Serotonin effected after amphetamine binges?

[DiRtYjErZ]

So I was originally under the impression that amphetamine's Action on the body was caused by it's effects on dopamine (& norepinephrine) and that the negative effects after binging (and reasons behind postloading) was because of depletion of dopamine in the body as opposed to MDMA which has a greater effect on serotonin afterwards. But recently after a binge last week I read that it may effect seretonin as well? I'm confused as to whether or not it has a significant effect on serotonin as well (specifically after an adderall binge). Any light that can be shed on this is greatly appreciated

 

[Nexius]

Amphetamine does affect serotonin in higher doses

 

[iameatingjam]

d-amps effect on serotonin is very little. Meth has a much greater effect on it.

 

[fryingsquirrel]

You can tell, too. Even at very high doses amphetamine is clearly missing something when you're used to meth.

 

[StaySedated]

d-amp has little effect on serotonin. i don't think it releases it at all, unlike meth which is a mild serotonin releasing agent. both have strong dopamine and norepherine effects, which makes up most of their mechanism of action.

 

[DiRtYjErZ]

That's what I thought. I knew amp was supposed 2 have no effect at all and that meth does mildly. Thx guys!