Methoxetamine - Tell Us More

[ColtDan]

never tried k before, but it was very confusing and retarded, i swear this stuff really does make you thick as shit afterwards, ive had a bad headache all day and been feeling rough as fuck. worse than a normal hangover for sure

 

[ColtDan]

followed by depression all day afterwards

 

[knock]

I did MXE and Ket on top of an evening's drinking session last night. I'm really lucky, I don't feel sick at all on dissociative/booze combos. But it does make me get into negative trains of thought. The pointlessness of life, the fuck up that I am making of life, etc etc.

Felt great all day today though, slightly funny head right enough but I am quite happy.

ColtDan - sorry it's having that effect on you! It has the opposite effect on me, but that's no consolation...

How big were those "lines" you were doing, and how many??

 

[Fishface]

followed by depression all day afterwards

You sure it's kosher?

 

[ColtDan]

the first time i mixed it with booze was fine, think i'll take it much more steady next time so this doesnt happen again

although i didnt feel dysphoric when i was on it, infact i felt a body high very similar to DMT. which is extremely euphoric

 

[ColtDan]

You sure it's kosher?

yeah its kosher

 

[lurching]

if i hit the ket (or mxe) after drinking a fair amount of alcohol, i get that horrible blurry/spinning vision that reminds me of being very very drunk. ugh.

 

[ColtDan]

yeah it kinda amplified the alcohol, but let me reflect apon myself so i was kinda awoken into a drunken state, like when i get drunk i kinda lose myself in a hail of oblivion and blackouts but, this kinda woke me up and made me aware, but added confusion and trippyness, it wasnt all that bad tbh just pretty confusing and i kept forgetting when i last re-dosed, and had a compulsive urge to re-dose cos for some reason i felt like i was doing meph and if i kept re-dosing i would end up nicely fucked.... but obviously the more i would re-dose the more twisted i would get. and i became quite transfixed on circles... and how everything is continuous... there was some deep shit being rattled around in my brain but i could hardly talk, or i would end up stuttering like a retard

i also delve deep into memorys on this stuff, it brings stuff back and allows me to reflect apon stuff, i think perhaps this would be ideal as a therapy drug or something? or perhaps a first time for someone looking to explore into harder psychedelics

my advise to everyone... dont mix this stuff with a lot of booze. it feels bad. i got drunk and did DMT a few times... and you realize how nasty alcohol is... makes you feel horrible

 

[Limpet_Chicken]

But, shambles, if one half-dies twice....what then? Or does one half to half-die twice consecutively to actually be considered one of the walking dead?

As for bupe, it isn't quite a pure mu-agonist opiate, it also has some kappa-ANTagonist properties, and I believe it is also an epsilon opioid receptor ligand, I THINK an agonist, but I am not 100% sure there. Norbuprenorphine may also bear some responsibility for either one or both of the abovementioned activities but again that is speculation on my part and I do not know for sure.

I found MXE not to go badly with alcohol, but I did not drink much (I rarely do drink enough to become more than lightly intoxicated, and have not had enough EtOH to have a hangover afterwards in years and years, possibly since before I was legally able to drink more than once or twice)

And a combination with 5-MeO-DALT...now that was a fuckin' blinder of an intense, but good trip, very enjoyable, and unlike either compound alone, very visual indeed.

Damn...I want some 5-MeO-DALT now, but I originally planned to go to sleep, before deciding to dose a couple of milligrams of desoxypipradrol and a handful of DHC pills up the chocolate starfish, to go on a computer-securing bender and get studying to learn C programming, but I can't trip now, as I took a dose of pizotifen in the hopes of staying asleep and I am pretty sure it would simply render inert any dose whatsoever of the 5-MeO-DALT, being that a strong
5-HT2a receptor antagonist is its primary mode of action. Damnfuck.

 

[fluffybudzz]

Alcohol didn seem to go too badly with it for me.

Weed after some mxe on the other hand got me completely fucked. My heart was racing so fast it was as if it was just vibrating, EVERYTHING was spinning around and morphing. All my vision was blurred, I couldn't speak. I really thought I was gonna die, but stangely I didn't care at all.. was very fucked up. Couldn't sleep until like 6am either. was mad. I have had very intense K holes and this was absolutely nothing like it. I could not shut my eyes and just let it take me, very stimulating.

