Far from the perfect opioid, its quite caustic and hard on the nose!
My experience with it is limited to oral as I also snorted about 10mg in each nostril and blew my nose before I got the drip as I began rethinking it, say about 3-5min after snorting. One notable factor is I am on MMT 170mg/day and I had taken 400mg methadone approximately when I decided to stop for 2 days to see how it felt. I didn't take any opioids the next day, going to bed at night I was thinking of taking some and eventually did take 10mg orally in a capsule due to the caustic nature, as an allergy test to be more at ease when the right time came. I would say 36-48hrs after my double dose, I began to use it strictly orally as I didn't want to fuck my body up like the notorious article on erowid where a group of chemistry students made a Demerol derivative or like the Krokodil horror stories, where people destroy their bodies in search for an opioid high. I began using on the mentality that if an opioid is pure without APAP or toxic binders, it doesn't harm any organs and its only downside being highly addictive. MT-45 was also quite sketchy also so you can understand my skepticism with this chemical. I decided that orally, capsuled, would be the only sensible way to consume this, as I have a phobia of needles.
After 36-48hrs I found 30mg+ doses necessary to get anything. I went for about 60hrs without methadone at the most, during which time I had used about 200mg, orally. During the entire time, even with smaller doses, much like Hamilton said I felt it going up but beside that it leveled off much like hydromorphone would, which I also didn't find very special or up high my preference list, though for someone that likes hydromorphone its should be interesting to hear their opinions. I will say one thing, while it wasn't something that broke through my dose not much will, even fentanyl wouldn't break through after 80mg. I didn't feel euphoric but I felt the drug and didn't get any sickness, was able to appreciate the legs, it has a long duration of 5+hrs orally and takes effect within 15-20min. The only time I felt somewhat euphoric was after I took 1mg lorazepam, that made me very sedated and I eventually went to sleep. In the morning while reading the reports of people's hearts stopping on this mix of benzos on top, I began to think they weren't trolls at all since my tolerance to benzos is such that 4mg clonazepam and 400mg methadone is ok, though could use 3x to get *fucked*. I needed about 60mg and then another 30mg orally after half hour from the 60mg, taken with the 1mg lorazepam. I only had slightly more than 1 full day to use this.
In conclusion, it really would be a perfect opioid or at least on par with hydromorphone if and only if it wasn't caustic...that we know about there may be lots of other side effects beside this that we haven't heard of yet. Right now the one guy has it for a very high price, think 400/g in which case, at least at this point knowing the little we know, its far from ideal. Even though I blew my nose before the drips the next day my nose was very hurt, bloody with a thick case of scabbing.....in other words a lot of damage from 1 single use.