Yohimbe is hit or miss. You can get sick, and you can have a nice, shivery, speedy, sexy buzz with a partner. Pot is a requirement for a good time.
I read in one of the "Mary Jane Superweed" pamphlets years ago that it was important to only take Yohimbe if you were feeling 100% healthy and robust. Having a hangover or just feeling/being run down or unhealthy is a recipe for an unpleasant experience.
It also mentioned that mixing it with any stimulants at all was a big no no.
I kinda agree with you, in terms of a general tip for harm reduction purposes...
nevertheless... in my case yohimbe (bark, low dose in tea or tnw method) has helped even in the most contraintuitive moments:
like first days of kratom withdrawal: it's like it removes the kratom withdrawal anxiety and it exchanges it with it's own type of anxiety, but with euphoria and a lot of energy...
I have mixed with NEP, which is one of the most nor-epinephrine based DNRIs available... and it was a crazy time, the rush was so crazy and intense, it was almost overwhelming but when mixed with a benzo (after the first 20 minutes) was quite enjoyable, makes the orgasms and erection much easier and amazing.
So, generally, I think you're right, most people shouldn't try to use it when feeling unhealthy or fucked up with some physical problems, let alone mixing with stims..
but for some people it just works, seems that the bio-availability it's all over the place, very different from on person to another,
so it makes sense why some jacked gym-built giants cannot even tolerate 2.5mg of yohimbine, while some "weaker" people can tolerate up to 15-20mg... seems a very subjective substance. I personally love it when used in moderation, I have the feeling that it can precipitate adrenal fatigue quite fast.