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Opioids Oxycodone reaction, help is appreciated

S

SoFarAway

Greenlighter
Joined
Dec 23, 2010
Messages
14
Hello all, my name is Angela and I'm twenty-one.

I'm prescribed Roxicodone and Percocet for break-through pain relief. We're talking 5mg here, so small that it never gets rid of all the pain. It's what I take, though, so I'm obviously not very hardcore lol

I first took Oxycodone after my wisdom teeth were removed in 2007. It almost killed me in the beginning, to be honest. I was knocked out very quickly, but I woke up in a gasp my heart was pounding and I was covered in sweat. After that first mishap, I was fine. I had surgery in 2008 and was given more Oxycodone as I was discharged. I got to where I could take it without falling asleep, but it also was able to help me fall asleep at night. In a sense, it was rather perfect.

Fast-forward to the end of 2009. I'm dealing with ovarian cysts and two herniated discs in my lower back. Something starts to go wrong each time I take Oxycodone. First, I get insomnia. Second, and most importantly, I get sleep paralysis. Every. Single. Time. And it's terrifying!! Sometimes there's auditory hallucinations with the sleep paralysis.

The weirdest thing is, I'll take the 5mg of Oxycodone at 3pm... and when I'm going to sleep eight hours later, THEN these symptoms start. If I lie down at 4pm I'm nice and peaceful, I have less pain. The insomnia is still there, but there's no sleep paralysis.

I finally broke down after a horrible night and called the hospital pharmacist. He said that what I'm experiencing should not be happening and I'm having a reaction. Does anyone know what's causing this, though? What's happened to me? I'm going to have to take this medicine again before I meet with my doctor and I get so scared each time I have to take it.

As background, I do have a bunch of health issues. Could an elevated protoporphyrin level cause this? Liver disease? No gallbladder?

I have no idea what has suddenly happened.

Thanks for reading :)
 
This is just weird. You said the side effects hit you 8 hours after your dose? The only reasonable explanation I can think of is withdraw, which wouldn't make sense cause you never really took enough to get addicted. But I always get sleep paralysis whenever I'm withdrawing, real bad too. If the problem only occurs when you take your dose 8 hours before sleep, why not just take it later in the day? Try one before bedtime.

It could just be an allergic reaction, which you don't need to worry too much about considering there is a huge range of various opiates. My only suggestion is don't let the doctor put you on MS Contin; that seems to be the DOC for most doctors now and it stinks because the oral bioavailability is really low.


I'm interested to see what other people have to say about this.
 
I experience the EXACT same thing when I take Oxy during the day and try to sleep later that night. Happens with roxi's, OC, and the new OP.

Last Thursday:

6AM dose with ~40mgs

All day, felt a great opiate buzz. Really enjoyable. That night, around 10PM, I can't sleep. Typical insomnia I get with opiates. As I lay in bed, I get this tremendous feeling in my body, it feels like a "body high" if you will. This in itself is bliss. Again, this happens EVERY night after I take oxy at some point during the day. However, there's a dark side. Soon after, I fall into sleep paralysis and the horror that accompanies it ensues.

I get audio and visual hallucinations, typically it's a female voice calling to me or a woman walking up my stairs towards my bed. I can't move. Period. She starts screaming my name and I'm utterly horrified. I hear other whispers and voices and eventually I thrash my body about to wake myself. When I do, I'm covered in sweat, heart racing, totally terrified of falling back asleep. If I don't move around, I instantly fall back asleep INTO THE EXACT SAME NIGHTMARE. Seriosly, it's identical. Starts off with whispers, woman comes upstairs, and I'm freaking out. I've tried taking control of the dream, as I'm lucid, and it only ends the same way.

This is by far the scariest thing I've ever experienced. It's no joke and certainly isn't any fun. If you don't "get" it, then props. You're not missing out. I wish I didn't. Again, I only get this when I do oxy, it's reason enough to stop. If it's withdrawal, then that's even more of a reason to stop. No biggie. I can live without oxy and I'd rather live without the panic inducing nightmares that accompany sleep paralysis.
 
you dont have to take it try a night with out it. have you?.you might have a tolerance and taking it at 5 than 8 hours later maybe coming down and a sign of withdrawl?
 
You could try using a first generation antihistamine, like promethazine, doxylamine succinate, diphenhydramine, etc... as a sleep aid. It might keep you asleep through the night better and help you avoid the sleep paralysis. They are often used to potentiate opioids. They might make you feel groggy the next morning though.

As someone else suggested, you could also try not taking the 3pm dose and instead take it before sleep.

Next time you see your doctor, talk to him about it and see what the options are.
 
ive got to say that you would most likely have the same or worse reaction on other Thebaine derived opioids;
oxy, dilauded, fentanyl.

my wife and i both also have mediocre paradoxical effects on these drugs. dilauded seems more gentle, but in the long run idk, fentanyl i would refuse because of my reaction to oxy, i figured fentanyl would probably have a greater stim affect.

morphine is very agreeable with me, methadone has a perk to it in me, but nothing distracting...

read about Thebaine; important info for your daily life living.

:)
 
I don't have time to post a well thought out post, as I was about to walk out the door when I saw this but.....

I'm a pain-killer addict and I pretty much always use Opana. When I first started Opana, similar to you with oxycodone, it helped me sleep like a baby. I've had trouble sleeping for as long as I remember and opiates solved that problem for me at first. I use to love nothing more than taking my DOC and drifting quickly off to a comfortable sleep and wake up refreshed.

