How can IT be that IV coke has more change of leading to od? I know its effects on the heart are much worse, but IV Meth, which I never did, seems so much more demanding (for Both mind as body) and seems.so much more destructive, like tooth decay, starvation and sleep deprivation and more psychotic tendencies, that Both od and degenerating faster is more likely on coke seems very contra intuitive to me?
Can you explain and elaborate some more?
I’ve looked for any research that compares the relative chance of overdose between Cocaine and Meth - but there isn’t anything that discusses the two together. So I need to rely partly on my own IV experience of both drugs and research into IV overdoses of the two drugs independently of each other.
Firstly, I have overdosed several times on IV cocaine. By which I mean become almost instantly unconscious and often vomited. Sometimes it was a straight blackout and sometimes it was a short but massive rush (a ‘bellringer’) that caused me to keel over and be aware that I was (and assuming death).
However, despite inadvertantlly taking up to 5 x my intended maximim dose of meth in one shot (and overdoing it many other times), i have never felt close to death, never vomited, and never felt close to passing out. I have though massively ‘overamped’ and had a few hours of profuse sweating, fever-level temperature, blurred/double vision, and difficulty standing. However each time I was able to keep calm, cool myself down, and fully recover with no obvious damage.
My cardiologist told me that cocaine is far more cardiotoxic than meth and a 1 year coke user can have far more cardiac damage than a 10 year meth user. There are many journal articles that unambiguously confirm the cardiotoxicity of cocaine - but with meth the research is far less conclusive (although no-one doubts it does do damage).
In both cases the mechanism of cardiotoxicity is not 100 % clear. But it seems that cocaine causes more specific/local vasoconstriction in and around the heart - leading both to acute myocardial infarction (heart attack) even in healthy people and to chronic damage even with modest use. There is just not that much evidence of acute myocardial infarction in healthy people from shooting meth and the long term damage seems to progress more slowly even with chronic use.
However: there are definitely many case studies if apparently otherwise healthy people dying from a cardiac complication or stroke after shooting meth.
The absolute risks of shooting meth are significant. It’s very dangerous. But I am talking about the relative risk compared to shooting coke. It’s even more dangerous. Bordering on insane.
)
