potentiating benzos

[sneakdiss]

It takes me like 6 mg's of clonazepam to even feel anything. (without alcohol of course)

 

[LeadSingerDisease]

that's great, but I'm talking about KLONOPIN, CLONAZEPAM. Grapefruit won't work for that, besides it's dissolved on your toungue.

Ok first of all, pills are meant to be swallowed. But either way, whether you swallow it or let it dissovle under your tongue its still gonna end up in your body the same way. Just at different speeds. And also, I found many resources saying that grapefruit juice will work for all benzo's.

 

[troublemaker_420]

.25 mgs? I can't think of anything that could potentiate that to a decent high. I've only messed around with Klonopin a few times (wife has a script) and its taken at least 1.5 mgs to do much of anything, and thats usually helped out with a drink or two or some herb. I don't think you'll get much from .25 mg myself.

 

[paradoxcycle]

wtf has become of OD?

I know man, jesus fucking christ, these greenlighters!

 

[digital_phreedom]

chug grapefruit juice.. i do it before almost every worthwile drug i do..

hydrocodone
oxycodone
benzos
ecstasy
mushrooms

i have personal experience with it increasing rolls, and opiates at least two-fold

 

[Nullific]

Ok first of all, pills are meant to be swallowed.

Yes, pills are meant to be swallowed...but I think hes talking about the benzos in waffer-form that are made to be dissolved in your mouth. (not swallowed)

If thats the case it'll probably disolve before you get it far enough up your ass.

 

[soundphaRm]

wtf has become of OD?

Yes, Naturalone, I ask myself the same thing a lot...nice to "see' you on here again, though...I've been away doing my clinicals for my M.S. in Nursing, so I haven't been around for awhile...

If the pill is designed to be sublingual (under the tongue- and yes it does matter if it's on top of your tongue, as opposed to actually under it), you should take it that way. That's the best way anyway, next to injection/insufflation, neither of which are an option in your case due to solubilty issues.

Put it under your tongue and let it dissolve completely.
As far as potentiation goes, about 1-2 hours before you want to take it, take 200-300 mg of cimetidine (AKA- Tagamet). Tagamet inhibits the enzyme responsible for the metabolism of clonazepam, CYP 450(3A4), thus allowing it to persist in your plasma for longer periods of time.
It works well (from experiece)...also, chug the Tagamet (1 or 2), and the following clonazepam down with some regular (not the pink or Ruby Red) grapefruit juice. It can't hurt...Hope this helps 'ya out...

Cheers- soundphaRm

 

[troublemaker_420]

As far as potentiation goes, about 1-2 hours before you want to take it, take 200-300 mg of cimetidine (AKA- Tagamet). Tagamet inhibits the enzyme responsible for the metabolism of clonazepam, CYP 450(3A4), thus allowing it to persist in your plasma for longer periods of time.

Interesting....I never knew that tagamet could do this.....thanks for the info!

 

[sp0r]

wow

Bro .25 probably isnt going to get you a buzz no matter which way u slice it. But I cant believe that no one knew that cimetidine will work well with klonopin. Also diphenhydramine. The diphenhydramine potentiates it, and the cimetidine is a cyp3a4 enzyme inhibitor which allows more to be in your blood stream for a longer period of time. Cimetidine is a heartburn medication called Tagamet in the us. But dont think that other heartburn meds will work. Only cimetidine pulls this magic. ALSO opiates/opiods have a potentiating synergy with benzos. Opiates are probably the best opiod potentiator and vice versa but if you are looking for a longer buz take the cimetidine an hour before ingesting your pills and the opiate/diphenyhradime a half hour before.

Bon Apetit!
sp0r B

 

[sp0r]

Oh I apologize I didnt see some of the posts on the second page. But I still reinforce the fact that cimetidine works for SOME benzos but not all. The best thing you can do is go to your drug store, and get a book called "The Pill Book" and right now I think its in its 13th edition. What you want to do is look up your drug and go to the drug interactions page. If it has cimetidine listed as a drug interaction it works for that benzo. Benzos are complicated because some of them have active metabolites and some of them dont, and some of them arent even metabolized by cyp3a4

 

[sp0r]

benzos

It takes me like 6 mg's of clonazepam to even feel anything. (without alcohol of course)

It suprises me to see that most of bluelist is concerned with benzos. Its hard to discuss because the doseage range is crazy. Some people get smashed off a .5 clonazepam, I just ate 20mg's of clonazepam (.5mg tevas and 1mg klonodina), Im eating lorazepam now but trying to figure out how to make it stronger other than grapefruit juice. I took 3 tagemets already. I only have 8 if I had more id eat the whole bottle. But Ive heard of people hallucinating off of lorazepam and Im trying to make that happen. Im also trying to figure out what is the true scientific answer about lorazepam and clonazepam, under the tongue or down the hatch (swallow). Im always afraid to swallow because if I have a bunch of food in my stomach then I am worried the tiny amount of a couple of milligrams wont make it to my blood stream. Does anyone know about this. Im getting pretty damn high off the 20mgs of klon which is usually dont, maybe the lorazepams are potentiating them. If some one reads this and knows of a thread where I can find info on making lorazepam more potent or last longer (BESIDES CIMETIDINE) everyone in the world knows about tagamet. But I would appreciate it. They usaually work good sublingual but they whear off quick. I have eaten several loraz already and I need to know what to do with the extra 8. Thaks for the help
spizzizz0r

 

[gorgoroth]

it's meant to be absorbed in your mouth. I'm wondering if putting it under my toungue or my ass would make it hit me any stronger. Dont' have any grapefruit or orange juice. what should I do?

for clonazepam? grapefruit doesn't has as much an effect on it then other benzos such as diaz and triazolam. but large amounts of grapefruit juice potentiate clonazepam to a degree, alcohol does to a great degree.

 

[sakrik]

every med books says that clonazepam is most powerful benzo, but not for me, i had over 50 2mg's Rivatril pills (Rivatril name only in Finland i think, usually Klonopin etc). If i took 4mg Clonazepam it feels like something like 10mg Diazepam, Diazepam is good anxiety and relaxant for me. But every equilevancy tables says 0.5mg clonaze = 10mg diazepam, this is weird, coze i have really take 4mg clonazepam that i feel a thing.. something naturally tolerance to clonazepam or what, all other benzos works fine me and much lower doses than clonaze.