent and RB is changing gears to keep making money.

EDIT:
Also the manufacturer will be offering a discount program for all film prescriptions that applies up to $75 toward the patients’ out of pocket cost of the prescription for the first few months. (Through March) Patients will go online and print out a discount card to bring to the pharmacy. (Prohibited by law in Massachusetts.)
 
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Are you saying that they are getting rid of the tablet suboxone and replacing it with these new strips? Cuz im pretty sure thats not true. My suboxone doctor showed me the new strips 2 days ago at my last appointment. A rep had come and given him sample packages....and he ALSO told him that there would be both the pill AND the new strips available. They are not getting rid of the pills because of how some people might react to the new strips, atleast thats one of the things my doctor said. He also explained it in alot more detail but I was really fucked up on benzos so I dont remember alot, but I specifically remember him saying that I didnt have to take the strips if I liked the pills better....because I expressed to him that I like the pills and didnt wanna switch anythign up. He told me not to worry, that BOTH were going to be marketed.
 
jamesBrown said:
Are you saying that they are getting rid of the tablet suboxone and replacing it with these new strips? Cuz im pretty sure thats not true. My suboxone doctor showed me the new strips 2 days ago at my last appointment. A rep had come and given him sample packages....and he ALSO told him that there would be both the pill AND the new strips available. They are not getting rid of the pills because of how some people might react to the new strips, atleast thats one of the things my doctor said. He also explained it in alot more detail but I was really fucked up on benzos so I dont remember alot, but I specifically remember him saying that I didnt have to take the strips if I liked the pills better....because I expressed to him that I like the pills and didnt wanna switch anythign up. He told me not to worry, that BOTH were going to be marketed.
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Ya my doctor told me the Rep. who came in and also gave him the sample in the picture told him they are going to phase out the pill due to many reasons but mainly because they believe they are not abusable like the pill and hinted that a generic of the pill is imminent. This is all I know about it.

The more I think about it the more it could well be true, doubly so if a generic pill hit markets as if one could not take the strip they would just Rx the generic tablet.
 
It MAY be true that the brand name suboxone tablet will be slowly phased out, but it would take a LONG time. That is also one of the things my doctor talked about, its kinds just coming back to me cuz of how fucked up I was on k pins.......I think my doc mentioned that it would take them around a year or so to phase it out, and thats the EARLIEST time frame, probably 2-3 years he said....but maybe he didnt know what he was talking about....but I believe him, hes been a very knowledgeable doctor to me.

Either way, I will have enough suboxone pills saved up to last me forever by the time they force me to go on the strips, since I only do 0.5 mg shots 1 pill lasts me weeks.

I would literally stop my suboxone treatment and just use my saved up pills if they tried to force me to take the strips.....I woudl have enough to SLOWLY taper down overe like a 2 year period on my own.

THANK GOD for the ability to get a nice high off of suboxone at such low doses!!
 
Does anyone know if it's possible to use opiates while on Bupe for pain? I know Bupe will block the majority of the opiate in an addicts maintenance dose, but would it be possible to redose with say .5mg (down from 4mg daily), and still feel the pain killing effects of the opiate?

I have chronic severe migraines, and Suboxone has worked awesome so far, when I DON'T have the migraines. It takes away all the cravings, makes me feel better overall, and feels like it helps my depression and anxiety a good bit as well.

But these Migraines are debilitating, this current Migraine I'm experiencing now has been with me since sunday night, and while Tramadol does very slightly take some of the edge off, it doesn't relieve pain like an old Hydrocodone or Oxycodone would.

I really wish I didn't have to even think about using an opiate again, but the opiates seem to be the only things that help (and I've seen neurologists, had MRI's done, been prescribed 12-14 different preventatives and abortives, none which work).

So I was thinking, while I've already taken my 4mg dose this morning, could I drop it to .5mg tommorow morning, and take a 10mg hydro for some pain relief if the migraine is still there?
 
An Intriguing Suboxone Mystery - Surprise Euphoria.

Ok. This is bizarre and I'm trying to figure out what could be the cause, maybe see if any of you have had similars.

I've been on Sub since May of 2008. My dosage has fluctuated between 16 and 32 mgs a day, because I not only use it for a very high tolerance addiction, but for chronic back pain. I'm actually in the process of weaning off of it at a SNAIL'S PACE, I mean, glacier like speed. I'm down to 12 mg.

