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OTC treatment for opiate overdose?

^Dankaholic, I can completely understand that FOR YOU... but I am talking about as a society this is something worth looking into.

In Boston, in 15 months time 74 overdoses were reversed with narcan nasal spray... those people wouldn't have had vials of narcan they swiped from a hospital lying around, those people very well could have died. Also, to reiterate the conclusion of the second study, "Problems with intranasal naloxone were uncommon. Overdose prevention education with distribution of intranasal naloxone is a feasible public health intervention to address opioid overdose. "

I understand why YOU would prefer your method given your training and resources, but what say you about NEPs giving classes on using these sprays and distributing them to heroin/opiate users? I think this could have a demonstrable effect on overdose deaths if applied throughout.

And in regards to your issue with dose; I don't doubt that IM/IV can be more precise but are you familiar with the mechanism these particular devices dispense with? Have you read the studies to see if this was ever brought up as a factor? I could be wrong, but it appears to me that your issue with dose is speculation on your part. Even if there was some small variability in dose, if I OD'd I'd rather be given this while I'm waiting for the ambulance then lay there unconscious.

Lastly, you flat out said that nasal sprays would not work, I just wanted to demonstrate (which I think I did thoroughly enough) that was a fallacious claim.
 
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i think it should also be said that its damn near impossible (like 200 times the average dose) to OD on naloxone so i really don't think you need to be precise, just give a lot for good measure.
 
^Right, and in the training they provide when they give these sprays out, I'm pretty confident they address these issues.
 
^Dankaholic, I can completely understand that FOR YOU... but I am talking about as a society this is something worth looking into.

In Boston, in 15 months time 74 overdoses were reversed with narcan nasal spray... those people wouldn't have had vials of narcan they swiped from a hospital lying around, those people very well could have died. Also, to reiterate the conclusion of the second study, "Problems with intranasal naloxone were uncommon. Overdose prevention education with distribution of intranasal naloxone is a feasible public health intervention to address opioid overdose. "

I understand why YOU would prefer your method given your training and resources, but what say you about NEPs giving classes on using these sprays and distributing them to heroin/opiate users? I think this could have a demonstrable effect on overdose deaths if applied throughout.

And in regards to your issue with dose; I don't doubt that IM/IV can be more precise but are you familiar with the mechanism these particular devices dispense with? Have you read the studies to see if this was ever brought up as a factor? I could be wrong, but it appears to me that your issue with dose is speculation on your part. Even if there was some small variability in dose, if I OD'd I'd rather be given this while I'm waiting for the ambulance then lay there unconscious.

Lastly, you flat out said that nasal sprays would not work, I just wanted to demonstrate (which I think I did thoroughly enough) that was a fallacious claim.

You are 100% correct & I said thank you for pointing out that it CAN be done. That is great honestly. You can understand why my views are a tad different than the average person though because I'm very used to it being done IM/IV 100% of the time. That is what you are taught to do in the ER, that is what you are taught in school, & that is what I was taught when I was an EMT & how we had always done it.

For me I can't justify using a vial meant for IM/IV on someone OD'ing any other way than it was intended to be used & that I was taught to use it. That would be IM on anyone OD'ing in my house. I can't be confident in my work as a professional if I try to give it to someone nasally. Also I have no idea what they are using to dispense this nasally & how I'm dosing someone. It seems to be overlooked as well that it isn't the Naloxone overdose im concerned of. It's the underdose I'm concerned about & wasting precious time when someone isn't breathing. I know exactly how much Naloxone to give someone in one dose IM to counteract an OD, when using nasal spray I might have to redose a few times trying to get it right because I wouldn't know how much they had actually absorbed yet or not.

I'm glad you can see why for me I just can't justify not using my training and what I know when someone is in a bad spot and overdosed & that would be an IM dose I could accurately measure out in a quick efficient manner. During OD's it's all about time and being quick to avoid brain damage when someone stops breathing.

