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Most physically-changing drug.

I find it strange that noone has said coke, afterall its one of the 3(or 4 if you classify crack as a different drug) hard/bad drugs.

Does coke/crack really affect the way you look that much? Ive never met a crackhead or a bad cokehead so I dont know but I would have thought it'd do something physically negative, does it make you skinny or what?
 
from what i know, its kinda like a short lasting meth with more rush and just as many if not mroe negative long term health consequences and both with extreme levels of addiction potential.. im talkin about crack and ice here, smoking them.. really i dont know much about either drug and dont really want 2
 
Alcohol can also make people look terrible - but only in very large amounts. It can even give you a darker, uneven complexion eventually. Look at some hobos, they have a red/purple skin pigmentation. Can also cause weight gain and premature aging.

Crack and meth are probably the worst - at least out of common drugs - needless to say, see the stereotypical chronic user.

Some less common ones that are maybe worse for you than crack / meth but don't receive as much attention:

Chronic smoked Methaqualone use causes people to look at least as bad as crack/meth users - probably worse eventually - they lose their teeth even quicker. I think that eating them instead of smoking is probably not as bad for you, or your teeth, smokers are known to end up with permanent lung damage very quickly.

I've never heard of someone who used pure cathine (d-norpseudoephedrine) chronically in high doses - but I'd imagine it would cause 10 years of meth damage to your body in 1 year if you got high every day. It is much more harsh on the body but has a stronger (yet still pleasant) body load that meth lacks - which eventually turns into cramps, extreme weakness, twitches and nausea with daily use. Also has a stronger diuretic effect - all your water will be excreted via sweat or urination and you'll lose 5kgs (12lbs) in 2 days. It also causes your body temperature to increase significantly more. Probably I've never heard of someone abusing it for longer than a day or 2 before calling it quits.

Methcathinone is probably also just as bad for you as methamphetamine, having a stronger but unpleasant body load + more sympathetic nervous system effects than euphoria. The crash is far worse than meth - especially how your heart feels afterwards. IV'd methcat will lead to Parkinsons from impurities in the synth (Manganese).

I'd wager that chronic 4-MAR and Desoxypipradrol users end up looking as bad as the other strong psychostimulant users. But probably end up in psychosis more often.

The worst I can think of would probably be daily PMA use... If you could somehow manage to survive for longer than a year - you would probably be past the point of no return.
 
Most of them will over the long term...


You know what they say about MDMA though, if only you could look as good as you feel....

Meth does some pretty crazy shit to people....
 
If your talking about extended use of a drug, Id have to agree and say meth.

But in terms of which drug changes the way you look while your 'high' on it, id say MDMA.
 
In most cases it's not the drug that actually causes the physical changes, but the lifestyle and behavior you have while taking the drug. For example, many meth and crack smokers pick at their face causing pock marks, and most stimulant addicts don't eat properly if at all. While they are using, meth and crack addicts look terribly under-weight. Another issue with meth is the impurities that rot your teeth when it's smoked, or "meth-mouth". Take a look...

http://en.wikipedia.org/wiki/Meth_mouth

I also agree that severe alcoholics look noticably different with a red veiny nose, puffy features, yellow complextion from jaundice etc....and if a person drinks heavily, it doesn't matter how good they take care of themselves, the signs are obvious.

When someone takes medical amphetamines consistently, as prescribed, and takes care of themselves, then they dont really change physically. I was on 40mg of dextroamphetamine per day for 4 years, and I lost hardly any weight because I kept good care of myself. Heroin addicts often look sickly, but obviously if taken with care opiates cause no damage to your body directly.

People who sniff glue, gas, solvents, or any of the aromatic hydrocarbons long-term look pretty fuckin' sick...yuck!...
 
probably meth, dxm, crack, and alcohol...in that order

i'm surprised no one has mentioned nicotine, btw.
 
meth.. anything that lets you stay up for days not eating is gonna mess with your body hardcore
 
Meth...People will say that if you take care of your teeth you won't experience "meth mouth" but I've known a few people who smoked a lot of ice, claimed they took care of the their teeth; and their teeth still dwindled down to half their normal size and were grey/discolored.

If the shit does that to your teeth because of the "impurities"(poisons) what the hell is it doing to your organs?

Speed does exactly what its name claims. Speeds up your aging process about 20 fold.
 
I find it strange that noone has said coke, afterall its one of the 3(or 4 if you classify crack as a different drug) hard/bad drugs.

Does coke/crack really affect the way you look that much? Ive never met a crackhead or a bad cokehead so I dont know but I would have thought it'd do something physically negative, does it make you skinny or what?

when i worked in the ERs of south florida hospitals, the crack users were easy to spot with a look similar to the people on "faces of meth." we saw quite a few powder coke overdoses but those people didn't have the same kind of facial changes. i'm not sure about the reasons why but it was obvious who was smoking crack versus snorting or running powder.
 