SO. Last Friday was refill day and because I'm a crummy addict I talked myself into "deserving" an extra 8mgs. It was friday night, i was alone, I thought I could get some writing done.

Keep in mind I've been on this for TWO YEARS.

Suddenly, about an hour after taking the extra 8mg, i felt that kind of warm, heavy legs feeling, my face flushed and I was treated to my old pal Euphoria. I hadn't felt that for over two years (I really almost cried because I miss it so much)

Nothing in my life has changed, I've altered my dosages before, I've gone days without sub and back on before. I take effexor, welbutrin and concerta with my sub.

has anyone else experienced SUDDEN ONSET EUPHORIA, or discovered why sometimes it happens sometimes it doesn't? I remember someone in another thread remarking on the fact that they actually felt more and lower dosages. Could it also be the timing? that I break up my dosage during the day?

I'm just totally baffled.
 
I really dont know how to explain that. For one, you shouldnt be prescribed such high doses of buperenorphine for pain as well as addiction. Bupe only is used for pain at doses lower than 1mg. High doses of bupe allow for more of the antagonist effects to be felt, so all it really does is prevent withdrawal at those doses, not kill pain. You need to be under 1 mg for the analgesic properties of bupe to show because only at those doses can bupes metabolite norbupernorphine(which is a FULL AGONIST like heroin or oxy) attach to any receptors because it has a lower binding affinity than bupe does. So at high doses, all the bupe you took binds to ALL your opiod receptors, leaving none open for the norbupe, which is the chemical that actual kills the pain.

Thats why the drug "Tamgesic" which is buprenorphine in a pill form designed ONLY as a painkiller....only comes in doses of 0.2-0.4 mg's. And I know from experience that those low doses feel better, have more analgesic effects, and cause more euphoria, than any higher dose level. It's all because of the norbuprenorphine metabolite.

So my best guess as to how you got so "high" from taking another 8mg dose of bupe is that somehting else was going on.....like it might have been interacting with another medication you took, or maybe the actual location you took the medication in had changed, wich has been proven to cause varying levels of "highness" felt when taking your rgular medication/drug of choice. Or maybe you had missed a dose or two before that without realising it, so when you finally dosed again, it felt much better than usual. I know that when I take a day or two off from my suboxone doses, when i finally dose again, it feels much more euphoric than normal.

Other than that I have no clue as to why this happened to you. If I were you I would do my best to figure out what caused it and then repeat the process. Otherwise, just enjoy the fact that you got to get unexpectedly high one night for no apparent reason.
 
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Actually I recommend using the suboxone as your pain medication. Bupernorphine(suboxone) is prescribed under the name "Tamgesic" as a painkiller and nothing else....its not used for opiate dependancy. And "tamgesic" only comes in doses between 0.2-0.4mg's. That is because at low doses like that, it leaves some receptors in your brain open for bupes metabolite norbuprenorphine which is a FULL AGONIST(meaning it kills pain and gets you high). So if you simply lower your doses to like 0.2-0.7 mg's I think you will start to notice analgesic effects(painkilling).

When you take doses of suboxone that are higher than this(anything above ~2-4mg's), ALL your receptors are filled up with the buprenorphine, leaving no room for its metabolite norbupe to bind....because bupe has a higher binding affinity to your brains opiate receptors than norbupe does....thats why you need to take small doses so that then bupe fills up all the receptors it can, but since it was a small dose, you have many receptors left over for the norbupe to fill, killing your pain, and possibly getting you high...all because of the metabolite norbuprenorphine.

Also....I take doses of suboxone around the 0.5 mg range and I can take a full agonist like hydrocodone, oxycodone, heroin, etc....anytime I want without it blocking any of the effects.
But that only works because ive been taking this low dose of suboxone for a while.....you cant simply lower your high suboxone dose one day and then expect to be able to feel the effects of a full agonist....suboxone has such a long half life it would take atleast a few days for all that bupe thats built up in your brain to filter out. Also, whenever I choose to take a 2-4mg dose of suboxone, i can still feel atleast 80% of the effects of a full agonist within an hour or two afterwards. but remember....this is only possible because ive been regularly taking smaller doses and I would only take a higher dose like 4 mg's once in a long while. Therefore there is very little bupe built up in my system.
 
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