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Dissociatives [Methoxetamine Subthread] Adverse Effects / Side-effects

I have written quite extensively in the previous MXE thread about the side effects that started to appear when using MXE.

The first 1,5 years went great, I used it and abused it just about every weekend and sometimes also on weekdays many days in a row. I sometime took it 5-6 days in a row after work in doses of 15-25 mg just to relax. On weekends my doses were everything from 35 to 140 mg.

About three months ago everything started to go wrong with MXE. It had went perfectly together with tryptamines but now it produced hypertension, anxiety, extreme confusion and a complete wipeout of my short-term memory. It systematically ruined all tryptamine trips. Then side effecs started to appear with MXE alone; hypertension, extremely high blood pressure, agitation, dysphoria and extreme confusion. It also started to impair my speech so that it became so slurry and sluggish I could barely speak. These symptoms never appeared the first 1,5 years.

I've never done anything stupid or dangerous while on MXE. The side effects came lingering slowly after using the stuff too often and too much.

I'm now on a break from MXE. I haven't touced it for over a month and will not touch it for at least 6 months. I've lost all magic and MXE just produces nasty and freaky side effects. Sad. I loved the stuff and I don't know if I've ever regain the magic.
 
Have noticed some urinary retention since I started using MXE in Feb 2012. It seems to take longer to get all the piss out at the end. I have always had it where I get some dribbles, but now I have to wait a little longer because there's usually much more piss left over than what it was before. Going to considerably cut down my usage. To note, this has happened after basically daily usage over the space of about 2 months.

EDIT: I have noticed that this symptom has since gone away.
 
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The only negative thing I notice is mania. At least when I come off of it, I would feel hyperactive, stimulated and taking another dose would mute that feeling.
There is the aftereffect mania I experience and if I binge for an extended period of time there's also the after day mania to where depending on how long I've binged for is how strong it is.

In my experience after binging for over a week, I would feel as if the world revolved around me. I would get delusions of the form to where I felt like I was extremely powerful, and everything is about me. I find that taking a benzo stop this. Or I could just take a 2 day break and it would be over.

-PLUR
 
Or I could just take a 2 day break and it would be over
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Yes, this is a very fortunate thing about MXE, given how much it can affect your personality and how intense it can be. Thankfully it only takes a couple of days to come back to normal.
 
The high blood pressure, very elevated heart rate and mania, Can be experimented with spacing normal dosages? Or this side effects only occurs with "binges" and very high doses?
 
I noticed a new side effect, anterograde amnesia.

I never got it to this extent before. Last time I used I found myself in a situation, and I couldn't really explain how I got there. No need to say it was a rather ridiculous situation, which is nothing new in and of itself. But I used to always remember the trains of thought that made me do these strange things. This time it was just *dose*, *???*, *teleport*.

Moreover, I promised myself to log every dose of MXE I would ever take, as a kind of safety mechanism (and because it shifts the focus on doing research like a rogue scientist, instead of just going nuts on mysterious new drugs like a crazy addict). And now I'm sure I must have taken an unregistered dose. The log says I never should have M-holed (20mg oral, 35mg rectal). But that had to be a hole, and I found two used oral syringes in my trash the next day. Wtf, I only needed one.

I don't remember going "let's cut that registration crap and just get high". I was honestly surprised I apparently had made such decision. No memory of it at all. It's as if some dissociated fragment of mine (in the clinical, cognitive psychological sense) had taken over. I love dissociation, but if it can evolve to blatant DID-like phenomena, then that frightens me. If longterm use persist, it could be that the drug would become technically uncontrollable, since the "I" in control disintegrates, really dissociates.

So yeah, breaking news, dissociatives might dissociate you... :\
 
has anyone vomited from MXE yet? when I snorted it I feel like I got pretty close, I was a bit nauseous but I just laid down and let the drug take me and it went away.

Also I had a pretty ridiculous fear that every time I had to fart I thought I was like pooping hahahahaha so I like was afraid to get up and check.

I also had the impression that I was going to die one time and accepted the fact that me as a person would be dead soon and it ramped up the trips intensity
 
SONN said:
has anyone vomited from MXE yet? when I snorted it I feel like I got pretty close, I was a bit nauseous but I just laid down and let the drug take me and it went away.

Also I had a pretty ridiculous fear that every time I had to fart I thought I was like pooping hahahahaha so I like was afraid to get up and check.

