“The Amphetamines are particularly notorious for their ability to enduce a state of pleasurable effects, elation and euphoria, and are therefore highly abused substances “ medical journal excerpt
Desoxyn (Methamphetamine) and Vyvanse (Lisdexamfetamine) are also effective treatments for narcolepsy. Methamphetamine is potent and long acting but has the greatest abuse potential
d-Methamphetamine >d-Amphetamine>MPH - Ritalin> Modafinil
Dextro-Amphetamine (Dexedrine) is also used recreationally as a euphoriant and aphrodisiac, and like other amphetamines is used as a club drug for its energetic and euphoric high”
Ritalin (Methylphenidate) 50-70mg IR + Methadone 100mg has been my morning Speedball for 20+ years (plus benzodiazepine, Gabapentinoid, Ethanol, Nicotine) …..Ritalin gave me VERY robust euphoric bliss when I started taking it…..same euphoric bliss as Opoioids (especially Oxycodone)
Oxycodone or Diamorphine/Dilaudid mixed with Dexedrine/Adderall/Ritalin/Desoxyn is the most euphoric combination pharmacology has even seen……endorphines & monoamines DAT/NET/SERT = Euphoric bliss
People have always loved their Amphetamines…..Ritalin is my personal favourite
Benzedrine, Dexedrine, Methedrine
Phenmetrazine
Methylphenidate
Cocaine
Benzphetamine (pro-drug, metabolizes into d-Meth, then into d-Amph)
Pemoline
Benzphetamine (Didrex) is still prescribed for obesity & narcolepsy……it’s essentially Desoxyn (Methylphenidate) but with a lower scheduling SCIII ……Didrex in-vivo metabolizes into d-Methamphetamine and further into d-Amphetamine. Some doctors might hear Didrex and not feel same stigmatized status as Desoxyn (d-Meth)
Adderall 30mg XR is great
Dexedrine Spansule 15mg are great whole or pulverized into IR powder (like Adderall XR beads)
Ritalin & Focalin are excellent dopaminergic stimulants capable of inducing strong euphoria
Desoxyn while available, is rarely prescribed as its Desoxyephedrine HCL (d-Methamphetamine) and most prescribers would opt for Dexedrine, Vyvanse, Adderall, Ritalin etc
I LOVE the onset & C-Max of my Methylphenidate IR 50-70mg in combination with my Methadone as it’s Ohhh Sooo Pleasurable and just pure sex inside my CNS