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Dissociatives [Methoxetamine Subthread] Adverse Effects / Side-effects

Noticed im thick as shit on MXE, even working out basic things, seem to feel sharp and clever the days after though
 
Besides realizing theres not a lot of gain i can get from mxe besides fun some other negatives have made me decide to use it faar less frequently. As it is I barely use it, at this point its been at least a month and a half? or more I dont really remember. I feel like it brings out a side of myself I dont really like, maybe it takes some day or uses to come out but I feel like a version of myself that I dont like. I think the mxe is to blame, though i suppose some other things could possibly. More self serving, etc. Ive heard other people describe NMDA agonists as causing this so its not particularly surprising to me, I just dont want to dislike myself.

Also I feel like I can noticeably notice mental deficits when I use it, they must be caused by it, since now that I havent done it in a while I dont notice them at all. Slight memory holes, like the connection to a word is missing. Just feeling like I am not functioning at peak performance. With a pretty demanding and competitive course load at uni i cant really let myself do that. I will note that I generally will use some etizolam and weed with mxe and its possible that is playing a factor as well. Im sure ill take it again, but ive gotten over the idea of using it with any sort of frequency.
 
I'm still wondering if MXE is more physically harmfull than Ketamine (in general, short term and long term), are there any valid conclusions yet or is it too early ? And continued cognition impairment is part of what i call physical damage too.
 
coolcucumber said:
I find this aspect of mxe to be incredibly frustrating!
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By the way, I forgot to mention, it gets better with practice. When you're first confronted with the NMDA-antagonized state of consciousness, your brain doesn't really know how to deal with it. But, after visiting that dissociative state time and time again, you seem to learn to work around the intellectual barriers that the drug puts up.*

*I'm somehow convinced that all of the interesting and significant effects of NMDA antagonists have to do with developing new informational pathways in your mind, in your brain's attempt to circumvent barriers. It's all about barriers...
 
coolcucumber said:
Anyone had any urinary/bladder problems?

Since using MXE (starting in Feb), I've noticed weird symptoms (I swear my urethra feels tighter. Am a guy btw). I get this sensation that all the pee never fully comes out and I'm left with some "stuck". Perhaps something is inflamed? Whatever it is, things overall just don't feel "right" down there.

There is a chance though that it could be psychosomatic. I worried that using MXE would damage my bladder, and I seem to be experiencing those symptoms. It could all be in my head.

Something to watch out for though.
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I had these exact same symptoms after taking far too much MXE last summer. I went to the doctor and it wasn't a UTI. I am leaning towards it being psychosomatic because like you I was getting paranoid about bladder damage. It went away after a couple weeks of abstinence and hasn't reoccurred.

The doctor told me I was dehydrated and so there were some crystals in my urine, and she guessed this was the cause. MXE causes dehydration in a lot of users, so that might be the cause. The sensation can also be caused by imminent kidney stones.
 
Think mxe has caused a bladder infection, gonna lay off it for a little while. probably doesnt help with the amount of alcohol i drink either
 
ColtDan said:
Think mxe has caused a bladder infection, gonna lay off it for a little while. probably doesnt help with the amount of alcohol i drink either
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How do you know that? Bladder infections can occur naturally just because you're taking MXE doesn't mean every ailment you get is due to it.
 
TheAppleCore said:
How much do you want to bet that you'd score lower on an IQ test if you took it on MXE?
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^ This. Unfortunately MXE can cause quite a few delusions when high as most of us have seen, and it's easy to think you're extremely smart while under the influence, even more so than normal, and that all of your ideas are the most grand wonderful things that any mind has put into existence. In 99% of cases if you take another look once you're sober a few weeks later you'll laugh at those ideas ;)

I've witnessed people doing the most stupid things imaginable on MXE, and it certainly seems to slow down both mental and physical co-ordination. The issue is, this is likely coupled with a big boost of dopamine that gives you the confidence to think you're thinking at normal speed or faster.

BruceLeeSwag said:
How do you know that? Bladder infections can occur naturally just because you're taking MXE doesn't mean every ailment you get is due to it.
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While that's true, it's a safe bet to lay off the MXE for a while, as like Ketamine it should be quite damaging to the bladder and kidneys after prolonged use. As I mentioned before, people often are under the impression that because MXE was designed to reduce this sort of damage that it doesn't cause it - but that's due to having to consume less, and if you're consuming the same amounts as with Ketamine, or using it very regularly, it should.

The issue may or may not be due to his MXE use but at the very least even if it is unrelated using more MXE would likely exacerbate the problem, so laying off it is certainly the right decision.
 
