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Opioids opiate irritability

I know how you feel, Pillthrill, but honestly,when I think about it, when I withdrawal from opiates, all those annoyances don't even comapare to when I feel opiated. Also, weed doesn't help you? Weed with opiates or benzos usually make me into the nicest guy in the world. That's only if it's mixed in with stronger narcotics though.
 
haha aint that crazy you takin the pills to get high then you end up pissed off lol i always honk at ppl and drive like an asshole then later im like wow i was actin crazy
 
Typically I am a calm person, but in my dope shooting days a lot of times I would get VERY fucking angry, randomly. Not at a person in particular usually, but just in general. I have always been an anxious person, but never angry up until recently. 2009 was a fucking shit-ass year (my dad died, I got diagnosed with cancer, financial shit, legal trouble, lost my girlfriend of over three years) so I think I haven't properly dealt with many of these issues and i have a lot of stored up anger that sometimes just overflows and i'll explode. Ever since I got onto MMT though, my emotions and anxiety seem to be contained much better. Still not close to perfect, but much much better.
 
Ya, it's wierd.. i noticed that too, though i thought it was just me..
Everytime i'd go out for a smoke after using and have to shuffle when i get outside because the alley was covered in ice.. and i would get fucking furious over it!
i hated having to walk slowly so i don't slip on that asshole ice.. i had the thought in my head "where the fuck does that ice get off being slippery" and i would be blinded by a seething rage caused by something as trivial and arbitrary as having to walk on ice that would always kill my high.. which got me even more irritable..
 
This is all very interesting... So, it's a pretty common effect, here on BL..

Anyone ever heard of "Disinhibition"? Basically, it's when something or other (a drug, in this case) causes the person's normal anger-inhibition (that biochemical thing that stops most of us from acting out our insane, angry thoughts on others when we're even slightly upset) to be suppressed. Benzos are renowned Disinhibitors of this type. I've personally gone absolutely fucking crazy while on medium doses of Ativan, Xanax, or even Klonopin - the effects would get crazier when mixed with opiates..

Got myself and my band banned from the city of Santa Monica, thanks to my inciting a destructive 4-person riot (the band, that is heh) that pissed the locals off. That night it was Klonopin and Oxy. I don't blame them, though - we grabbed handsaws and other tools and began dismantling parts of the club we'd just played at hahaha Cops came, cuffed us, told us never to come back to their "town". Hilarious!
Also, during one insane night on Ativan+Norco, some self-righteous, stuck up weed dealer refused to come downstairs to his neighbors pad (his neighbor=my friend) to sell us some weed. It was a trip down a few stairs, not stairwells. So after my friend talked shit to his lazy ass on the phone, he came downstairs, with a knife, opened the door and stepped in - I was quite pissed about his retarded behavior, and totally "Disinhibited" so before he even said a word, I stood up from the couch and ran at him, tackled him, took the knife by twisting his wrist, then held him in a rear naked choke for a min, while yelling weird shit that just...came to mind hahaha

Ahhh Benzopiate Nights.... glad I remember them.
 
This actually happened to me tonight, for about an hour I was mr chill, actually having a really pleasant series of conversations with the flatmate I usually just avoid talking to since we have nothing in common (He's straight edge for a start lol) and then with the codeine in full swing and me feeling more relaxed than ever some BS comes up on the news and I suddenly launch into a super rant.

I really do think as Breathe said its just a cause of disinhibition, usually Im Mr Nice Guy but I guess opiates just stop that signal.
 
hahah, i thought everybody got like that... I always do. Especially if someone asks a stupid ass question. Those of you who said you dont get irritable, i wanna get high with yall..all the kids I used to use with acted like fools...including myself. :)
 
Well if we're talking only opiates, then it's purely an irritability thing - and I've noticed that it has completely to do with the rather delicate state of mind that is induced by them. You see, most of us are social animals.. We act and react to others in our presence, and when we're feeling better than usual, we react with more intensity.
I've noticed that no matter what the strength of opiate, whether in my Norco days, or the H. days, if someone - ANYONE - does or says something that twists my delicate opiated mindset towards the negative, I feel the pangs of adrenaline and anger rising instantly. Suddenly, the mild, chill headspace I inhabited has become way too active and way too negative in a manner of speaking, and it's almost as if the drug loses its mind-stabilization effects right at that moment. That would be enough to piss anyone off!