I'm 100% with you on saying I'd rather have it nasally than not at all while waiting for the EMT's also I think if it's effective like you have shown it is I'd LOVE it if the NPE's did a class & issued nasal spray dosers of Naloxone to people who complete a class. I'd much rather they certify someone with no training on IV/IM injections on how to use a nasal spray to give someone Naloxone than give them vials of naloxone and tell them to IV/IM it to people. Although I think it would be perfectly fine to give a class through the NEP's on how to IM it as well. As I think anyone can learn how to properly IM & what is safe and what is not in a relatively short period of time. If they have proved the nasal route is as effective though and could be used while waiting for the EMT's I would rather have them go this route with releasing Naloxone to the public.

What I'd like more than anything is if these classes also gave them a course in taking care of the patient/person after the Naloxone was administered and while the EMT's were coming as well as giving basic CPR classes to get people breathing again. Make it an even 2 hour class and give out the Naloxone and a certificate at the end. Crap I'd even volunteer to teach the class in my local area.

Also I wasn't sure if I was supposed to feel bad for swiping a few vials of Narcan from the hospital while I was there cause i certainly don't. I work in an ER and if I was a stupid I could take anything especially some as easy as that but I wouldn't. Never would take anything from work, but while I was a patient there I absolutely did because the nurse was being sloppy and not doing her job. Plus those 3 vials could save 3 lives throughout the time I'm alive & are doing much more good outside the hospital than they were in. Mostly considering the fact they were issuing them, charging me for them, & when going un-used they were "wasting" them out as we say in the hospital meaning they were dumping them down the sink because I payed for them and didn't need them. Since they were already dispensed and payed for they waste them when not being used. So they were going down the drain or in my pocket.

Where are they already issuing these spray, my whole basis for my stance was the idea of making my own home brew nasal spray like suggested out of the IM/IV vials which is why I was so worried about dosage & how evenly the dosing would be. If it was a meant to spray proper dosing nasal spray package of Narcan like you are suggesting now that I'm reading closer I'm all for that as it is medically meant for nasal dosing & obviously has to have some kind of method of proper dosing. That's much different then the original statement I responded to where it said to make my own home brew nasal spray out of the vials from the hospital mean to be injected. I just don't know how I could feel comfortable making my own nasal spray & being confident in it during an OD.

You OD at my house your getting the needle buddy :-D

i think it should also be said that its damn near impossible (like 200 times the average dose) to OD on naloxone so i really don't think you need to be precise, just give a lot for good measure.

The problem is I'm not worried about an OD as I already know that isn't likely to do anything unless the dose is heroic. it's the time wasted under dosing a few times & trying to re-dose and wait until I've finally hit the spot I neede to be. I can accurately KNOW I'm at a good common dose with a syringe and doing it IM like I was taught in the hospital setting.

It'[s a great idea it just would have to be proven to me how to accurately dose. Just read the paragraph above me to Cane2 to see my stance on the situation. The nasal spray is great and if that effective like it seems to be it could be a totally great tool for the public. Id even teach the classes to certify people if i could in my area.
 
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For me I can't justify using a vial meant for IM/IV on someone OD'ing any other way than it was intended to be used & that I was taught to use it. That would be IM on anyone OD'ing in my house. I can't be confident in my work as a professional if I try to give it to someone nasally.

I'm glad you can see why for me I just can't justify not using my training and what I know when someone is in a bad spot and overdosed & that would be an IM dose I could accurately measure out in a quick efficient manner. During OD's it's all about time and being quick to avoid brain damage when someone stops breathing.


This makes perfect sense, I think we both share the same common goal and if I had your training and experience, I would feel more comfortable if I had vials and syringes in cause of emergency.

...Although I think it would be perfectly fine to give a class through the NEP's on how to IM it as well. As I think anyone can learn how to properly IM & what is safe and what is not in a relatively short period of time. If they have proved the nasal route is as effective though and could be used while waiting for the EMT's I would rather have them go this route with releasing Naloxone to the public.

