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nurofen plus-bullshit?

the nurofen + caplets have a protective outer coating which can be peeled off with some patience. Once this is done, inspect the caplets carefully and you will see that there are indeed two seperate halves (look very closely under the right light and you will see a seam), one codeine, the other ibu.

This should be all the confirmation you require. I also doubt a pharmacist will have the answers for you.
 
Interesting thread. After reading my associate and I decided to do some testing on the two separated halves (separated as per previous instructions). In a solution of sodium hydroxide, we placed the first half marked with the "N+", and in another container of sodium hydroxide solution of equal concentration, the other unmarked half of the pill.

The results were noticeably different (see pics) where the N+ side dissolved at a fairly quick pace, leaving only the coating of the pill intact, whereas the unmarked side did not dissolve at all. This obviously suggests that the pills contents are separated.

I would have thought the results would be the other way around, as codeine is a base as mentioned before and shouldn't react with a strong base like NaOH, and ibuprofen being acidic should be more reactive than codeine with NaOH.

Perhaps it is something to do with the binder/filler for each half? Not sure. Anyone else's feedback on the matter would be appreciated.
 

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Follow up...

Tried 8 of the "N+" halves, equalling 102.4 mg of codeine (it's been quite a while since I've had my hands on a sizable quantity of unadultered codeine), quite nice.

Seemed to be a while before peak effects were noticed (halves were swallowed whole), perhaps one should try crush them up, or extract the codeine using the cold water extraction technique etc...

I'd just like to thank the makers of nurofen plus for making my weekend that little bit better :)
 
particle said:

The results were noticeably different (see pics) where the N+ side dissolved at a fairly quick pace, leaving only the coating of the pill intact, whereas the unmarked side did not dissolve at all. This obviously suggests that the pills contents are separated.

I would have thought the results would be the other way around, as codeine is a base as mentioned before and shouldn't react with a strong base like NaOH, and ibuprofen being acidic should be more reactive than codeine with NA0H
Click to expand...

Perhaps if the Ibu was directly correlated in acidity as the NAOH was basic then i would assume that these would cancel out and have no reaction, but if the Codeine was at a more neutral basic level than the NAOH then it would be broken down by the stronger base right?
 
^^

Other way around mate... the acidic ibuprofen will react with the basic NaOH to form a salt which will be soluble in water. The basic (or in this case neutral) codeine will not react (or react very weakly) and therefore remain undamaged.

good job particle... also, how concentrated was the NaOH soln?
 
^^^^ I was about to say that.... It wouldve been weird if the codiene reacted.. Opposites attract in chemistry, remember?


I think we need more greenlighters like particle here!
 
N plus

What are the ramifications of mixing a large quantity of codein taken from say a N plus pill, with other substances such as alcohol.

Also what effects can someone expect from your average codein trip. say 100 - 200 mg dose.

i have been recently been taking Nurofen Plus quite regulary for back pain and a knee problem, the chemist then told me that prolonged usage will lead to a stomach ulcer, not a nice thought so i have decided tonight with a particulary sore back to split hem up and take 115 mg of codein <screw you back Ha! Ha!>

and yes im sqedualled in tomorow to see the old croaker to get something appropriat so no gibs please.

bah iv gone totoally off the subject.
 
100~200mg depending on your tolerance might do anything from nothing to put you in a very happy relaxed mood, content to just lie there letting your thoughts swirl. Thats what 300mg does to me.

I just read the bit of paper that comes with a Nurofen Plus packet and it sdays that you can buy them in packs opf 72!! Is that perscription only or are they about somewhere OTC? Largest I've seen OTC is 24.
 
Me again...

Cheers for the feedback peeps, it was a pleasure to provide some (perhaps) useful info. :)

It's been a couple of months since our little experiment, so the exact concentration of the NaOH solution escapes me at the moment (although from what I can remember, it was was of quite a high concentration).

I've also had time to play around with the dosage etc, and it's pretty clear cut that these little white pills have some very nice effects.

