🌟🌟 Social 🌟🌟 Rectify's molecular poetry thread

[Rectify]

DON_JUAN
1-(3,5-dimethoxy-4-nitrophenyl)-2-aminopropane

 

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BRENT
3-methyl-3-(1-phenylmethyl)-tropane

 

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BRANT
3-methyl-3-(1-(3,4-methylenedioxy)phenylmethyl)-tropane

 

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CAITLIN
3-methyl-3-(1-(3,4-methylenedioxy)phenyloxy)-tropane

 

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ARNOLD
3-methyl-3-(phenyloxy)-tropane

 

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DELUXE
1-carbomethoxy-1-(3,4-dichlorophenyl)-1-(1-(2-(3,4-methylenedioxyphenyl)-1-methylethyl)piperidine-4-yl)methane

 

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DELIGHT
1-carbomethoxy-1-(3,4-methylenedioxyphenyl)-1-(1-(2-(3,4-dichlorophenyl)-1-methylethyl)piperidine-4-yl)methane

 

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DOUBLE_TROUBLE
1-carbomethoxy-1-(3,4-methylenedioxyphenyl)-1-(1-(2-(3,4-methylenedioxyphenyl)-1-methylethyl)piperidine-4-yl)methane

 

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ICE_QUEEN
1-carbomethoxy-1-(3,4-dichlorophenyl)-1-(1-(2-(3,4-dichlorophenyl)-1-methylethyl)piperidine-4-yl)methane

 

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BARE_BONES
1-carbomethoxy-1-phenyl-1-(1-(2-phenyl-1-methylethyl)piperidine-4-yl)methane

 

[Smyth2]

BARE_BONES
1-carbomethoxy-1-phenyl-1-(1-(2-phenyl-1-methylethyl)piperidine-4-yl)methane

I found this could make interesting reading?

1-Phenyl-1-[1-(2-phenylethyl)piperidin-4-yl]butan-2-one

1-Phenyl-1-[1-(2-phenylethyl)piperidin-4-yl]butan-2-one | C23H29NO | CID 12741872 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

pubchem.ncbi.nlm.nih.gov

 

[Rectify]

Ah, Okay. Looks Like They Are Going To Be Opiates.

 

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Compare These 2 Molecules:

ADRENALINE
1-(3,4-dihydroxyphenyl)-2-methylamino-1-(1R)-hydroxyethane

BACARDI_BAT
1-(3,4-methylenedioxyphenyl)-2-methylamino-1-methoxypropane

Now, Apply The False Neurotransmitter Hypothesis. It's A No Brainer! They Are Shaped Similarly.

The N,alpha-methyl Group Makes The N Last Longer, And It Makes The Compound Into An Amphetamine. The Methylene And Methoxy Carbons Make The Compound More Lipophilic. Also, They Make The Drug An Ether. In Order To Cross The Blood Brain Barrier (the pia and dura matters), A Molecule Needs To Be Lipophilic.

 

[Smyth2]

Compare These 2 Molecules:

ADRENALINE
1-(3,4-dihydroxyphenyl)-2-methylamino-1-(1R)-hydroxyethane

BACARDI_BAT
1-(3,4-methylenedioxyphenyl)-2-methylamino-1-methoxypropane

Now, Apply The False Neurotransmitter Hypothesis. It's A No Brainer! They Are Shaped Similarly.

The N,alpha-methyl Group Makes The N Last Longer, And It Makes The Compound Into An Amphetamine. The Methylene And Methoxy Carbons Make The Compound More Lipophilic. Also, They Make The Drug An Ether. In Order To Cross The Blood Brain Barrier (the pia and dura matters), A Molecule Needs To Be Lipophilic.

A good case of where the catechol group is replaced my a methylenedioxy group is for Mdo-npa.

(-)10,11-methylenedioxy-N-n-propylnoraporphine

(-)10,11-methylenedioxy-N-n-propylnoraporphine | C20H21NO2 | CID 13533176 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

pubchem.ncbi.nlm.nih.gov

HCl salt: [81264-57-5]

[1] Ram, Vishnu J.; Neumeyer, John L. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 947 - 949.
[2] John L. Neumeyer, US4543256 (1985 to Northeastern University Boston).
[3] John L. Neumeyer & Sten Ramsby, WO1990012574 (to Northeastern University Boston).
[4] Baldessarini, R. J., Neumeyer, J. L., Campbell, A., Sperk, G., Ram, V., Arana, G. W., Kula, N. S. (January 1982). "An orally effective, long-acting dopaminergic prodrug: (−)-10,11-methylenedioxy-N-propylnoraporphine". European Journal of Pharmacology. 77 (1): 87–88. doi:10.1016/0014-2999(82)90543-X.
[5] Campbell, A., Baldessarini, R. J., Ram, V. J., Neumeyer, J. L. (October 1982). "Behavioral effects of (−)10, 11-methylenedioxy-n-n-propylnoraporphined, an orally effective long-acting agent active at central dopamine receptors, and analogous aporphines". Neuropharmacology. 21 (10): 953–961. doi:10.1016/0028-3908(82)90106-X.

 

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Bounce Is About 2x To 4x As Potent As ICE Methamphetamine On A Milligram To Milligram Basis And Is Sometimes Sold As "Pink Cocaine" For Between $20 And $80 (Or More) Per Gram, Purity Level Unknown. Ideally, Bounce SHOULD Never Be Cut, And New Users Should Be Given Strict Advice On How Many Lines To Do Until They Get The Hang Of It, But You Know How That Goes. Nowhere Fast.

 

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PATRICIA
1-phenyl-1-carbopropoxy-2-methylaminopropane

 

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So, You Want To Reach Nirvana?

ANDREW_23
1-(5-methoxy-indole-3-yl)-2-dimethylaminoethane

From Melatonin.

Dose: 10 mg, vaped.

Having Reached The Spiritual Apex Pinnacle, You Vape 10 mg Of Synthetic Toad Venom, And Your Ego, Having Been Inflated By Countless Stimulant And Entheogenic Substances, Is Shattered. You Experience Ultimate Oblivion. Then, No Longer Being A Spiritual Threat To The Spiritual Superpowers That Be, You Are Free. You Can Choose To Repeat Your Arduous Pilgrim's Progress Or Just Be.

"I'm Going To Destroy My Ego." - Madonna.

"If You Swallowed, Your Own Poison Followed As You CRAWLED Unto The Altar." - Tear Garden.

That Is All.

 

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KETAMIKE
N-hydroxy-2-(2-chlorophenyl)-2-(methylamino)cyclohexanone

 

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CARRIE
N-hydroxy-1-(3-methoxyphenyl)-1-ethylaminocyclohexane

 

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BIS-ESTERIFIED_THC_ANALOG
(6aR,10aR)-1-acetoxy-6,6-dimethyl-9-carbomethoxy-3-pentyl-6a,7,8,10a-tetrahydrobenzo%5bc%5dchromene

From a THC Urinal Metabolite, A Carboxy, Plus A Little Chem.