hi there, I'm new to this forum so sorry if this is in the wrong place. i apologise if it is long, but id imagine this is a question/ theory many people won't have heard before
i want to discuss phenibut. i know phenibut is a form of gaba that has an extra phenyl ring bonded to it, allowing it to cross the blood brain barrier.
i went to a natural doctor with general anxiety all the time and over-stimulation. I'm always hyped up, can't relax etc.
he did a urine neurotransmitter test, the results showed low gaba levels, and high adrenaline levels. i went to the doctors after this, they did tests and said i has no medical reasons for this, no tumours etc. i know urine neurotransmitter tests aren't accepted as accurate by some, but the results matched my symptoms very well, i did 2 more urines neurotransmitter tests under different names, and they all came back the same, with the low gaba and high adrenaline. so i do believe they are accurate.
i have been put on amino acids and herbs to gradually replenish my levels. however it'll obviously take a fair amount of time, but i want to properly balance myself out and return to normal, not be drug dependant forever.
now i know a lot of people take phenibut for my issues, and they say it is very very good and can relief anxiety and over-stimulation completely. but a quick tolerance develops. however, i think i know why. we are dosing far far far too high. most people want instant relief. they want their symptoms to be fully gone within hours of taking the pills, so this is why doses of 500mg-2 grams are advised. this delivers a huge amount of gaba to the brain, shutting down all anxiety. but obviously tolerance develops.
in my opinion I'm not surprised. now i don't know how much gaba a healthy brain will make, but i know for sure it is nowhere near 2 grams. or even 500mg. by overloading your brain with gaba, it will obviously down regulate receptors to compensate.
id guess the brain makes a fraction of this amount of gaba per day in healthy individuals with no anxiety. id love to know the exact amounts, but lets says the brain only makes about 20-30mg of gaba per day. anything more will cause down regulation, tolerance, withdrawals, and also stop natural gaba production because the brain is fooled into thinking the body has adequate gaba.
naturally restoring gaba levels is tricky, because once gaba is low, adrenaline becomes very high as there is nothing to counter it. now every time gaba is made, it is instantly used to try bring down the high adrenaline, so it isn't allowed to accumulate and replenish. so what i was thinking is. if i provide myself a very very low dose of phenibut daily, say 20mg-30mg, this will simply just replace what gaba is missing, maybe even provide a little boost in gaba but still leave me somewhat deficient. this way, the adrenaline can be calmed down slightly, to allow gaba to naturally start replenishing and accumulating, but at the same time, the receptors won't be overwhelmed by huge amounts of gaba and down regulate, it'll lead to no tolerance, and no withdrawals, even when taken daily.
most people would never dose this low, because you are likely to not even feel its effects, well not at first anyway. people want instant relief of symptoms, not to actually cure themselves.
for example 2 grams of phenibut lets say lowers adrenaline by 70% after one dose, this causes huge reductions in anxiety, but the huge amount of gaba the receptors are given makes them down regulate and this leads to all the negatives and means it can't be taken daily, it also completely stops natural gaba production because the brain thinks it has enough.
however, the tiny 30mg dose maybe only lowers adrenaline by 1% at a time. so 1 % a day. this will likely not even be felt at all. people will be unsatisfied and say it is a waste of time. but, after 10 days your adrenaline will be 10% lower, still maybe not enough to have less anxiety, but you're making a dent. after 20 days its 20% lower and after 30 days you have 30% less adrenaline. you may now be feeling a reduction in anxiety. after 2 months, your adrenaline would be 60% lower, this is when you would see huge improvements in anxiety. but, at the same time, it is sustainable, your brain receptors are only receiving a normal healthy amount of gaba that it should be receiving from a healthy brain, so receptors do not down regulate, just like they never down regulate in any normal person with no anxiety who produces all the gaba he needs himself.
along side this low dose phenibut, you are supplementing all the amino acid building blocks for natural gaba production ( l glutamine, taurine, theanine, vitamin b6, zinc, magnesium etc) so your natural gaba levels are replenishing and accumulating, while not being used up from the constant demands of high adrenaline, because the phenibut is taking the workload.
over time, your gaba levels will build up back to normal, it is then that you can discontinue the phenibut supplement, and your body has huge stores of natural gaba it can use to counter stress. basically, your brain chemistry is back rebalanced and you are cured.
i was just wondering what peoples opinions were on this?
would you likely develop tolerance to phenibut with tiny tiny doses of 20-30mg a day ( usual dose is 500mg-2000mg). or should you be fine?
this is similar to the kalish method for fixing adrenal fatigue. you supplement tiny tiny amounts of rhea and cortisol, basically replacing what the body is missing but not going over, then over time as your body balances you discontinue the supplements are you're back to functioning on your own.
