Jeez. Never done methadone to be fair. The other day my friend took 80mg Oxy in one go and was puking for 2 days. I’ve only got sick once from taking 600mg codiene (300mg after the first 300 wore off) when I was about 17. Woke up with the worst headache I’ve ever had in my life, couldn’t even stand up and was puking green bile all day. Would be interested to know what the neurobiology is behind opioid ‘hangovers’ as it’s something that isn’t really discussed anywhere as far as I’ve seen. I was convinced I’d given myself liver damage or something