Bupe Suboxone/Buprenorphine FAQ & Megathread v2; 2010

[shanefrommaine]

I'm on 8-12mg of prescribed suboxone and I deal with serious pain on a daily basis

 

[jamesBrown]

I'm on 8-12mg of prescribed suboxone and I deal with serious pain on a daily basis

I dont get what your saying....

Suboxone at those dosage levels arent meant to kill pain, in fact suboxone isnt able to have practically ANY analgesic effects at those high doses.
You must be taking less than 1 mg of suboxone(maybe up to 2mg's MAYBE 4, but probably less) in order to get any pain killing properties from your suboxone.

Just like ive posted in many other posts many times......there is a drug prescribed for moderate to severe chronic pain as well as post-op pain called "Tamgesic" which is simply buprenorphine in tiny doses(0.2-0.4 mg's)....
at these doses it allows for bupes metabolite norbupe(which is a full agoinst like heroin, oxy, hydrocodone, etc....) to bind to your brains opiate receptors and kill your pain and get you high.

When you take high doses of suboxone(anythign over 2-4 mg's) it doesnt allow for the norbupe to bind and all you get is bupe binding to your receptors and since bupernorphine is only a partial opiod agonist, it doesnt really have any analgesic properties.....you MUST utilize the norbuprenorphine(full-agonist) in the small doses in order to kill pain with suboxone.

I would try lowering your dose to under 2 mg's a day....maybe even lower...in order to kill your pain that you say you have on a daily basis. I take 0.5 mg doses and it gives me a euphorical, painkilling high everytime. And I dont even have much pain to kill.....im on the suboxone for addiction....not chronic pain.

Feel free to ask any questions you may have. Im here to help

 

[jjdonkey]

I've had several people tell me that they think my dosage is too high. I don't know, I really trust my doctor, he's the head "addiction specialist" at two different recovery centers and he actually teaches the courses to other doctors for them to get their license to prescribe it. He was one of the first in the city to use Suboxone therapy. I had a huge huge habit, and debilitating pain. When I was in detox he gave me 2mgs every hour until I felt like I was NOT withdrawing. That got me to sixteen. After my back surgery he suggested I take 8 mgs three times a day (not all at once) to help with depression and low energy issues. Then I got into a little trouble with taking too much and I was honest with him that I was at 32 a day and running out early, so we tapered back down to 24 mgs, and we've been going down by 2 every three months or so.

it's so strange. I don't get why it happened, but I'll be sad if it never happens again!

 

[Georgie25]

For those interested here is a picture of the new film strips.

http://i51.tinypic.com/2wrkytz.jpg

One other thing I would like to mention is something my doctor told me about them.

1) The strips come out gummy, not like a Listerine strip, so they will likely be hard to cut, but with very sharp scissors can be cut to 1/8 and 1/16 size and smaller also they are lemon-lime flavor.

2) That RB is replacing the tablet formulation with the strip formulation.

#2 is good and bad. Bad for those who like to snort or inject, but good news that a generic formulation of the tablets are imminent and RB is changing gears to keep making money.

EDIT:
Also the manufacturer will be offering a discount program for all film prescriptions that applies up to $75 toward the patients’ out of pocket cost of the prescription for the first few months. (Through March) Patients will go online and print out a discount card to bring to the pharmacy. (Prohibited by law in Massachusetts.)

So they're immpossible to IV? How's the price difference between the film and the pills at the pharmacy?

 

[Captain.Heroin]

Taking a break from shooting up my subs for awhile. Dont have access to new rigs so I been re using the few I do have for way too many times and have horrible tracks on my arms and bruises, and I finally came to the realization that it just wasn't worth it anymore to not even feel a rush or high from shooting it to go thru much pain trying to find a vein to hit. I only really do it because it's quicker (until your veins are all fucked up then it can take me 1-2hours of stabbing at my arms, wiping blood off, repeat) to feel it than taking it sublingual. But hopefully giving it some rest will help some or maybe I wont feel the need to IV anymore once taking a break from it, whcih would be nice as well.

Good call man!