thanks for reading, i know it was a long post but i think this is a question you likely won't have heard before.
i want to discuss phenibut. i know phenibut is a form of gaba that has an extra phenyl ring bonded to it, allowing it to cross the blood brain barrier.
i went to a natural doctor with general anxiety all the time and over-stimulation. I'm always hyped up, can't relax etc.
he did a urine neurotransmitter test, the results showed low gaba levels, and high adrenaline levels. i went to the doctors after this, they did tests and said i has no medical reasons for this, no tumours etc. i know urine neurotransmitter tests aren't accepted as accurate by some, but the results matched my symptoms very well, i did 2 more urines neurotransmitter tests under different names, and they all came back the same, with the low gaba and high adrenaline. so i do believe they are accurate.
i have been put on amino acids and herbs to gradually replenish my levels. however it'll obviously take a fair amount of time, but i want to properly balance myself out and return to normal, not be drug dependant forever.
now i know a lot of people take phenibut for my issues, and they say it is very very good and can relief anxiety and over-stimulation completely. but a quick tolerance develops. however, i think i know why. we are dosing far far far too high. most people want instant relief. they want their symptoms to be fully gone within hours of taking the pills, so this is why doses of 500mg-2 grams are advised. this delivers a huge amount of gaba to the brain, shutting down all anxiety. but obviously tolerance develops.
in my opinion I'm not surprised. now i don't know how much gaba a healthy brain will make, but i know for sure it is nowhere near 2 grams. or even 500mg. by overloading your brain with gaba, it will obviously down regulate receptors to compensate.
id guess the brain makes a fraction of this amount of gaba per day in healthy individuals with no anxiety. id love to know the exact amounts, but lets says the brain only makes about 20-30mg of gaba per day. anything more will cause down regulation, tolerance, withdrawals, and also stop natural gaba production because the brain is fooled into thinking the body has adequate gaba.
naturally restoring gaba levels is tricky, because once gaba is low, adrenaline becomes very high as there is nothing to counter it. now every time gaba is made, it is instantly used to try bring down the high adrenaline, so it isn't allowed to accumulate and replenish. so what i was thinking is. if i provide myself a very very low dose of phenibut daily, say 20mg-30mg, this will simply just replace what gaba is missing, maybe even provide a little boost in gaba but still leave me somewhat deficient. this way, the adrenaline can be calmed down slightly, to allow gaba to naturally start replenishing and accumulating, but at the same time, the receptors won't be overwhelmed by huge amounts of gaba and down regulate, it'll lead to no tolerance, and no withdrawals, even when taken daily.
most people would never dose this low, because you are likely to not even feel its effects, well not at first anyway. people want instant relief of symptoms, not to actually cure themselves.
for example 2 grams of phenibut lets say lowers adrenaline by 70% after one dose, this causes huge reductions in anxiety, but the huge amount of gaba the receptors are given makes them down regulate and this leads to all the negatives and means it can't be taken daily, it also completely stops natural gaba production because the brain thinks it has enough.
however, the tiny 30mg dose maybe only lowers adrenaline by 1% at a time. so 1 % a day. this will likely not even be felt at all. people will be unsatisfied and say it is a waste of time. but, after 10 days your adrenaline will be 10% lower, still maybe not enough to have less anxiety, but you're making a dent. after 20 days its 20% lower and after 30 days you have 30% less adrenaline. you may now be feeling a reduction in anxiety. after 2 months, your adrenaline would be 60% lower, this is when you would see huge improvements in anxiety. but, at the same time, it is sustainable, your brain receptors are only receiving a normal healthy amount of gaba that it should be receiving from a healthy brain, so receptors do not down regulate, just like they never down regulate in any normal person with no anxiety who produces all the gaba he needs himself.
along side this low dose phenibut, you are supplementing all the amino acid building blocks for natural gaba production ( l glutamine, taurine, theanine, vitamin b6, zinc, magnesium etc) so your natural gaba levels are replenishing and accumulating, while not being used up from the constant demands of high adrenaline, because the phenibut is taking the workload.
over time, your gaba levels will build up back to normal, it is then that you can discontinue the phenibut supplement, and your body has huge stores of natural gaba it can use to counter stress. basically, your brain chemistry is back rebalanced and you are cured.
i was just wondering what peoples opinions were on this?
would you likely develop tolerance to phenibut with tiny tiny doses of 20-30mg a day ( usual dose is 500mg-2000mg). or should you be fine?
this is similar to the kalish method for fixing adrenal fatigue. you supplement tiny tiny amounts of rhea and cortisol, basically replacing what the body is missing but not going over, then over time as your body balances you discontinue the supplements are you're back to functioning on your own.
thanks for reading, i know it was a long post but i think this is a question you likely won't have heard before.
