• N&PD Moderators: Skorpio | someguyontheinternet

๐ŸŒŸ๐ŸŒŸ Social ๐ŸŒŸ๐ŸŒŸ Rectify's molecular poetry thread

"I Know You Are Going To Dig This."

1-(1-azacyclohex-3-ene-1-yl)-(3-methoxyphenyl)cyclohexane.png


DEE_LITE aka DADDY'S_BOY
1-(1-azacyclohex-3-ene-1-yl)-(3-methoxyphenyl)cyclohexane

"Groove Is In The Heart!"

Just Add Endogenous Aromatase!!
 
1-phenyl-1-oxo-(4-morpholinyl)pentane.png


LULA_MCNEILL_LEHRER
1-phenyl-1-oxo-(4-morpholinyl)pentane

Honestly, I Would Love To Try This Molecule, But I Am Fresh Out Of Inhalers.

I Am Going To Go Ahead And Have To Give This One 4 Or 5 ***** Out Of 5.
 
N,N-diethyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane.png


ELIZA aka
BEOWULF/THE_CANTERBURY_TALES
N,N-diethyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane

MD-Ethylone Then The Clemmenson Reduction.
The Wolff-Kishner Reduction Is Probably A Completely Good Alternate Route.
 
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I am getting some pramipexole soon. I saw this patent you might be interested in:

Only know one person who was briefly prescribed that stuff.

It's an absolutely classic example of the 'indication creep' I have mentioned several times.

When dealing with Parkinson's disease, a 'less than optimal' side-effect profile is acceptable since, after all, the outcomes for people with that illness are the same - it's not quite but almost palliative (given UK law specifies palliative as life-expectancy of <6 months and with Parkinsons, that may or may not be the case.

But some marketing manager somehow got it licenced to treat RLS. At least in the UK the indication is 'severe RLS' as a nod to those side-effects.

Common or very common​

Appetite abnormal; behaviour abnormal; confusion; constipation; dizziness; drowsiness; fatigue; hallucination; headache; hypotension; movement disorders; nausea; peripheral oedema; psychiatric disorders; sleep disorders; vision disorders; vomiting; weight changes

Uncommon​

Anxiety; binge eating; delirium; delusions; dyspnoea; heart failure; hiccups; mania; memory loss; pathological gambling; pneumonia; sexual dysfunction; SIADH; skin reactions; sudden onset of sleep (can occur without warning); syncope

Frequency not known​

Depression; dopamine agonist withdrawal syndrome; generalised pain; sweating

Sounds great!
 
1-(4-oxo-cyclohex-2-ene-1-yl)-2-ethylaminopropane.png


SUSIE_Q
1-(4-oxo-cyclohex-2-ene-1-yl)-2-ethylaminopropane

Mind Your Push & Q's!
P --> Q
~Q --> ~P
P --> P
Q --> Q

The Last 2 Are Prima Facie.
 
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