That really shouldn't apply for long term BMT, should it? After a few weeks/months/years on bupe only you would certainly be free of the physical addiction of your prior DOC.

?

That's essentially my experience with it. To get to a point where you aren't physically addicted, you need to taper, but it's fairly easy when you take your time with it, compared to tapering with full agonist opiates.

26MCGS of bupe? um that fazes me how people talk all that, what do you do, crush up a pill, and buy some MCG scale? or how an 8mg bupe pill lasts someone 1 month, hard time believing it...

http://www.bluelight.ru/vb/showthread.php?t=481622

At the moment, I use 26mcg per shot, anywhere from 4 to 8 times per day. 0.1 to 0.2 mg per day.

8mg, divided by 30 days, yields 0.26...mg.

Considering Buprenex is manufactured in 0.3mg/mL (equivalent of 0.324mg/mL buprenorphine hcl) vials, that's not impossible to do.

Water measuring is extremely effective.

I can add some anecdotal evidence to support StartedHydro. I just got off the phone with a friend who uses oxycodone infrequently. Absolutely opiate naive. His DOC is alcohol with pot/. I gave him some subs awhile back to pay off a debt. I asked him if he ever used the subs after using the oxys and his answer was yes. He's taken them both with and after oxy use and said he's had no sickness whatsoever. He couldn't recall amounts of each but this tends to backup hydros claim.

Anyway... neither side cited a specific source with quotations to back up their position... which leads me to believe the truth lies with the individual. Bupe is one drug which isn't good to make generalized statements unless there is absolute proof thru research one way or the other... and that isn't always reliable due to the propaganda influenced by govt. Most bupe dr's are inconsistant in what they tell their patients. One example is... they [and drug companies too] claim subs/naloxone will initiate WD's thru IV use which obviously isn't true for many users.... especially at low dose.

The only person at BL who I totally trust [opinion & knowledge] with regards to truth about drugs... is CaptainHeroin... perhaps he'll chime in for the final word.

I briefly went through the debate. Since I haven't personally experienced precipitated WD myself I don't have much subjective experience to share on this subject.

However, I think precipitated WD is more common when a large dose of buprenorphine is taken when opiates are still on your receptors. For non-addicted users, they tend to take smaller doses (of both full agonists and buprenorphine), and are less likely to send themselves into precipitated WD.

If you are an experienced IVing heroin user, and then going to 8mg to 32mg of buprenorphine, there is a much larger risk here, due to the fact that you have been going at a high potency opiate for a while.

The last times I used full agonists, I had been regularly using buprenorphine before hand, and within 4 to 6 hours I had started using buprenorphine again without any adverse effects. I had no opiate tolerance at this point.

I think that there is probably a correlation between the time you need to wait before taking Suboxone to avoid precipitated WD, and how up-regulated your mu-opioid receptors are from full agonist opiate tolerance.

This isn't to say that opiate-naive people can't have precipitated WD, I think it's just a lot less likely that they would do such a large amount of opiates, and then a large amount of buprenorphine shortly afterward. People who are addicted to opiates are more likely to have this happen to them, and hence are more likely to have precipitated WD's. I think that can safely explain why it seems that opiate-naive people don't have precipitated WD.

This is some good conversation though, I appreciate everyone's input about this. I don't want to say that I am definitively correct about this, As SubDude pointed out, like everyone else, I don't have any cited documents to prove my suspicion about this. A lot of other posts about this have had good insight. I am interested to hear what everyone has to think about this though.

howdy. ive been concentrating my efforts into the lyrica mega thread, but this is the other thread that applies to me as those are the two medications i take.

for anyone taking buprenorphine in any form, any ROA. pregabalin POTENTIATES THE SHIIIT out of it. its almost like shooting heroin again at times. ive cut down and it just feels so much better. i wake up, take 150mg of lyrica and a tiny shot of bupe (.3mg). about 1.5 hrs later i feel LOVLEY. so clear, so calm, yet with energy to conquer the day. it is amazing.

i HIGHLY suggest that anyone with anxiety issues check out lyrica, it way better than benzos. anyway, i just wanted to let you all know that i get a rush from shooting subs now that im on lyrica. its crazy, like when i first started taking it. very thankful, to say the least. peace.