I also had the impression that I was going to die one time and accepted the fact that me as a person would be dead soon and it ramped up the trips intensity
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they are not side effects, rather just your own anxeity of not knowing whats going to happen or being scared of what's happening.
 
I only tried small doses of MXE (no more than 10 mg), and always when I go to bed I get mild CEVs. Even more than 12 hours later after the dose. It usually happens to me with DRIs.
I am the only one?
 
I get what I would call fairly strong CEVs on MXE, at least strong for a drug that's not primarily a hallucinogen. I have HPPD though, so even marijuana gives me mild CEVs.

I have one symptom that I don't think has been mentioned yet, to quote myself from another thread:

My girlfriend tells me that I sleep all crazy the night after I do mxe. Apparently I wave my arms around or just hold my hands up in the air. Last night she said it looked like I was trying to fly a spaceship because I was moving my hands and arms around so much, she had to hold my arms down until I stopped so I wouldn't hit her.
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Anyone had any urinary/bladder problems?

Since using MXE (starting in Feb), I've noticed weird symptoms (I swear my urethra feels tighter. Am a guy btw). I get this sensation that all the pee never fully comes out and I'm left with some "stuck". Perhaps something is inflamed? Whatever it is, things overall just don't feel "right" down there.

There is a chance though that it could be psychosomatic. I worried that using MXE would damage my bladder, and I seem to be experiencing those symptoms. It could all be in my head.

Something to watch out for though.
 
I'd expect similar bladder/kidney problems with Methoxetamine as people have seen with Ketamine yes. Although Methoxetamine was developed to avoid these problems, this was done by finding something as potent as Methoxetamine that would allow you to consume a much smaller amount of powder. E.g. 50-70mg instead of 200-250mg to hole intranasally for some people.

Now of course if the powder were to be just as damaging as Ketamine to the skin tissue, that'd mean you'd have to dose 3-5x as often to achieve the same damage. However the issue is Ketamine bladder/kidney damage can show up very quickly in many individuals in the first place, so that's still not a whole lot of usage for MXE before similar problems arise.

How often/how much have you been using? If it is a real problem and if it was caused by the MXE it'd be good to know how much you consumed so other people can be more careful.

One thing I will say is to stop consuming any more for now, even if it is psychosomatic it's better to be safe. The effects you described sound like it could be a UTI (Urinary tract infection), and this could have been caused due to MXE use or something else entirely.

If you're still experiencing this in a week or so then go to a doctor and get it checked out, you don't have to mention any drug use, as UTIs aren't as rare as you might think.

It's also possible that it is psychosomatic, as I actually had something similar way before my drug use, got various check ups from different specialists, who all suspected different things - and then eventually it was found that physically nothing was wrong with me, so it was all in the head. Funnily enough as soon as I realised that myself, the problem vanished.
 
Thanks, Jesus :)

Jesusgreen said:
How often/how much have you been using? If it is a real problem and if it was caused by the MXE it'd be good to know how much you consumed so other people can be more careful.
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I used about 3-4 grams in 3 months. Using basically every day for the first 2 months, and then skipping some days in the next month, but generally doing it quite often.

[EDIT] After thinking about it, I'm not actually entirely sure how much MXE I consumed. It could be a gram or two more than what I stated. My memory is pretty terrible at the moment.
 
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Other than its addictive properties, the only negative side effect of methoxetamine that I have observed thus far is that it sloooooows you down. Intellectually. Methoxetamine, and all other NMDA antagonists really, are like a simulation of being short about 30 or 40 IQ points. Normally, I'm pretty slick when I need to be, but I tried pulling the wool over someone's eyes the other day while peaking on MXE. Wow, that fell flat on its face. He called me out on my bullshit in the blink of an eye. Note to self -- successfully lying requires an IQ above 70. :P
 
TheAppleCore said:
Other than its addictive properties, the only negative side effect of methoxetamine that I have observed thus far is that it sloooooows you down. Intellectually. Methoxetamine, and all other NMDA antagonists really, are like a simulation of being short about 30 or 40 IQ points. Normally, I'm pretty slick when I need to be, but I tried pulling the wool over someone's eyes the other day while peaking on MXE. Wow, that fell flat on its face. He called me out on my bullshit in the blink of an eye. Note to self -- successfully lying requires an IQ above 70. :P
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I find this aspect of mxe to be incredibly frustrating!
 
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