Benzos providing ammunition for the "to snort or not to snort" debate about benzos

[jkyl]

http://books.google.com/books?id=9c_gAAAAQBAJ&pg=PT207&lpg=PT207&dq=clonazepam+rectal+tmax&source=bl&ots=dwRJE-OrjO&sig=-9_RyLsfp0F4tDxNb5E8g4AXM1o&hl=en&sa=X&ei=o7xdVPviBJDksAT89oHoDg&ved=0CDAQ6AEwBTgK#v=onepage&q=clonazepam%20rectal%20tmax&f=false

This is an excerpt from a book I found while searching google for the Tmax of various ROA's for clonazepam, but it yielded some unexpected information. Apparently benzos are absorbed more rapidly via insufflation (assuming enough of the active compound finds some membrane despite all the binders/fillers in pills) than when simply ingested. This disputes many BLer's stalwart defense of insufflation providing mostly placebo plus primary effects when the drip reaches one's stomach.

I am in no way suggesting that this is the best way to get the most out of your benzos given their [almost] unanimously 80-90%+ oral bioavailability, and certainly not condoning snorting pills with all the negative effects that go along with that ROA. However, I know many of us do it and will continue to do it, but I feel obligated to remind everyone that snorting shit IS bad for you in the long run for HR purposes.

Do with this information what you will. I simply thought it was interesting and contrary to many highly held beliefs about benzo use. Knowledge is power, but please use it wisely.

-jkyl

 

[EarthBounded]

Insufflation of pure alprazolam powder or etizolam powder it very powerful IME. However in a typical xanax pill you have 1mg alpraz and 100mg+ binder and filler, I have never weighed one out. Its very hard to get that all up the nasal passage before sneezing just not worth it. The pure powders are very powerful up the nose but very dangerous especially when mixed.

 

[ChemicalSmiles]

WASTE OF TIME ! i

 

[smackydowners]

yeah, this is for quickly treating seizures in a medical emergency using pharmaceutical grade sprays, not crushed tablets. very different

 

[The Doc.]

^°^he's right in a medical setting they would never crush up a tablet then tell a patient to snort it they use a very potent liquid solution to squirt up the nose so their wouldn't be all those binders and fillers screwing with the absorption.

I think we should agree crushing up pressed benzodiazapine tablets and snorting them is a waste and causes unnecessary harm to the user.

Thanks for the info but its still not practical to snort benzos when they are in pill form.

Im going to close this now.