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Most physically-changing drug.

hexxx said:
Thanks for the clarification, that's what I figured. Now I need to find the dumbest drug rumors thread and post - if it isn't already there.

Are any drugs given to combat the vaso-constrictive properties of coke? Any at all as a preventative treatment? The only vaso-dilators I can think of is weed and salbutamol. Both are probable worse for someone who is uncomfortable from too much coke. They will potentiate the effects due to their stimulant nature..
Would alpha or calcium blockers help - or is this potentially very dangerous. Could they prevent a stroke?
ACE inhibitors? They seem to have potential but I'm not doctor.
I know Beta blockers aren't recommended at all, people get flamed for recommending them so I won't go there.

I am not recommending you take any of the above drugs to prevent vasoconstriction.
But having a possible antidote on hand might be a good idea. in the name of harm prevention if one exists.

Thanks again, and sorry for the slightly OT - but we are talking bout possible prevention of heart damage by coke.
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there are many cardiac variables that have been shown in animal studies but those same variables haven't been easily or predictably reproduced in human studies. of course in an ER situation you're rarely, if ever, dealing with pure cocaine so whatever other substances that could be in the coke, like meth, also contribute to cardiac symptoms and damage. at best the cardiac output is certainly going to be less and blood pressures will be increased which both affect the brain and other organs. i personally don't know of an "antidote" for coke ODs that works similar to narcan (naloxene) in opiate ODs although i'm not trying to say none exists; i don't know of any in common use in ER situations. i doubt calcium channel blockers or ACE inhibitors would help a hell of a lot especially when someone is in a crash situation but i'm not a doc either, just a lowly RN ;) so i wouldn't swear on my license that they absolutely won't help but i doubt it. i doubt they would help much with cocaine induced strokes either.

interesting questions hexxx, but the only certain way to avoid bleeds or cardiac damage from cocaine is to not consume any cocaine at all.
 
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I dont see why people need meth an heroin, ok lemme explain u have morphine and adderall or dexes or whatever , do u really need to get a little bit higher at that huge of a cost ? I dunno im never doing meth or heroin those are the two soul ruiners both arent even natural. Were coke i think shuld be legal just becuz its fun at partys but after ur just likee ughh
 
I dont know if anyone has mentioned cigarettes? It may time its time on some people and for some reason its a lot more noticeable on women but people who smoke in their 40's, 50' and 60's can be instantly identified as smokers if theyve been going for long enough, it looks really bad. I often look at older women who look like shit and wonder to myself if they are either alcoholics, junkies or simply big smokers and id say usually they are big smokers.

Ive known people who've IV'd heroin/meth(most often not daily though) for years and as long as they arent completely off the planet then they wouldnt even look like drugs users, of course I know of people whove been injecting ice for a year and they look like anorexic, sick junkies(in the true sense) and heroin addicts who look pale and sad and really just weird.

I was injecting ritalin, oxycontin, heroin, MS-Contin, Methamphetamine(crystal, rock and base) psychs(doesnt matter in this thread)...And in the period I was using all that people could tell as soon as they looked at me that I used IV(and I dont call everyone who uses a needle a junky, you dont have to be an IV user to be a junky) It really saddened me that I had become this bad. but its all in the lifestyle. These people im talking about who bang up and still look healthy is coz they eat and sleep and live like a normal person. Ive had a break for a good 3-5 months clean of meth since 2 nights ago when I IV'd 1/2 a gram on some very clean meth, I looked at myself in the mirror waiting to see that gaunt looking, pimply,oily skin that id normally see after a night of meth...I saw a normal looking me, I didnt look drug fucked at all and I believe that is because ive been living in an extremely healthy manner. Thats how all the men in the gay scene smoke/IV tons, and tons of meth and keep their muscular physique, its all in exercise and eating the right food. I Eat fuckloads of food, but its the right kind of food so im able to keep my weight at what it should be.