 

[missimoo]

And a combination with 5-MeO-DALT...now that was a fuckin' blinder of an intense, but good trip, very enjoyable, and unlike either compound alone, very visual indeed..

is this a good mix? i thought maybe i wasn't dosing enough or something to lack visuals. DXM used to send me into space and have serious amazing hallucinations, for some reason since the MXE has been about its stopped working for me, I can do grams of DXM and get nothing. I wonder if this is due to the appearance of a new, more expensive drug suddenly...hmmm. still it has a distinctive taste and texture and remains the same. disgusting.

i thought it was just me not hallucinating!!! i feel better now will be doing this combo soon. shame the 5-meo-dalt makes me sick quite easily. 25mg i get maybe 30min trip. then it wears off. 50mg more intense 75mg and im praying to the porcelain god seeing 10x toilets swim around me for 5hours..

..re alcohol, earlier post a friend of mine had been drinking (not that much) on it and spun out. on a very low dose. it doesnt seem to effect me but like other people have said, not really a drinker, infact i hate alcohol. it is "the chav relative of drugs" for me.. an utter no no. (unless its cocktails...)

 

[Limpet_Chicken]

I have had CEVs on MXE, well, not exactly, more like scenes unfolding before my mind's eye, never 'visuals from the eyes' for want of a better descriptive phrase, but NEVER visuals open eyed even on high doses of MXE. 5-MeO-DALT isn't very visual at all for me, whereas DMT produces vividly intense CEVs, and if I smoke enough, visual intensity sufficient to make it impossible to distinguish between having open, or closed eyes.

MXE+5-MeO-DALT though, proved quite visual although not intensely so.

Ket, I found very visual with eyes closed, although sadly I only ever managed to obtain any a couple of times, last time I tried it, I was seeing a r'yleh-style sunken city-sized building of incredible complexity and intricacy rise before my eyes, and as it was wearing off sufficiently to enable walking (or rather walking-ish), produced profound alterations of depth-perception, walking down the road to meet up with my then fiancee, I thought she was way off, up the road I was walking down, only to find she was mere feet to meters away. Never experienced much interference with depth-perception with MXE.

Anyone here tried 3- or 4-MeO-PCP or their corresponding hydroxyl homologs to contrast, visually? or care to provide a comparison between ket and MXE, visual/sensory perception wise?

DXM...ick, I have tried downing cough syrup, and the most effect that EVER produced was a drunken, intoxicated feeling, and blurred vision followed by intense nausea, that was the single, lonesome time I got any effect apart from plain vanilla nausea off the stuff, I ended up staggering into a pub in manchester town center, going to the bog to chuck my chickens, and after spraying the wall with what probably turned into lurid pink plastic, embedded with bits of chunky pre-owned semiliquified dinner other times I tried using jelly pastilles, tablets, and pure DXM HBr lab-grade powder, without any effect whatsoever.

No idea why, but it seems like I am actually virtually immune to the effects of DXM, I doubt very much indeed it is to do with a CYP-p450-2D6 deficiency preventing conversion of DXM to dextrorphan, as I get great results with codeine, in fact I suspect, that I might actually have a high-CYP-p450-2D6 phenotype, as 500mg of codeine provides far greater euphoria than a half gram of dihydrocodeine tartrate (irrespective of my opioid tolerance at the specific times in question, comparing both side by side on different occasions within a few days, and it lasts far, far longer than does DHC for me.

And DHC is known to be active in and of itself, dihydromorphine apparently is not the chief active metabolite, so I would make a guess that it is more effective in those of a
low-p450-2D6 phenotype, and that those expressing the enzyme in greater amounts may find that dihydrocodeine works at least to some extent, whereas they gain little, or no analgesia or euphoria from codeine itself.

As far as 5-MeO-DALT goes, it seems to take a lot more than is typically reported by many users here to get me where I want to be when smoked, although I haven't yet tried it orally, I plugged it when I did the MXE/5-MeO-DALT combination and that was pretty intense. In fact given the experience with it so far, I don't even bother weighing the stuff out at all, I do NOT say that as a reccomendation or encouragement for others to do the same, but from experience, I feel totally at ease eyeing it, and indeed using however large a dose, within reason, by eye as I feel like at the time, although then again, I never bother weighing DMT either, as the latter seems to agree with me, and I can judge to a decent extent by eye, after grinding to a fine powder what a given amount will do, and am quite comfortable with pretty large doses of smoked DMT.

 

[SpecialK_]

MXE and alcohol work fine for me, I always love throwing a bit in but I'm the same with k too. It's likely you'll get a little dizzy but if you can get over that you'll be feeling great, feels a bit like being blocked, very lucid dream-like state while having sensations of being pulled/pushed slowly like on k or mxe, really interesting mix.

 

[Chatative]

I personally find MXE and Alcohol to be a disaster. I think it must vary from person to person but I reckon it's best to avoid probably anyway.

