jkyl
Bluelighter
http://books.google.com/books?id=9c_gAAAAQBAJ&pg=PT207&lpg=PT207&dq=clonazepam+rectal+tmax&source=bl&ots=dwRJE-OrjO&sig=-9_RyLsfp0F4tDxNb5E8g4AXM1o&hl=en&sa=X&ei=o7xdVPviBJDksAT89oHoDg&ved=0CDAQ6AEwBTgK#v=onepage&q=clonazepam%20rectal%20tmax&f=false
This is an excerpt from a book I found while searching google for the Tmax of various ROA's for clonazepam, but it yielded some unexpected information. Apparently benzos are absorbed more rapidly via insufflation (assuming enough of the active compound finds some membrane despite all the binders/fillers in pills) than when simply ingested. This disputes many BLer's stalwart defense of insufflation providing mostly placebo plus primary effects when the drip reaches one's stomach.
I am in no way suggesting that this is the best way to get the most out of your benzos given their [almost] unanimously 80-90%+ oral bioavailability, and certainly not condoning snorting pills with all the negative effects that go along with that ROA. However, I know many of us do it and will continue to do it, but I feel obligated to remind everyone that snorting shit IS bad for you in the long run for HR purposes.
Do with this information what you will. I simply thought it was interesting and contrary to many highly held beliefs about benzo use. Knowledge is power, but please use it wisely.
-jkyl
This is an excerpt from a book I found while searching google for the Tmax of various ROA's for clonazepam, but it yielded some unexpected information. Apparently benzos are absorbed more rapidly via insufflation (assuming enough of the active compound finds some membrane despite all the binders/fillers in pills) than when simply ingested. This disputes many BLer's stalwart defense of insufflation providing mostly placebo plus primary effects when the drip reaches one's stomach.
I am in no way suggesting that this is the best way to get the most out of your benzos given their [almost] unanimously 80-90%+ oral bioavailability, and certainly not condoning snorting pills with all the negative effects that go along with that ROA. However, I know many of us do it and will continue to do it, but I feel obligated to remind everyone that snorting shit IS bad for you in the long run for HR purposes.
Do with this information what you will. I simply thought it was interesting and contrary to many highly held beliefs about benzo use. Knowledge is power, but please use it wisely.
-jkyl