Anyway ive gone way too far in this post ut anyway...later peoples.
 
habboz said:
I dont see why people need meth an heroin, ok lemme explain u have morphine and adderall or dexes or whatever , do u really need to get a little bit higher at that huge of a cost ? I dunno im never doing meth or heroin those are the two soul ruiners both arent even natural. Were coke i think shuld be legal just becuz its fun at partys but after ur just likee ughh
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very ignorant post! they do meth or heroin because they like the high the drug gives. the heroin high is better than most pharmaceutical opioids and the methamphetamine high is better than most pharmie amps. Also, pharmie opioids are very expensive, especially oxycontin and opana, its much cheaper to have a heroin habit than most pharmie habits, which is why lots of ppl switch. also, meth is available in a prescription form of "Desoxyn". its not quite the same but it is pure pharmaceutical methamphetamine. Even heroin(diamorphine) is available in prescription form over in Europe for pain.

The whole natural vs. synthetic argument is so stupid. Just because something is natural does not mean its safer. Many poisons are from plants, datura is a plant. Meth is a synthetic drug but heroin is semi-synthetic. The opium from poppies are made into a morphine base and then they acetylize the morphine with acetic anhydride and that is how heroin is made. Cocaine is not anymore natural than heroin, or safer. In fact, cocaine is much more damaging physically than heroin or any opiate. Opiates are very benign on the body.

Last thing, you say you believe cocaine should be legal because its fun at partys but afterwards, "your like ugh"? Well yes cocaine is fun for a very short time and then you have a comedown. Meth is similar, it has a very fun high and lasts a good while and then has a horrible comedown afterwards that makes you not wanna do it, for some people. Heroin is also veryy fun and has no comedown at all really. They all can be equally fun at a party. It just depends on the personal preference of the person. Learn some shit before you make an ignorant post like that again.

P.S. any drug can be a "soul ruiner". It just depends on the person and how much they abuse the drug. I hate how heroin and meth are singled out.
 
If you really wanna get into it after a few chemical changes meth comes from ephedra which is a plant and heroin is from a poppy, just coz coke is natural dont mean shit. Coke is just as dangerous and heroin or meth, if all used in a responsible matter coke is probably more dangerous. Your way more likely to have a heart attack from a normal dose of meth and you can live your whole life injecting heroin with no physical danger if the H was pure and the dose was known(which obviously never happens) but coke is still bad for you too, dont fool yourself.
 
habboz said:
I dont see why people need meth an heroin, ok lemme explain u have morphine and adderall or dexes or whatever , do u really need to get a little bit higher at that huge of a cost ? I dunno im never doing meth or heroin those are the two soul ruiners both arent even natural. Were coke i think shuld be legal just becuz its fun at partys but after ur just likee ughh
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Because adderall is lame? :\

I don't even know how much Adderall I would have to do to get as high as I do on meth. Once you do meth there is no going back, IMO.

But seriously, this way off on a tangent but 'aren't even natural?' does something being natural somehow make it safe? And what drug IS natural anymore? There's no more additives in meth and heroin than any other drug (also, heroin < morphine < opium poppies.) People just love to claim that their drug is OK because it's natural...
 
Crystal meth is the most physically changing drug, it will make you look like a fucked up crackhead monster after a short period of time, also if you try it you will def get really hooked, stay away from meth just do heroin instead. :)
 
meth by far is the most physically changing. heroin changes the soul, makes me feel lost and empty without it, like im searching for something i know i wont find until i do it.
 
chrisinabox said:
very ignorant post! they do meth or heroin because they like the high the drug gives. the heroin high is better than most pharmaceutical opioids and the methamphetamine high is better than most pharmie amps. Also, pharmie opioids are very expensive, especially oxycontin and opana, its much cheaper to have a heroin habit than most pharmie habits, which is why lots of ppl switch. also, meth is available in a prescription form of "Desoxyn". its not quite the same but it is pure pharmaceutical methamphetamine. Even heroin(diamorphine) is available in prescription form over in Europe for pain.

The whole natural vs. synthetic argument is so stupid. Just because something is natural does not mean its safer. Many poisons are from plants, datura is a plant. Meth is a synthetic drug but heroin is semi-synthetic. The opium from poppies are made into a morphine base and then they acetylize the morphine with acetic anhydride and that is how heroin is made. Cocaine is not anymore natural than heroin, or safer. In fact, cocaine is much more damaging physically than heroin or any opiate. Opiates are very benign on the body.

