MXE on the comedown of MDMA is wonderful and should be enjoyed by everyone (IMHO).
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yeah definitely second that one. i find mxe to be the perfect antidote to almost any drug on the fade out/ come down.
Mixing the two together though is a potentially very dangerous thing to do. i know this from past experience. Like with anything it depends on tolerance so its hard to give numbers. If you have next to no tolerance to mxe, so that around 40 mg up the nose gives you a fairly strong buzz then I would suggest exercising extreme caution in combing mdma with mxe. I've done it, and at varying levels of tolerance, with drastically different outcomes being the outcome.
Example one - this is acid not mdma, but I've combined mxe with just about every stim you can think of so hopefully this example has some merit.
I had no mxe tolerance at the time and had tried it maybe 3 or 4 times previously. I combined just 40mg mxe with half a cube of very good quality acid and I was so loaded I really felt on the verge of hospitalisation.
Example two - I had been using mxe for well over a year and had a sky high tolerance. This example event happened within 2 weeks of the uk ban in fact. I bumped 250 mg of Mxe while peaking on a full cube of the same acid in the first example and was fine. I actually did this in a club down on brighton sea front.
I hope that serves as some sort of guide, its one of the few instances where i can give numbers. Seriously though, mxe and stim combo's have real potentials for disaster. I can remember atleast 4 or 5 incidents where i combined mxe with a stim (mdai and 6 apb were amongst the substances on my list) and had shooting pains down my left arm and felt my heart beating so hard I thought I might not make it.
My advice would be to snort the mxe, so as to get a nice rapid onset - no nasty surprises down the line from oral doses that haven't fullly hit yet, and work your way up. There is no harm in doing a 20mg bump and waiting 15 mins before doning another one. You can always take more but you can't ever turn the clock back.