I checked this out and grapefruit juice can affect the enzyme CYP3A4 and increase the bioavailability of certain drugs. From what I read it only affects the ORAL availability of these drugs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1873672/
Yes, there was another thread about this http://www.bluelight.org/vb/threads/771436-Homemade-u-47700-nasal-spraySo is 100mg of U-47700 able to dissolve in 10ml of warm water?
Yes, there was another thread about this http://www.bluelight.org/vb/threads/771436-Homemade-u-47700-nasal-spray
BACKROUND : I just picked up some of this fun chem. I was on a 4 month break from using 120 Morphine ER twice a week, so I have low tolerance to opiates.
REVIEW : It arrived from my vendor after about 8 days from being shipped, I was very excited to try this as I heard it was extremely euphoric. Upon opening the bag, I noticed the powder was a clean white color with no large chunks. This made me happy as I heard some vendors having shitty yellow caustic batches. Last night I snorted about ~10mg at 7:00, and felt the clean pronounced feeling of opiates start rushing through my body and limbs after around 15 minutes. This warm euphoria lasted about an hour before it wore off into a nice buzz, which also lasted about an hour before wearing off mostly. I slept around 9 and woke up at 12, then tried to sleep, only to wake up at 3 and wait until I went to school. I'm not sure why I woke up at odd times and was restless, but it wasn't unbearable. A good chem. 8/10
A little update on this stuff, tolerance rises pretty fast but you can keep it low and consistent if you have good control. (not saying to do it though, we never know what could happen. addiction is always a possibility.) After 4 days or scattered usage, I'm on about ~15-20mg to feel pretty awesome. To my surprise, my nose is not as fucked as I anticipated. I can breathe just fine but have a runny nose occasionally, but this could be allergies. Def ordering more for me and some friends![]()
Yes you did, thanks!Oh sorry, I must have misunderstood! My morphine doses were 120mg all at once plugged. If I had to guestimate I would say 25mg of U-4 intranasally feels about the same as my 120mg morphine dose. Hope I answered your question!