If you want a challenge and a steep learning curve, check out Elden Ring. It's nothing like anything you mentioned but I just started playing it yesterday and I haven't liked a FromSoftware game so much since Bloodborne, and I fucking loved Bloodborne.
FPS? Quake was recently remastered, and that'd probably be right up your alley. I also really enjoyed the Mass Effect and Halo series, but can't really stand the realistic warfare games like Call of Duty and Battlefield.
Fallout 4, Skyrim, and GTA 5 are all classics to have in reserve for when you're just bored and don't know what to play next.
This next one's kind of weird but if you have any interest in historical piracy and naval battles at all then give Assassin's Creed: Black Flag a try.
X-Com 2 was fucking phenomenal with tons of replay value.
As far as 4-X games go, there's always the latest version of Civilization to waste a few weeks on, but my personal favorite in recent memory is Stellaris-- a sci-fi empire builder in space.
Lastly, there are a few honorable mentions that I always like to put out there in these kinds of conversations: the Crusader Kings series, Mount & Blade: Warband and Mount & Blade: Bannerlord, and my favorite of all time: Rimworld.