Most doctors I have talked to would rather prescribe me benzos than gabapentin/pregabalin... maybe they don't know what these drugs are?

ok everbody listen up

1 month/1 bundle a day fentanyl habit

ive got a 3wks 10bag/day intranasal fentanyl (powder form) habit. can 0.2 Temgesic's HELP at least SOME-WHAT???

i have 4 x 0.2 mg (total of 0.8mg TEMGESIC (European brand for suboxone, i think).

also have plenty of tramadol and benzos. nothing else i can think of. reommendations, please.

dont think loperamide is for me as im constipated enough as it is,
i dont want to shut down completely if you know what i mean

Fentanyl is 2x as potent as buprenorphine... and 0.2mg isn't much for an opiate tolerant person, but yeah it will help at least somewhat. At least it should, keep in mind I haven't used fentanyl before. If you are going to do this let us know how well it works for you, and good luck!

 

[Captain.Heroin]

2) That RB is replacing the tablet formulation with the strip formulation.

#2 is good and bad. Bad for those who like to snort or inject, but good news that a generic formulation of the tablets are imminent and RB is changing gears to keep making money.

I guess it is good news for generic tablets. That's fucking retarded that they're going to replace the tablets with the strip.

Are you saying that they are getting rid of the tablet suboxone and replacing it with these new strips? Cuz im pretty sure thats not true. My suboxone doctor showed me the new strips 2 days ago at my last appointment. A rep had come and given him sample packages....and he ALSO told him that there would be both the pill AND the new strips available. They are not getting rid of the pills because of how some people might react to the new strips, atleast thats one of the things my doctor said. He also explained it in alot more detail but I was really fucked up on benzos so I dont remember alot, but I specifically remember him saying that I didnt have to take the strips if I liked the pills better....because I expressed to him that I like the pills and didnt wanna switch anythign up. He told me not to worry, that BOTH were going to be marketed.

Yeah, I somehow doubt that R&B will discontinue making Suboxone... if that is so, that is a horrible mistake on their part.

Does anyone know if it's possible to use opiates while on Bupe for pain? I know Bupe will block the majority of the opiate in an addicts maintenance dose, but would it be possible to redose with say .5mg (down from 4mg daily), and still feel the pain killing effects of the opiate?

I believe this is answered in the FAQ, but yes it is possible, but tricky. It is easy to go from buprenorphine to full agonists for added relief, but once you have taken full agonists, you should wait before taking buprenorphine again to avoid precipitated WD.

So they're immpossible to IV?

I don't believe that this has been determined, no one has shared the inactive ingredients with me yet.

 

[Captain.Heroin]

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What: Suboxone = buprenorphine/naloxone. Bupe is a partial agonist(mu) and antagonist(kappa). Bupe has higher mu affinity that most opiates, including some antagonists(naloxone, naltrexone). Its higher affinity allows you to shoot suboxone tablets. It also may cause precipitated withdrawals if you are dependant on other opiates. Also, its higher affinity blocks the affects of other opiates when taken in conjunction with bupe.

Dose: Depends on tolerance. 1-2mgs is a typical recreational dose for someone with no tolerance. If you're using bupe to taper off of another opiate, you should dose once you're experiencing wd's(typically 36-48 hrs. for most opiates). Start with 2-4mgs and dose at 2mg increments every 30-45minutes until a dose holds you. Most people take their full dose once a day.

Withdrawal: Typical physical and psychological symptoms associated with opiate withdrawal. Insomnia, chills, diarrhea, depression, anxiety, lacrimation, sweating, increased heart rate, etc. They are not as strong as a full agonist's symptoms, but may last longer. Physical symptoms last 1-2 weeks on average and psychological symptoms may last months.

As most opiates, it's recommended to taper down to the lowest dose possible before stopping. <1mg is ideal. The best way to dose at that level is to crush up a tablet and divide the powder into lower doses.