I've also noticed that this tends to happen more with a longer duration of use, as well as an inclination to be more and more "delicate" in mindset as the drug wears on. The very first rush is seemingly immune, but the come up, plateau, and come down are all susceptible to this irritability, it seems. One theory I have is that since this seems to get worse the more a person uses, it must be an unfulfilled wish, or unconscious expectation that we will always always always get that super-awesome high that we love; the one that kept us coming back for more - and with more use, it's quite unlikely that we can feel that way, until we stop or cut back and increase again. Like the drug is screwing us over, lying - telling us "sure, you'll feel great!" then we do it and.....not bad...not great....just bleh....

Fuck, I'm glad I'm not there right now hahah
 
I read something about how the increase in endorphins lowers levels of serotonin...

Which in turn would make you more annoyed and irritable.

Not really sure about that though, it was something like that.
 
oh man, happy to have found this.

i used to call my boyfriend jekyll and hyde, we did lots of painkillers together and i would float away, happy as a clam and he would immediately after the sniff, turn into the monster. "stop walking like that its so annoying" "where are my cigarettes, find them, dont just stand there!!!" "i dont want you to be here anymore, go home" "you need to learn to stop being a bitch" "you smoke blunts like an idiot" LOL he was pathetic, on and on and on and on.

he would only call me a bitch when high, he would ONLY complain about "things i do" that are "so fucking annoying" when he was high. im not saying i never annoyed him otherwise, but when sober we were blissfully happy with each other. i never understood it, i almost couldnt get mad at anyone when i was high. the best part is he would then later deny the things he said bc he always more or less forgot everything if he was high all night.

it ruined our relationship, once the drugs were removed i couldnt forget the events that he set in motion due to "opiate rage". i did however, think it was just him. i never saw it in anyone else. and it was just like clockwork. i could tell over the phone if he was high and lying to me bc he would get mad at the LENGTH OF MY SENTENCES. seriously crazy shit. i definetely felt like it was a result of the comedown/not being as high as he wanted to be. it happened a lot more when we couldnt get a lot of stuff, lets say half of his normal desired dose - the rage would be worse.

someone said its the interruption of the euphoria - although i dont experience it, thats precisely what i think it is.
 
I've experienced this from opiates/opioids since the beginning. For me, it's the worst when using oxycodone, hydrocodone and morphine. The only exception IME has been oxymorphone (Nubain) which, considering the list of opiates that causes irritability, makes little sense to me!

Unfortunately I do not have the answer as to *why* this happens, but it makes for a really interesting area of future research and exploration. Perhaps if we knew what neurophysiological mechanisms were at play in opiate-induced aggression, we would be able to construct ways of preventing it...

~ vaya
 
It was SO bad the other night! I was aware that EVERYTHING that came out of my mouth was bitch. I was annoyed at my own internal voice in my head!!
My bf mentioned it and I was like "Yeah, I knew it and I was trying not to let start a fight or anything." He just laughed and said there was nothing to even fight ABOUT but I was kinda being bitchy.
Well at least I got someone that will put up with me. :D
 
I have sometimes noticed this - although on average i probably have a higher irritability threshold when on opiates (i *most of the time* find i get less mad than if sober and in the same situation).

But i have been pretty irritated before; after dosing a maintenance amount of drug.

Could it be that the times when you are irritated you aren't actually very high? Like could you be actually suffering an overall lack of endorphins cos your body needs a larger dose?

Or do you guys get irritated even when high as fuck?

Interesting stuff anyway.
 
Maybe it's the H altering brain chemistry so it's unbalanced .
I get it with MOST drugs. Even weed lol.

But I found taking a week-month break (depending on how heavy you use) then the irratibility goes wayyyy down .

I know the break thing is hard for H users though eh ?
 
when i take tramadol i get so pissed off at little things like i was freaking on my sister the one day cause she annoyed me once and i hated her for like the rest of the day its was fuckin weird tramadol is a weird drug.
 
I usually take a little bit of clonazepam at the first sign of irritability. I generally am more likely to get irritable if I've been doing opiates daily/almost daily.
 
it depends what kind of mood i'm in. i find it best to try and remain in a calmed state, and i can usually avoid the rage. sometimes tho if someone snaps at me, i might get kind of testy. if i dont achieve the high i was aiming for then i get it as well.
 
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