N&PD Moderators: Skorpio
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4DQSAR
Bluelighter
Only know one person who was briefly prescribed that stuff.
It's an absolutely classic example of the 'indication creep' I have mentioned several times.
When dealing with Parkinson's disease, a 'less than optimal' side-effect profile is acceptable since, after all, the outcomes for people with that illness are the same - it's not quite but almost palliative (given UK law specifies palliative as life-expectancy of <6 months and with Parkinsons, that may or may not be the case.
But some marketing manager somehow got it licenced to treat RLS. At least in the UK the indication is 'severe RLS' as a nod to those side-effects.
Common or very common
Appetite abnormal; behaviour abnormal; confusion; constipation; dizziness; drowsiness; fatigue; hallucination; headache; hypotension; movement disorders; nausea; peripheral oedema; psychiatric disorders; sleep disorders; vision disorders; vomiting; weight changes
Uncommon
Anxiety; binge eating; delirium; delusions; dyspnoea; heart failure; hiccups; mania; memory loss; pathological gambling; pneumonia; sexual dysfunction; SIADH; skin reactions; sudden onset of sleep (can occur without warning); syncope
Frequency not known
Depression; dopamine agonist withdrawal syndrome; generalised pain; sweating
Sounds great!Rectify
Bluelighter
Same Idea Basically.Rectify
Bluelighter
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ICEY
N-(1-trifluoromethyl-1-trifluoromethylmethyl)-1-phenyl-2-aminopropane
SLURPEE
N-(1-trifluoromethyl-1-trifluoromethylmethyl)-1-(3,4-methylenedioxyphenyl)-2-aminopropane
SEVOSLURANE (inhalation anesthetic)
1-trifluoromethyl-1-trifluoromethylmethyl fluoromethyl ether
TOM_TOMMOROW
N-(2,2,2-trifluoroethyl)-1-phenyl-1-carbomethoxy-2-aminopropane
This Modern World!Rectify
Bluelighter
SE7EN
1-(2-oxo-4-methoxyindan-6-yl)-2-aminopropane
AIGHT
1-(2-oxo-4,7-dimethoxyindan-6-yl)-2-aminopropane
NEIN
1-(2-oxo-7-methoxyindan-6-yl)-2-aminopropane
DOMINO_DANCING aka 'Uncle DD'
1-(1,2,3-trioxoindan-6-yl)-2-methylaminopropane
DOLLY_MADISON
1-(3,4-methylenedioxy-5-methoxyphenyl)-1-carbomethoxy-2-aminopropane
It's A Shame So Many MD-Amps Got Restricted, Such As MDMA.