Ceiling: 24-32mgs

Bioavailability:

Buprenorphine bioavailabilities:

intraduodenal: 9.7%

intrahepatoportal: 49%

intramuscular: 68%
"The observed mean intramuscular bioavailability was 68%"
"Studies of buprenorphine bioavailability have also examined the intramuscular (bioavailability, 50%–100%)"

intranasal: 50%
"Studies of buprenorphine bioavailability have also examined the [...] intranasal (bioavailability, 48%)
"The bioavailability of buprenorphine, HCl (BPP) in sheep after nasal administration of two formulations has been studied. 0.9 mg BPP in 150 microl was administered nasally and compared to 0.6 mg i.v. The test solutions were formulated with 30% polyethylene glycol 300 (PEG 300) and 5% dextrose, respectively. The bioavailability for PEG 300 was 70% (S.D.+/-27%, n=6), whereas the bioavailability for 5% dextrose was 89% (S.D.+/-23%, n=6)."
"Mean intranasal bioavailability was 48.2 +/- 8.35% (mean +/- s.e.m.) of the intravenous value"

intrarectal: 54%
"bioavailability of the drug was found to be: [... ]intrarectal (54%)..."
"Relative to the 100% bioavailability from the intraarterial route the mean bioavailabilities were [...] intrarectal, 54%..."

intravenous: 98%-100%

oral: 10%
"the oral bioavailability for buprenorphine is state to be 10%"
"due to extensive first-pass metabolism, buprenorphine has very poor oral bioavailability (10% of the intravenous route) if swallowed"

sublingual: ~30%
"Buprenorphine is well absorbed sublingually, with 60% to 70% of the bioavailability of intravenous doses"
"Study results indicate that bioavailability of sublingual buprenorphine is approximately 30%"
"Literature on bioavailability of sublingual buprenorphine presents variable numbers ranging from. 19–58% of the administered dose."
"Relative to the 100% bioavailability from the intraarterial route the mean bioavailabilities were [...] sublingual, 13%"

transdermal: 15%

Other Notes:

• Bupe is CIII in the US.
• Metabolized by CYP3A4(see potentiation thread for potentiators).
• Half-life: 37 hours.
• Drug tests: Not detected by regular 5 panel tests.
• A interesting thread by 'medicine cabinet' about a new version of Suboxone that's currently being tested can be found here.
• Buprenorphine gets metabolized into norbuprenorphine and into conjugated buprenorphine and norbuprenorphine.
• Severe opiate withdrawal in a heroin user precipitated by a massive buprenorphine dose
• Clinical Guidelines for the Use of Buprenorphine in the Treatment of Opioid Addiction. -courtesy of thugpassion

Images:

Subutex

Suboxone

Generic Subutex

Suboxone Film Strips

Temgesic, 0.2mg

Buprenex Ampules

Locate a doctor that prescribes Suboxone.

Suboxone Assistance Program - Free Suboxone for Low Income Patients

 

[Captain.Heroin]

Frequently Asked Questions

Q: How long after my last bupe dose can I take an opiate and feel its effects?
A: It depends on what dose of bupe you were taking and how long. The short answer is 36-48 hours, though it may certainly be less, or more than that. Caution should be used when dosing, as you will still have a tolerance but it will not be as high as it was when you first got on bupe.

Q: I'm thinking about switching from methadone to bupe. At what methadone dose should I be when I switch?
A: Most places recommend being at 30-40mgs of methadone when switching. That may be hard to achieve since that level is lower than the recommended therapeutic maintenance level. Also, you'd have to wait at the very least 36-48 hours before your last methadone dose to switch in order to avoid precipitated withdrawal.

Q: Is bupe good for depression/anxiety?
A: Yes, it may help with depression and anxiety. It is not currently prescribed for either and its effectiveness has not been studied for long term use for either. You may be able to get it prescribed off label for depression/anxiety, but its not likely to happen. Here is an article on PubMed about a study on bupe being used to treat depression.

Q: Is bupe recreational?
A: Yes. Although it is rarely the preferred opiate for people who have experience with full agonists, a few people do prefer it to full agonists (i.e. morphine).