What I'd like more than anything is if these classes also gave them a course in taking care of the patient/person after the Naloxone was administered and while the EMT's were coming as well as giving basic CPR classes to get people breathing again. Make it an even 2 hour class and give out the Naloxone and a certificate at the end. Crap I'd even volunteer to teach the class in my local area.

That's a great idea, in the interest of harm reduction I'd love to see people learn more about what to do in this situation so we have less ice baths and jamming stimulants in people's noses and shit like that. Maybe its my idealism but I'd like to think that since people ARE throwing people in ice water and doing measures like this that they want to help and hopefully they would be willing to take a brief class to ensure other people's safety.

Also I wasn't sure if I was supposed to feel bad for swiping a few vials of Narcan from the hospital while I was there cause i certainly don't.

I definitely don't think you should feel bad, I know I wouldn't. It absolutely could be a matter of life or death (yours or someone else's) and so I definitely think it was a worthwhile decision.

Where are they already issuing these spray, my whole basis for my stance was the idea of making my own home brew nasal spray like suggested out of the IM/IV vials which is why I was so worried about dosage & how evenly the dosing would be. If it was a meant to spray proper dosing nasal spray package of Narcan like you are suggesting now that I'm reading closer I'm all for that as it is medically meant for nasal dosing & obviously has to have some kind of method of proper dosing. That's much different then the original statement I responded to where it said to make my own home brew nasal spray out of the vials from the hospital mean to be injected. I just don't know how I could feel comfortable making my own nasal spray & being confident in it during an OD.

You OD at my house your getting the needle buddy :-D

I completely agree with your stance on the homemade nasal spray and sorry I mistook your response to that. In your situation I definitely wouldn't try to make a nasal spray myself instead of using a tried and true method. If I OD'd in your company, it is reassuring that you know what to do and have the resources to do it.

My main argument was that the intranasal MOA is a viable option and through the way it was done in Boston, could be very useful and save lives.
 
i think it should also be said that its damn near impossible (like 200 times the average dose) to OD on naloxone so i really don't think you need to be precise, just give a lot for good measure.

If you're IMing naloxone, you want to give a known amount; IMing a lot of liquid quickly is rather painful.

Can Narcan be ordered online from a country where it is OTC?

It "could" be, but whether it'll actually get to you or not, or if the supplier is even legitimate, is a different story all together.

US law should change so that Narcan can be acquired by adults OTC as a means to prevent death.
 
Isn't it a god damned shame that the government would rather see people die, than be called "soft on drugs" by adopting a harm reduction strategy. I know here in the Great White North, safe injection sites are just now being accepted, (in Vancouver as far as I know), after proving that they save lives. To tell the truth, I'm just way too scared of IV opiates to actually do them, but I think it's morally wrong to withhold potential life saving because the act of using is illegal. My 2 cents

Kali
 
Isn't it a god damned shame that the government would rather see people die, than be called "soft on drugs" by adopting a harm reduction strategy. I know here in the Great White North, safe injection sites are just now being accepted, (in Vancouver as far as I know), after proving that they save lives. To tell the truth, I'm just way too scared of IV opiates to actually do them, but I think it's morally wrong to withhold potential life saving because the act of using is illegal. My 2 cents

Kali


What else would you expect from the government?
 
Wow this has actually been bugging me all day & I half way want to start a petition in my area and contact the closet exchange and figure out what we could do about this. It should NOT be a big deal to issue Naloxone to the public if It's available like Cane2theLeft is speaking of. Properly dosed made to be used that route nasal spray.

I would gladly volunteer one day a week to teach a class for 1 hour on using the spray & proper care of a person after the Naloxone is administered and you are waiting for the EMT's. I would do this 100% for free if they could implement a program to get these nasal spray Naloxone bottles available to the public. If they were able to do it in Boston they obviously got the government/state to approve of letting them do it. It's shown to be successful and save lives.