Once I had only had a couple of bottles of beer and the MXE just sent the room spinning badly and I hurled.

The other time I wasn't drunk, a little tipsy perhaps, but I'd had a few and I have no idea what happened after a certain point. One moment I was in my bedroom getting nicely wobbly and about to go to bed and the next I woke up fully dressed in my bed 3 hours later having hurled over the side. I think the MXE must have basically just combined with the alcohol to give me a bad alcohol blackout. Not something that normally affects me plus I hadn't drunk that much.

I kind of assume from the fact I don't remember going to bed and that I had been sick over one side of the bed and moved to the other that I was corpus mentis and hadn't passed out or anything but who knows. Was a bit unerving when I came to/woke up or whatever and realised I could have aspirated on my vomit

Both times the MXE doses had been fairly low.


Another problem I find is eating before taking MXE. I seem to have quite a low tolerance and I find literally 10mg too much or re-dosing 20 minutes too soon causes me to get small waves of nausea. At least it seems to be connected to that. It passes very quickly - maybe 30 secs to a minute but if I've got anything in my stomach there's a fair chance it's coming back up. I've yet to see if using a different ROA to insufflating stops that.


To be honest I've sort of been put off MXE with all the problems here and there. Have been fairly sensible using it on the whole but there always seems to be something cropping up. YMMV I guess, it is a nice drug just not one that seems to agree with me.

 

[SpecialK_]

Just wondering what method you all use when dosing with alcohol? I recommend sublinguial (although I recommend using MXE this method any way) the onset is slower and much more tolerable compared to sniffing it, less overwhelming and gradual allowing you to have time to adapt to it rather than spinning out.

 

[Limpet_Chicken]

I insufflate almost always, although if I want a real strong kick-up-the-arse (pun intended) then the arse is where it goes.

And I drink AFTER it kicks in, not before, never done it with beer, etc, only ever vodka, and neck a couple of shots, then wait until its fully kicked in before drinking more, I think the key to a decent experience drinking on MXE is to do so after the MXE, to drink only moderately and then space out one's drinks.

As for how to take MXE...the taste alone is a good reason to snort it, well, that subtle smell contributes to the 'flavour' I taste after a good line/bump off a key etc.....gah you bastards, getting me thinking of that taste, I want some MXE now damn you all to perdition!

 

[HouseFever]

But it does make me get into negative trains of thought. The pointlessness of life, the fuck up that I am making of life, etc etc.
?

ahh I get this is on MXE, it makes me think of all the negative shit in my life, and makes me think I'm a worthless waste of space. K does not give me these negative trails of thought, so i'm leaving the MXE alone.

 

[Limpet_Chicken]

One thing I have noticed, is that after a period of several days use (small bumps throughout the day here and there, enough to cause light to moderate dissociative effects, but not enough to impair motor coordination more than slightly) that my cognitive and executive difficulties are nearly wiped out, and I feel refreshed, motivated and more clear headed than I have in years. This effect lasts for several days to nearly a week after several days usage and subsequent discontinuation, and is most definately NOT merely a return to baseline feeling comparitively bright eyed and bushy tailed in contrast with being cognitively scrambled whilst actually under the influence.

Not sure if this would apply to a single moderate to large dose on a single day, or repeated small/moderate dosing throughout one day, but I do intend to find out, it made for an odd nootropic, of sorts, at first impairing while acutely intoxicated, then the days after, absolutely brilliant.

I am not sure why its doing that either, as it can't be due to antagonism causing upregulation of the receptor, thus acting in a way, like an AMPAkine, but at the NMDAr instead of the AMPAr, as NMDA receptor expression is modulated by the amount of input received by AMPA receptor mediated stimulation, and thusly NMDA receptors downregulate in response to antagonism as well as overstimulation by glutamate (which would be dangerous due to excitotoxicity in any more than a slight increase in stimulation by an orthosteric agonist)

 

[SpecialK_]

ahh I get this is on MXE, it makes me think of all the negative shit in my life, and makes me think I'm a worthless waste of space. K does not give me these negative trails of thought, so i'm leaving the MXE alone.

I find that it gets negative and that you'll come up with crazy ideas on it while never actually doing them. Although this was only with daily use and it could be ignored.

I found it can give a real euphoria afterglow, made me feel great for days after.

 

[davez]

ahh I get this is on MXE, it makes me think of all the negative shit in my life, and makes me think I'm a worthless waste of space. K does not give me these negative trails of thought, so i'm leaving the MXE alone.

+1 I'm calling it quits on drugs now or at least trying to.