Q: Can you overdose on buprenorphine?
A: Yes you can, but typically not by itself. Buprenorphine causes respiratory depression which may lead to death, but typically wouldn't do so in a healthy individual, unless you combined other CNS depressants with buprenorphine, like benzodiazepines, alcohol, barbiturates, and other downers. The person most likely to OD on bupe has a low(if any) tolerance to opiates and may have taken another depressant. A buprenorphine overdose may not be reversed by naloxone(or naltrexone for that matter) due to bupe's higher affinity. Diprenorphine may reverse the overdose, but it is not regularly stocked by emergency personnel or hospitals. If a proper antagonist isn't available, the person suffering an overdose may be maintained with assisted respiration.

Q: Can I still get high on other opiates if I'm on bupe?
A: This depends on what dose of bupe you're on. You will most likely be able to shoot through a low dose of bupe (1-2mgs). Though some might be able to expect the full effects of the opiate you're shooting through with, it is often only partially felt for many people. Even at higher doses, if you take enough of the opiate you may feel it. This is not recommended, as you may overdose before reaching the desired recreational effects. It is better to wait until bupe is no longer effecting you, or to stick the course with bupe treatment.

Q: How come you can IV Suboxone? Isn't naloxone going to put you into withdrawal?
A: No, naloxone will not put you into withdrawal. If you are using heroin or a full agonist, and then use Suboxone, you will go into precipitated withdrawal if you don't wait for regular withdrawal first. If you are otherwise already on buprenorphine, IVing Suboxone will not put you into withdrawal. This is because buprenorphine has greater receptor affinity than naloxone does. There is no functional reason why naloxone is in Suboxone, and for all intensive purposes, Suboxone and Subutex are the same thing - both can be used with any route of administration.

Q: Is Suboxone safe to IV?
A: In essence, you should not shoot Suboxone. Unless you have enough patience and money to afford and use micron filters, Suboxone or Subutex, like any other pill, has risks when IVing. Missing a shot of Suboxone or Subutex may be more detrimental to your health, when compared to shooting out of a sterile ampule, or pure drugs in sterile water. Please read up on injection complications regarding pill based drugs, like Subutex, in the Case Studies thread. It is better, if you are truly intending on IVing buprenorphine (outside of the ampule version Buprenex), to read up on my Micron Filtering Mega Thread and FAQ and then purchase the necessary supplies to help enable a safer shooting experience for yourself.

Q: How good is bupe as an analgesic? What are the pain-killing properties like in comparison to other opiates?
A: This may vary from individual to individual, but what I can say for the average person, you will probably find that it is about half as good feasibly speaking as an analgesic (pain-killing) medication, compared to an equipotent dose of heroin, morphine, oxycodone, and so on. I have talked to several people who are pain patients, and they have a general consensus that while full agonist opiates are much better in the pain killing department, buprenorphine does help considerably when taking off the edge in mild to somewhat moderate pain cases. For people with moderate to heavy or severe pain issues, buprenorphine can do but only so much.

Q: If I am a pain patient, can I utilize buprenorphine?
A: Yes, it is possible. It will be most likely you will combine a compatible drug, like tramadol with it. However if you are going to combine full agonist opiates like morphine, hydrocodone, oxycodone, heroin, and so on, you are probably going to want to take a dose of buprenorphine first, and then once the effects are going, you can use other full agonist opiates on top of buprenorphine. However, you can't take another dose of buprenorphine until the full agonists have left your system. This is why if you're already dependent on full agonist opiates, it's better not to use buprenorphine as well (as you may go into precipitated withdrawal). If you have mild to moderate pain at best, and it flares up sometimes but doesn't at others, then you may be able to combine both buprenorphine and a full agonist on the days you need to, and then on the days you don't, you can stick to strictly buprenorphine.