Last thing, you say you believe cocaine should be legal because its fun at partys but afterwards, "your like ugh"? Well yes cocaine is fun for a very short time and then you have a comedown. Meth is similar, it has a very fun high and lasts a good while and then has a horrible comedown afterwards that makes you not wanna do it, for some people. Heroin is also veryy fun and has no comedown at all really. They all can be equally fun at a party. It just depends on the personal preference of the person. Learn some shit before you make an ignorant post like that again.

P.S. any drug can be a "soul ruiner". It just depends on the person and how much they abuse the drug. I hate how heroin and meth are singled out.
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A++ I've tried explaining this to many people but they come back at me with their propaganda they heard somewhere or dismiss it entirely. I wish less people werent so ignorant in the world...

Coke is certainly NOT natural. Have you ever seen videos of coke being made? Gasoline is used in the process! The only thing natural about coke is the coca leaves used to make it.
 
i would say people with crappy MTH. OR benzos, they make me gain weight due to the munchies. Or it could just be a person's overall use of particular drug.
 
Meth argh , yea i don't like singling it out either , i do, just because i hate / love it so much . I don't want to see anyone trying it so i Bash it every chance i get :) . Sorry :( . But meth for sure seems to be the most physically changing honestly. Speed in general "can be" just as changing, but meth has a much longer half life in the body increasing the chances of these things happening a lot more . Even living in a normal environment with funds for your addiction, your chances of a flipping in your image are quite high and very noticable. Very destructive "genetics" meth has
 
Opiates are where it's at <3. I feel overall more in touch with myself /peace with the world. haha. and i don;t have to worry about combating all the bullshit speed brings , i can RELAX and enjoy life
 
okterrific said:
Crystal meth is the most physically changing drug, it will make you look like a fucked up crackhead monster after a short period of time, also if you try it you will def get really hooked, stay away from meth just do heroin instead. :)
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When I was going to college in the 80s there was a lot of meth floating around: a fair bit of it found its way up my nose. I never got addicted to the stuff, and neither did most of my friends save for a couple who started overusing it. OTOH, I got in serious trouble with alcohol and was only able to get control of my booze habit by abstaining altogether.

I wouldn't encourage anyone to experiment with crystal meth: the cost of addiction is far higher than any possible benefits you can get from recreational usage, so the risk outweighs the reward. But I'd also say that most people who tried meth wouldn't enjoy it very much -- "I'm sweaty, twitchy, paranoid and my heart is racing. Where do I get more of this stuff?" Of the rest, most will be able to use it recreationally and a few are going to get into serious trouble.
 
1. Meth. Causes weight loss, face-picking, loss of skin elasticity, depletion of nutrients like calcium, leading to osteoporosis and tooth loss, meth mouth, and an all-over corpse-like appearance.

2. Alcohol. Red face, enlarged nose, beer belly, sagging skin, bloating, and rapid aging really take a toll on heavy drinkers.

3. Crack/coke/uppers. The sunken-face look, weight loss, and anorexic physique of uppers addicts like Lindsay Lohan, the Olsen twins, and Whitney Houston is pretty undeniable, though Hollywood likes to pretend it doesn't exist.

4. Heroin/other strong opiates. Many hardcore addicts look like straight up ZOMBIES, with pale skin, dark circles under the eyes, and either a disgusting bloat or excessive weight loss.

5. Tobacco. Yellow teeth, aged skin, dry smelly hair, bulging veins in the legs/hands, and that godawful smoker's cough...all very unattractive.
 
silentscience said:
it all depends on the amounts/frequency of use. any drug can change your appearance if you overuse it. I know for sure that special k, when overused caused me to get really skinny and pale...

generally though stimulants are the hardest on the facial features. they cause the most long term damage.
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^ This IME , i really remember looking like a zombie after some days on the stuff , it was with the only drug that my mum looked at me in a "hey i know you are doing something and you look like crap but no idea what is it" he.. 8) , never done meth im sure thats worst or beign really strung out on hard opiates
 
lol all of these meth posts.
gotta be crack, the worst depression shit a person could ever feel. the worst come down.sell your mother for another hit of crack. makes you either want a hit or just die.
meth is the "in" thing to say but no way . gotta be crack
 
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