I used about 5 grams of ketamine in about 3 months, dosing every few days at about 80-150mg. I have noticed some bladder problems retrospectively. I have noticed a reduced ability to stop myself from urinating, when I need to pee i seriously need to pee or I will piss myself. This doesn't happen often, but when it does it is quite alarming to literally have to run to the toilet. Though my bladder seems to be fine if there are no toilets and I know that I can't go to the toilet, I'm fine, but if I know there's a toilet I can use and I need to pee it's unstoppable. Strangely I never noticed any of these bladder related effects while on methoxetamine, what I noticed was that it made me need to take a shit frequently. It gave me gas and often I took a shit (sometimes 2) almost every session I dosed. At the time I thought it was funny but now I think that it was likely causing some damage, I had a period of about 2 weeks where I had terrible diarrhea, at the time I thought it was due to food poisoning or something but now I suspect methoxetamine was at play, as I was using it frequently in that time and I was dosing it orally quite often.

I deeply regret my usage and hope that these bladder issues clear up, methoxetamine was advertised to me as Ketamine without the negatives on your bladder and kidneys and that seems to have been a lie.

On a side note, to anyone wondering about ethylphenidate? Don't do it, it's highly corrosive to your sinus or any other part of your body, including unfortunately your bladder (and likely kidneys). I have spent the last day experimenting with it and am experiencing some real discomfort in my bladder and groin, something that methoxetamine never gave me (I would occassionaly feel like I could feel my lower disgestive system working, but no discomfort). I am guessing that this is a case of the corrosive nature of ethylphenidate exacerbating the damage methoxetamine caused.
 
^ Yeah Methoxetamine certainly isn't without the kidney/bladder damage. It was designed to reduce it, but the way it was designed to do so was by finding a chemical more potent by weight than Ketamine - so you only have to consume say 70mg instead of 200mg+

That doesn't mean the damage isn't there, simply that you get more doses from Methoxetamine before the problems arise - meaning it's less likely that infrequent users will run into the problems, but regular long term users are likely to hit them eventually regardless of what they do.
 
At least this is the theory. But keep in mind that not much research has been done on methoxetamine. It is possible that we find out in a few years that the different substitution pattern actually increases the potency for kidney/bladder damage - relative to ketamine -, in a way that both smaller doses and increased potency for kidney/bladder toxicity even out at a level similar to ketamine. Nobody knows that for sure atm.
 
The bladder problems with both of them are confusing to me. I have done ounces of ketamine to myself and know people who have done much more than me and never experienced any bladder problems. Not at all to say they don't exist. But I think the above poster is correct in saying the reduced damage with smaller amounts of methoxetamine are strictly speculation at this point and should not be an excuss to abuse methoxetamine and expect not to have any consequences.
 
I was never a heavy user of MXE -- my peak usage was around twice per week, and that didn't last very long. However, lately I have noticed some bladder weirdness as well. I now seem to experience a continuous "bladder awareness". It's subtle, and it's not painful by any means, but if I pay attention closely, no matter how recently I have urinated, I feel a light sensation resembling the need to urinate. It's not so noticeable during the day, but for some reason it's very distracting at night when I'm attempting to sleep. I also feel like I urinate more often now, but that's difficult to verify, because I never exactly recorded my urination frequency in the past.

Considering the fact that a number of users seem to tolerate much heavier consumption without suffering bladder issues, and also the fact that human beings are fairly suggestible, it's hard for me to work out whether or not I'm just paranoid. In any case, I think I'll lay off the MXE for awhile, to see whether or not the symptoms fade.

I would really like to hear from more frequent / regular MXE users -- have you experienced any bladder related symptoms?
 
Methoxetamine - and I guess most drugs in the NMDA antagonism class? - decrease my ability to learn (i.e. grasping new concepts, developing novel solutions to problems, etc).

I'm a software programmer so my day job involves a large amount of problem solving - when I went through a bit of a phase last year with MXE, I found it progressively more difficult to understand and solve problems the more I took. I think this is probably the most worrying aspect of MXE abuse for me, because it took a _long_ time to realise this was happening (weeks if not months), so while everyone around me could see I was struggling to do my job, I was merrily sitting in a fluffy cloud thinking "cor, this is a really tough bit of work I'm doing - I'll be so proud when I've finished it".

Reminds me of how I used to feel when I made awesome dinosaur drawings at the age of 5...

;o)

/al
 
^ Yeah, the way I see it, NMDA antagonists severely decrease intelligence, at least while you're high. I never noticed any negative effects after I sobered up.
 
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