When you say powder coke overdoses were they really bad, life-threatening cardiac or hypertensive crisis from doing rails or more as a result of panic attack?

I know it's not true but I've heard people say that you can't overdose by just snorting coke. Some people have weaker cardiovascular systems and strokes from snorting coke aren't that uncommon. But in a way I'd say that unless you keep your nose clean and have really, really good stuff, I don't see how you'd overdose, except have a panic attack. My nose gets blocked and I stop getting high after blowing everything out, the membrane is dry so I think it also causes it to only slowly get into the body after a certain point.

IN THE NAME OF HARM REDUCTION - DO NOT EVER THINK AN OVERDOSE IS IMPOSSIBLE WITH A CERTAIN ROA. Obviously you could artificially wet your nose and absorb more stuff quicker. Besides, the backdrop can also cause an OD if swallowed.
 
Meth may be the most physically changing drug on your appearance but heroin changes your soul. Once you become addicted you walk a different path than average folk. You'll push drug's harder than you could ever imagine just to stay well. For real , one time this dude tried to beat me for a few bag's and I hit him in the face with a 2 by 4. There's is no fucking with a junky in need :D
 
Meth changes people, and not just physically but REALLY changes them mentally. I had a good friend that got into it awhile back for a little bit and he would always act so much different once addicted to it. I would always get the infamous 5 or 6am phone call with a message like "DUDE! what are u doing on this FINE and BEAUTIFUL day? you shouldn't be sleeping right now!" and then I would call him back when i woke up around noon or whenever and he would answer the phone and be all like 'hello, what do u want, i need drugs' lol
 
When you say powder coke overdoses were they really bad, life-threatening cardiac or hypertensive crisis from doing rails or more as a result of panic attack?

I know it's not true but I've heard people say that you can't overdose by just snorting coke. Some people have weaker cardiovascular systems and strokes from snorting coke aren't that uncommon. But in a way I'd say that unless you keep your nose clean and have really, really good stuff, I don't see how you'd overdose, except have a panic attack. My nose gets blocked and I stop getting high after blowing everything out, the membrane is dry so I think it also causes it to only slowly get into the body after a certain point.

IN THE NAME OF HARM REDUCTION - DO NOT EVER THINK AN OVERDOSE IS IMPOSSIBLE WITH A CERTAIN ROA. Obviously you could artificially wet your nose and absorb more stuff quicker. Besides, the backdrop can also cause an OD if swallowed.

yes, really bad -seizures, strokes, brain bleeds like subarachnoid hemorrhage, cardiac arrest/
arrhythmia -all of which are often fatal. the strangest powder death i remember was a women whose partner had been putting coke in her vagina as well as on his penis. she rapidly absorbed a lethal amount of powder and arrived DOA.
very bad, very ugly, not a way i'd want to go out. no method of administration or form of cocaine is safe.
 
yes, really bad -seizures, strokes, brain bleeds like subarachnoid hemorrhage, cardiac arrest/
arrhythmia -all of which are often fatal. the strangest powder death i remember was a women whose partner had been putting coke in her vagina as well as on his penis. she rapidly absorbed a lethal amount of powder and arrived DOA.
very bad, very ugly, not a way i'd want to go out. no method of administration or form of cocaine is safe.

Thanks for the clarification, that's what I figured. Now I need to find the dumbest drug rumors thread and post - if it isn't already there.

Are any drugs given to combat the vaso-constrictive properties of coke? Any at all as a preventative treatment? The only vaso-dilators I can think of is weed and salbutamol. Both are probable worse for someone who is uncomfortable from too much coke. They will potentiate the effects due to their stimulant nature..
Would alpha or calcium blockers help - or is this potentially very dangerous. Could they prevent a stroke?
ACE inhibitors? They seem to have potential but I'm not doctor.
I know Beta blockers aren't recommended at all, people get flamed for recommending them so I won't go there.

I am not recommending you take any of the above drugs to prevent vasoconstriction.
But having a possible antidote on hand might be a good idea. in the name of harm prevention if one exists.

Thanks again, and sorry for the slightly OT - but we are talking bout possible prevention of heart damage by coke.
 
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Meth for sure, I take a lot of drugs, but that is one that I probably wont ever try... but then again i said that same thing about heroin... hahah
 
I originally said meth but some people are saying cocaine doesn't do anything to them etc, well I'm here to say I was addicted to cocaine 2x now, once at 16 and once at 18 years old, now I use it sometimes but not in too much access.

Coke does hurt your body a lot and can make you loose a lot of weight.

-dp
 
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