I doubt I'll get anywhere with it but I've been so proactive lately & volunteered much of my time lately to helping opiate addicts that I would like to keep doing so. Where I live in Idaho we barely got Methadone approved as an Opioid treatment 13 months ago. That is how far behind this ridiculous state is. They didn't even have a methadone treatment center until 13 months ago! & there is still only 2 in the state. I've actually been doing volunteer work for the local clinic though as I like to work with addicts, especially opiate addicts, and give them my compassion since the rest of the world treats them like scum.

Im a chronic pain patient and former IV heroin addict & I have a great and fulfilling life but I went through hell. Since getting better and still having my life in tact I feel it's my obligation to pay it forward because if it wasn't for a few key people in my life I'd probably been dead long ago. I'm going to see what I would have to do to make this a reality. I just feel if I still lived in southern california this would be an easier reality to convince them into implementing. Up here they didn't even like the idea of methadone up until recent changes & Idaho finally realizing they have a big prescription pill abuse problem.
 
Good man. Stick with it. Also, it cant hurt to write your representatives, but you will probably have more luck on the local level first. It should at least be easy to get by prescription no questions asked for the sake of harm reduction.
 
I hear that Naltrexone is OTC in India, so you can order it from them in pill form without a prescription. A little more work than getting it from the drug store, and more costly, but doable without a prescription.

The only problem is how would you administer it if the person is already knocked out?


Also, is there anything that can more gently reduce a opiate high if you are just a little too high for your comfort but not totally overdosing? If you want to come down just a little bit or perk yourself up, but you are not in the midst of respiratory depression but are about to fall asleep?
 
Call 911- really- you need a paramedic...if you're waiting you can rescue breathe for them...their heart is probably fine, they have just gone into respiratory arrest. If you can manage to get narcan it would be good to have a vial laying around...only problem is sometimes you need alot of it to bring someone around or even get them breathing again. I worked for 7 years in Brooklyn as a medic; some of the fentanyl laced dope had me giving people 10mg just to get them to take a few agonal respirations! Other than that put them in the rescue position- laying on their left side so if they vomit they don't aspirate.
 
I mentioned in the OP that this is no replacement for calling 9-11.

However, a medic is not always around. You could be at a hippie festival in a remote area, camping, or maybe in the middle of a disaster zone like hurricane katrina and you overdosed on pain medication because of an injury. Sometimes its good to have something NOW even if its more ideal to be in the hospital.
 
I've had to use suboxone one time to save my friends life. Im pretty sure he would of been in serious trouble if I hadn't done what I did. Right after admin of the suboxone (like 2mins) he came back too and was like "Dude why am I not high anymore." .. I was just like "man you don't realize what I (AND YOU) just went threw!"

anyways I DON'T recommend dealing with OD's with suboxone but I really had no choice in the situation I was in.. And it did work, thank god.
 
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I got my ass handed to me for saying this a few days ago, but if you want, go look at my post called" life saving milk". Ppl thought I was a troll, and get being an asshole, lying trying to kill ppl or something, but it's the absolute truth. I'm afraid to say anything more than that...Just friendly advice that you're free to take or leave.
 
Also, once when I personally OD'd a friend put a couple 8mg suboxone under my tounge. i was sick as shit for like 30 something hours, but i woke up...
 
Can methadone or suboxone clinics prescribe naloxone or naltrexone as they do the maintenance drugs?

I dont know how expensive it is, but I think it should be available OTC within the confines of a needle exchange or maintenance/WD clinic. I sometimes feel that the government's recent ban-lift on needle exchange programs here in the US was more about pleasing health policy advocates who were/are vocal about the reality of transmitting HIV via shared needles, rather than based on a genuine concern for the actual lives of IV drug users in general. Kinda makes me sick.

Also I was surprised to hear someone else mention not to worry about police involvement if you need to call the paramedics... when I OD'd and the medics were called in, four cops showed up as well and tried grilling me about where I got it. I wasn't even fully conscious at the time and had just had a grand mal seizure from the epinephrine (adrenaline) shot I had to have in lieu of the 3-4 failed narcan shots the paramedics had tried to bring me back with initially. This was just outside of Philadelphia, PA, too, so I don't think it's restricted to just Texas!!

~ vaya
 
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