That only lasted for so long though(6-8 months), now when I take Opana, I sleep in a very 'paranoid' state(if I can fall asleep at all). As soon as i feel myself starting to dose off, I'll snap back out of it or jump up thinking I'm not alone in my room(odd I know). Anyways, I saw you mention sleep paralysis, and I too have been experiencing that when taking pain meds before bed. I've had sleep paralysis maybe 2-3 times TOTAL in my lifetime before I took opiates, but now I find myself having it extremely often (almost everytime I take opiates and try to sleep). When I don't take opiates, I sleep mostly comfortably and pretty much never experience sleep paralysis. To put it shortly, what use to solve my sleep problems (pain meds), now does nothing but amplify them. I also will find myself doing this wierd shaking thing almost like a seizure in my sleep and I think when I don't wake up from the shaking it usually leads to an episode of sleep paralysis.

Anyways, sorry about the sloppy post and the fact that I didn't offer any solutions as I'm in a hurry, and because I have no solutions. I just wanted you to know you aren't alone with some of your issues and you are the first one I've found to have similar issues to me concerning opiates and sleep.

I know I'll let you know if I find a solution to the problem, and I hope you'll do the same.

Good Luck.


edit: I'd also just like to add that the other night on opiates I had for the first time of my life a "movie-esque" nightmare..... the type where you wake up sweating, jump up, and scream NO!. It fucked with me enough to make me get up at 3am and watch tv and chillout for abit before going back to bed. I've had many many nightmares in my life, but none as crazy as this one.
 
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I have experienced sleep paralysis, and very "vivid" dreams on the few occassions I was able to get my hands on oxy. I thought opiates were fairly known for these effects.
 
^ There are higher rates of sleep apnea in patients using opioid analgesics. Link.

Sleep apnea is different to sleep paralysis though. Wikipedia includes lucid dreaming on it's list of possible causes of sleep paralysis, but there is no reference for that claim and I can't find much via my short Google search session.
 
your 21 and you had your wisdom teeth out when you were 18 ? thats pretty young to have them out, in fact never heard of anyone having them out at that age, thats pretty unlucky. on the no sleep side thats pretty comman for sum one who has not been taking opiates every day for long periods, seems to hype you up a bit when you first start then after awhile you just end up with no energy.
 
at 17 i had one wisdom tooth pulled, and two surgically removed, the other was to embedded, and almost totally horizontal like the later 2.

i had a lil speed ball fixation at the time, and tried to prepare my arms as i knew i was being anesthetized, so i tried to only hit in my right arm crook.
thats the first place they went, the nurse saw and got the doctors to come over, they went lower started pumping the stuff in, and i started blabbing.
"you guys are going to have a hard time knocking mgr out"
then i woke up blabbing like a damn fool...


sorry, had to share hehe, i love stories of anastasia- c omic-relief...
i got pretty damn silly a few months ago after some "milk of anastasia", versed, and fentanyl.
in short, "you make Eggs Benedict from Scratch"!?!
patient pointed at nurse, had a crooked eye look of delight and then demanded out loud:
"Giiive me your recipe"!:-o!

ohmaaan.
;)
 
I'm so sorry, everyone. I really appreciate the replies! Somehow I must not have clicked the button that sent me emails with updated posts. I am new here... :)

It seems like I'm not alone with my issues, so that at least makes me feel better. I wish the sleep paralysis didn't happen to others, though, since it truly is terrifying. I used to have lucid dreams right before the sleep paralysis which was never a bad thing. I had this one night where I dreamed I was on a boat with Morris the Moose haha Those fun experiences stopped about eight months ago, though, and now there's no lucid dreaming, just straight terror.

Panic in Paradise, your post was very interesting to me because I had awful insomnia with Dilaudid. How does that happen? One injection made me so dizzy I couldn't open my eyes for hours. I just laid there hoping for sleep that did not come. The only thing I can think is, I had taken Oxy earlier in the day. Maybe it was the Oxy still doing what it always does to me. I definitely will look up thebaine, though. (Also, I had a horrible reaction to Versed! lol I became violent and totally nuts. I was told "We had to give you eight times the normal dose to get you back to sleep. One more dose would have killed you." O_O I am totally, absolutely, completely, positively in love with Propofol. I'd marry it.)

Wussmonster, I understand completely what you're saying. I take the meds for pain and I'd rather have pain than sleep paralysis. Any day.

Adubwakka, you're post sounds a lot like what I went through with the drugs being sedating a wonderful at first, and then turing into something all together. I appreciated your reply and I'm really sorry about what you're also experiencing.

My wisdom teeth were severely impacted. I was put completely out for the surgery and they ended up having to remove a bone tumor from my mouth where an impacted wisdom tooth was pressing into a molar so forcefully. Tumor was non cancerous, thank God. The pain was just awful afterwards, though. Now, with herniated discs, I have more pills.

I actually tried someone's Vicoprofen a couple or days ago and it was pretty perfect. Took away all the pain and, after some time of my mind going into overdrive (this happens with me and opiates), I fell right to sleep and felt tired all day. No trouble sleeping at night. I think I found a new best friend in hydrocodone.
 
Hallucinations esp at night are a side effect of opiod use.

sometimes i get crazy thoughts in my head and it seems as if im not in control of my thoughts. just push past it and dont let it become a big deal u'll nod off eventually.
 
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