 

[Captain.Heroin]

Suboxone Mega Thread Directory - Other links about buprenorphine in Other Drugs

Alcohol and Suboxone - Alcoholic Solutions for Higher BA With Sublingual Use**
Buprenex - should I IM or IV?
Buprenorphine and Antihistamine IV FAQ
Buprenorphine as a recreational drug?
Buprenorphine dosages commonly prescribed are unnecessarily high
Buprenorphine for depression?
Buprenorphine patches
Buprenorphine withdrawals?
Ketoconazole Potenation of Suboxone
Mephedrone and Buprenorphine
Micron Filtering Mega Thread and FAQ - How to Micron Filter Suboxone
Nasal Administration of Suboxone - Issues
Rectal (Plugging) Buprenorphine
Suboxone in place of Naloxone in the event of an opiate overdose*
Suboxone sublingual film official thread
Subutex has gone generic
Tramadol and Suboxone

Discussion in the Suboxone mega thread goes along quite quickly, so we have a few other threads to promote intermediate/advanced discussion of buprenorphine and its formulations. These threads are meant to divert some of the more advanced discussion that otherwise becomes buried in the mega thread.

If there's another link you think which would go well in this list of related buprenorphine threads, please let me know. We're trying to reserve extra threads on buprenorphine for more intermediary/advanced discussion mostly to reserve the mega thread for a place for questions that can be answered quickly, and the other threads for a place for questions which will otherwise not get the same discussion going on in the mega thread, due to its quick pace.

If you have an idea for a new thread on buprenorphine, it's probably best to figure out by talking to a moderator first to see if it's thread worthy or should be discussed in the mega thread.

*Not Advised. Opiate antagonists are the only safe thing to do in case of an opiate overdose. Please do not give people Suboxone if they have overdosed.
**also known as "6/7's method" or "SixPartSeven's method"

 

[Captain.Heroin]

Welcome to 9.0! | What's New?

As you acquaint yourself with the new Suboxone Mega Thread, you might notice minute changes we've made in this version, so I'll make some notes so you don't have to go through the whole thing all over again.

Images: I found images for generic subutex (thank you for posting the picture funkee), temgesic, buprenex, and sublingual Suboxone film strip (thank you to cballhp for posting that picture).

If there's any other additions, we'll make sure to post a note of it here for you.

 

[adder]

I don't think that those are coming soon here. And judging only by the fact that Suboxone has been available here since the beginning of 2008, I guess (but not Subutex, it's still not here). Interest among addicts that enter the program is little, e.g. if you wander around the point of maintenance program for some time, you'll find some junkie that will sell you methadone but your chances you'll get some Suboxone are scarce. Anyway, I don't know why it doesn't mean more places on "Suboxone program".

I decided to have those 10mg of buprenorphine freebase divide into 5 2mg solutions and if 2mg won't work, the next 2mg will follow. I'm kind of not convinced if I should do this at all. If it turns out that bupe doesn't even work for W/D, I'll be in trouble then. Last time it was short-lasting morphine I switched from to buprenorphine so it was easy and I didn't have much choice. Now that I have enough methadone (but it would be good to have doses from 5 days kept), maybe I shouldn't play with actually giving nothing bupe. I mean, I don't take methadone to get high, actually I could as I'm prescribed clonazepam for free and methadone + clonazepam is the closest combo to heroin for maintenance programs junkies (they drink their dose and take clonazepam with no tolerance and it really brings some kind of euphoria beside sedation). Anyway, I liked that smooth and kind of speedy action of buprenorphine, it made me feel like doing things at university without sedation, nodding or even euphoria, it was more like well-being, that's all. Almost everything I had, I gave to my ex-girlfriend long time ago when she needed it for w/d. Now I've got those 10mg and I look at it with some strange nostalgia.8)

 

[homeydontplaythat]

i think it should be part of bupe induction to take a benzo before starting. this would eliminate precip wd; take a bz for like 48hrs so you are well into wd without suffering too much and then start bupe. no way this will happen though since they are scared of possible interaction between the two. pretty dumb though. just because some junkie in france shoots temazepam with bupe and dies does not mean taking a benzo orally and bupe sublingually will do the same. hell, use ketamine if they are worried about cns depressants and bupe depressing respiration.

 

[adder]

I've been on benzodiazepines day by day for like 7 years and currently I'm prescribed 6mg of clonazepam a day. So benzodiazepines don't really turn me on...

