🌟🌟 Social 🌟🌟 Rectify's molecular poetry thread

[Rectify]

SEMPER_Fi
(3R,4S)-3-methylamino-4-(3,4-dibromophenyl)-tetralin

 

[Rectify]

JOHN_HARVARD
(3R,4S)-3-methylamino-4-(3,4-diiodophenyl)-tetralin

 

[Rectify]

YANG_YANG
(3R,4S)-3-methylamino-4-phenyl-tetralin

YIN_YANG
(3R,4S)-3-methylamino-4-(3,4-methylenedioxyphenyl)-tetralin

YIN_YIN
(3R,4S)-3-methylamino-4-(3,4-methylenedioxyphenyl)-6,7-methylenedioxytetralin

YANG_YIN
(3R,4S)-3-methylamino-4-phenyl-6,7-methylenedioxytetralin

This set of 4 molecules is kind of like a quantum computer with 4 on/off switches.

 

[Rectify]

And Now, For The Truly Brave, There Is

ADVENTURESOME
1-dimethylamino-1-(3-methoxyphenyl)-tetralin

 

[Smyth2]

JASON_HELMS_JONES
1-phenyl-1-methoxy-2-methylaminoethane

This one has a cas number: [104338-27-4].

If you rewind the thread back, it is based on the compounds I already mentioned namely fludorex, SK&F 39728-A & SKF-40652A.

 

[Smyth2]

MUCHISIMO_IMPROVED_ZOLOFT
(3R,4S)-3-methylamino-4-(3,4-dichlorophenyl)-tetralin

All I had to do was shift the methylamino functional group over two carbons.

This one has been done before by Liming Shao of Sunovion.

1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-2-amine

1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-2-amine | C17H17Cl2N | CID 66809019 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

pubchem.ncbi.nlm.nih.gov

He now makes Thevinol/orvinol compounds in j med chem (moved back to China).

 

[Smyth2]

And Now, For The Truly Brave, There Is

ADVENTURESOME
1-dimethylamino-1-(3-methoxyphenyl)-tetralin

This is quite a nice idea to replace the cyclohexanone with a 1-tetralone group.

I also had the same idea for gabapentin & Hexacyclonate. It's also been done before for tramadol.

 

[Rectify]

WOKESOME
1-(3,4-methylenedioxy-5-methoxyphenyl)-1-methoxy-2-aminopropane

On my 'to do' list.

 

[MedicinalUser247]

MUCHISIMO_IMPROVED_ZOLOFT
(3R,4S)-3-methylamino-4-(3,4-dichlorophenyl)-tetralin

All I had to do was shift the methylamino functional group over two carbons.

It's always a good idea to look at other drugs to get ideas.

 

[Smyth2]

That reminds me of another substance made from P2P called H2-Pat [152786-06-6].

1-Phenyl-3-dimethylamino-1,2,3,4-tetrahydronaphthalene

1-Phenyl-3-dimethylamino-1,2,3,4-tetrahydronaphthalene | C18H21N | CID 10015055 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

pubchem.ncbi.nlm.nih.gov

 

[MedicinalUser247]

This is Rectify in the future. lol.

 

[Rectify]

He Who Controls The Spice Controls The World.

The Spice Is Right!

 

[Smyth2]

methyl 3-amino-2-phenylpropanoate [99092-02-1]

CH369764A - Process for the preparation of new a-aryl-w-amino-alkanoic acids and their derivatives - Google Patents

Add a para-fluoro and get this:

Methyl 3-amino-2-(4-fluorophenyl)propanoate

Methyl 3-amino-2-(4-fluorophenyl)propanoate | C10H12FNO2 | CID 82125876 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

pubchem.ncbi.nlm.nih.gov

 

[Rectify]

SHINY_DISCO_BALLS
1-(3,5-dimethoxy-4-(1-oxa-2-oxohexyl)phenyl)-2-aminopropane

From syringealdehyde (3,5-dimethoxy-4-hydroxybenzaldehyde).

 

[Rectify]

BABY_PUMA
1-(4-isopropylphenyl)-2-aminopropane

from cuminaldehyde

You kinda have to do a good bit of this one to see its particular magic, but it is there.

 

[Smyth2]

BABY_PUMA
1-(4-isopropylphenyl)-2-aminopropane

from cuminaldehyde

You kinda have to do a good bit of this one to see its particular magic, but it is there.

I always used to called this cumphetamine [32560-62-6]. The aldehyde is sometimes known as "cuminal".

 

[Rectify]

Haha, gross!

THE_PUNDING_PUNDIT
N-chloro-1-phenyl-1-carbomethoxy-2-methylamino-propane

 

[Rectify]

SMYTH2
1-phenyl-1-carbomethoxy-2-methylamino-3-hydroxypropane

It's a Cross Between BOUNCE and GHB.

 

[Smyth2]

SMYTH2
1-phenyl-1-carbomethoxy-2-methylamino-3-hydroxypropane

It's a Cross Between BOUNCE and GHB.

I can see the logic is based on PAL-329 [5267-64-1].
This weak stimulant can be used in the synthesis of Solriamfetol.

 

[Rectify]

G3
1-(4,7-dimethoxy-5-indanyl)-2-aminopropane

"Would I Venture Out To The Mailbox Like
This. No Ever Loving Way!" - from PiHKAL: A Chemical Love Story By Alexander & Ann Shulgin.