I personally think that if you did a relatively small amount of salvia -- so not enough of a trip to totally blow you out of your mind -- it would be fine. Now, I'm by no means an expert on salvia, but when I've done small amounts, I get a nice, fuzzy feeling and beautiful, soothing visuals -- and I think this would combine well with e. I think that it would be worth a try -- just don't overdo it! If you like the combination at a low dose of salvia, you can always do more...