 

[SubDude]

I guess it is good news for generic tablets. That's fucking retarded that they're going to replace the tablets with the strip.
Yeah, I somehow doubt that R&B will discontinue making Suboxone... if that is so, that is a horrible mistake on their part.

Hmmm... If R&B stops making the tabs and most of what is available is strips... I wonder if that could eventually affect the street price of subs tabs?? There are a lot of us with stockpiles and enough to last yrs & yrs. But then... I suppose we'll have to wait and see how the strips and generics play out for IV use. What ever happens, it gives me security knowing I'm not totally dependent on some dr or pharm company.

 

[cballhp]

So they're immpossible to IV? How's the price difference between the film and the pills at the pharmacy?

They are going to be priced the same as the tabs.

I am not 100% sure about IV, but from the looks of it and the makeup of the strips I doubt it.

 

[cballhp]

Hmmm... If R&B stops making the tabs and most of what is available is strips... I wonder if that could eventually affect the street price of subs tabs?? There are a lot of us with stockpiles and enough to last yrs & yrs. But then... I suppose we'll have to wait and see how the strips and generics play out for IV use. What ever happens, it gives me security knowing I'm not totally dependent on some dr or pharm company.

It would no doubt make the tabs worth much more as they are as of now saying the strips cannot be iv'd and sure as hell cant be snorted so those who like doing them that way will have to pay more...simple supply and demand.

 

[jamesBrown]

Dammnit....I should have taken the empty pouch my doc had showed me that was for the new strips....it might have had a list of the inactives on it. He literally put it in my hand to look at.

 

[askaboutme]

i have a Q for you guys. i have been shooting my generic subutex for about a month now. usually do 1-2 mg's per day. i start to feel minor withdrawals if i go more than 8 hours without.

yesterday i had some suboxone instead and because of my needle fixation, i shot that too.
the issue is i did about the same amount and got a weird rush where i felt cold almost like percip.w/d feeling. i continued to yawn often and just not feel like i should. tried it again today and it again did not feel like when i shot the tex. i thought the naxalone isnt active no matter what ROA you use??

 

[CLOUDnine420]

I did hear of this type of sublingual listerene thing for some opiod users who volunteered to take it. they said it didnt dissolve any faster and that it was about the same as a regular pill. god i hope my doctor dosent hear about this she might wanna prescribe it to me



dude for me tramadol with suboxone was as about as good as it gets for me getting euphoria and anasgelisia. was fucken awsome. when i took them together It was really a pleasant time the only downer was when the effects went away from the tramadol. is tramadol OTC? i doubt it I remember a couple years ago it wasnt on any legal status but i bet thats long gone.


I still dont understand why people say suboxone dosent make them euphoric or happy like other opiates. hell before suboxone I took tramadol a few times and got no effects. but my first 8 mg suboxone was better than heroin,codeine,vicodin,oxycodone. the euphoria and analgesia was alot stronger and longer lasting than all those other opiates listed. hell and i dont think I was opiate niave etheir since i was using everyday 6-10 10mg vicodin pills perday but who knows . just dont tell doctors that I said that. or theyll stop prescribing it to people because it theyll think it makes people feel good

A long time ago, when i was opiate naive i would do 1-2 mg of sub. and I always liked the effects. I thought there was good euphoria and nodding like crazy, however only one of my friends who tried it with me liked it.

 

[Captain.Heroin]

i have a Q for you guys. i have been shooting my generic subutex for about a month now. usually do 1-2 mg's per day. i start to feel minor withdrawals if i go more than 8 hours without.

yesterday i had some suboxone instead and because of my needle fixation, i shot that too.
the issue is i did about the same amount and got a weird rush where i felt cold almost like percip.w/d feeling. i continued to yawn often and just not feel like i should. tried it again today and it again did not feel like when i shot the tex. i thought the naxalone isnt active no matter what ROA you use??

I yawn all the time (and this happened to me with buprenorphine by itself, and with naloxone). I would say that this is a normal side effect. Precipitated WD should be extremely unleasant and not just mildly uncomfortable.