Peace! =D
 
Last edited:
AlphaNumeric said:
100~200mg depending on your tolerance might do anything from nothing to put you in a very happy relaxed mood, content to just lie there letting your thoughts swirl. Thats what 300mg does to me.

I just read the bit of paper that comes with a Nurofen Plus packet and it sdays that you can buy them in packs opf 72!! Is that perscription only or are they about somewhere OTC? Largest I've seen OTC is 24.
Click to expand...

i bought a pack of 48 on the weekend from the local store. i have already split them (i was suprised on how easy they come apart and you can see the split perfectly alone a convexed line, ive also crushed all 48 of them and was going to put some in a class of water and let it desolve and drink. going to take about 150mg's tonight. see what happenes :D ive never had an opiate before)
 
Extract the codeine

Going off memory now, but it goes something like...

Using Nurofen Plus tablets containing 12.8mg of Codeine:-
-Prepare an ice bath
-Crush pills into a reasonably fine powder
-Pour powder into a glass of very warm to hot glass of water
-Stir
-Allow to sit for 5 minutes
-Put this glass of warm water with your pill mass into your ice bath
-Make sure the level of water in the bath just exceeds that of the level of water in your glass
-Allow this to sit until the water in the glass falls to the temperature of that in the ice bath
-Give it 10 minutes. During this time prepare your filter
-For your filter you will need one or two cotton balls fitting nicely (but not too tightly) into the neck. Above that two coffee filters.
-When you are ready pour the contents of your (now cold glass of water with pill mass) into the filters and allow your goodies (codeine free of Ibuprofen) drip into your collection glass.
-Drink it. And remember the taste. It's very bitter, but the sensation of this opiate coming over you is quite pleasant.
 
Re: Extract the codeine

Kaister said:
Going off memory now, but it goes something like...

Using Nurofen Plus tablets containing 12.8mg of Codeine:-
-Prepare an ice bath
-Crush pills into a reasonably fine powder
-Pour powder into a glass of very warm to hot glass of water
-Stir
-Allow to sit for 5 minutes
-Put this glass of warm water with your pill mass into your ice bath
-Make sure the level of water in the bath just exceeds that of the level of water in your glass
-Allow this to sit until the water in the glass falls to the temperature of that in the ice bath
-Give it 10 minutes. During this time prepare your filter
-For your filter you will need one or two cotton balls fitting nicely (but not too tightly) into the neck. Above that two coffee filters.
-When you are ready pour the contents of your (now cold glass of water with pill mass) into the filters and allow your goodies (codeine free of Ibuprofen) drip into your collection glass.
-Drink it. And remember the taste. It's very bitter, but the sensation of this opiate coming over you is quite pleasant.
Click to expand...

Instead of doing that, why not just cut them in half and swallow the Codeine side? :\
Less of an arse about!
Also maybe throw some Grapefruit juice into the equation!;)
 
Gaz_hmmmm,
The debate's been going on too long. Call it paranoia, but I'm not convinced that pharmaceutical companies would make it that easy, especially knowing what they're capable of.
Knowing the solubility of that product you desire under certain conditions makes extracting it (or a good percentage) safer.
 
Further to that...

You're somewhat right, but at the end of the day extracting it using that technique *is* a pain in the ass, also, I'm sure a few milligrams of trace ibuprofen ain't gonna do anyone any harm - if anything it's probably a good thing for any headaches which might ensue :)

You should worry more if these were pills containing paracetamol, as that's not very friendly to your liver on repeated/large doses.

I've tried eating these halves on many occaissions, they work fine - there would be no other feasable reason for the makers of nurofen plus to go to the lengths of pressing two seperate halves of the pill, using two different kind of binders and fillers (easily noticable by the slightly more beige tone to the N + side) then putting the two together other than the alter the absorption rate of either active ingredient or because of some limitation to the manufacturing process and having these two substances together.

That's my opinion anyway =D
 
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