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mephedrone long term negative effects progress reports

melange said:
check for hyperthyroidism
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I've had a Thyroid check a few months back, came back normal. I'm going to the docs in a few days about my eye, so I'll ask him again.

I've developed a black spot in my left eye that's been there about a month now. Hopefully this isn't a retina problem caused by hypertension/drug abuse, I vaguely remember getting an angle grinder spark in there though so hopefully it's that :D

Oh, Hi by the way. Been lurking on this forum for years - just never had anything to add really. Just read everybody elses discussions :)
 
I've used Drone a few times... I find it to be a powerful stimulant with empathogenic qualities. It is similar in feeling to mdma & cocaine & speed. But it ISN'T mdma, cocaine or speed, it's a new chemical, unresearched & unregulated in it's production & it should be treated with the utmost repsect! I'm using only a few lines in an evening, for a couple, maybe three hours at most... My lines are tiny 10 or 15 mg's & the effects are subtle & pleasant, enhancing music & other sensory activity. I feel an increased heart rate & general energy. However, anxiety increases as redosing continues which is why I'm inclined to keep my sessions short & dosage low. I also noticed coldness in my extremities but no discolouration or anything. I cant stand that sketchy comedown shit so normally take small doses of valium post-mdma/coke/speed so it wasnt difficult to control excessive stimulation as the drone wore off.

Just thought I'd post my experiences up to now, a few weeks after my first Mephedrone hits... I havent got thru the first gram yet... my gf has had a little bit, less than me.
 
Well, my knees always have a red tint to them now, and if I use Mephedrone or any other stimulant this comes out more fully. I still enjoy what I have left of these drugs, but I'm glad they're leaving the scene, they weren't good for me.
 
I guess I didn't stop early enough. I quit yesterday and got rid of all my supply, however my heart is genuinely screwed up. I've not had any tests yet but I will do and I'll post the results. I feel hugely unwell physically, well, that's what I get!
 
All significant side effects seem to be after 2+ day binges rather than singular, 'sensible' use for me. Usually going through around a gram per day of the session.

The first time this happened on day 3 I had to go to work (I'd not slept for 2 days and felt physically exhausted but mentally fine..no 'crash'). For around 3 hours at work I was breathless just sat down not moving, my heart was racing but I couldnt feel palpitations, it just felt very fast when I checked my pulse. I wasnt breathless in the respect of feeling the need to go to A&E, I was just breathing much more rapidly and it felt more of a mild annoyance than a concern - although I'm sure it wasnt good! I've had this a couple of times since and have now knocked mephedrone on the head...

That's the main issue for me, I havent had any of the purple knees etc but I have noticed some tingling/numbness in my extremities the days/week after a session.

I also get really bad stomach discomfort especially when taken orally. This feels like severe bloating/acid and I've literally been doubled up with it before. Also had some nausea and vomiting on a couple of the comedowns.

This isnt really a significant side effect but I've noticed I get really bad gurning and eye wiggles on mephedrone. I never really got much of either on mdma or other drugs but meph turns me into a complete mess.
 
I'd love to say this is due to a binge, but I was getting mildly hypoxic last night, I feel pretty ashamed about this all, I will try and get an EKG done. Last night I was getting mild heart pains, shooting pains down arms, numbness etc. These are all symptoms of pretty serious heart issues and I will be going to the doctors soon. I didn't call an ambulance because quite frankly, I really don't think I could put my family through that. I'm just telling everyone here as advice.
 
Thought I'd add my 2 cents to this thread.

Earlier in the month I had what I would consider a binge on this substance. I consumed maybe 5g in 7 days, with two 24 hr. breaks near the beginning. By this point I had definitely noticed some persistent vasoconstrictive side-effects such as coldness of the extremities / decreased capillary response. Nothing alarming, though I noticed the effects seemed greatly potentiated by nicotine and other stimulants, particularly mephedrone itself.

The next night, having consumed ~1g the previous day, I took a single oral dose of 175mg and relaxed into a bath to wait for the onset. At about T+20 min., I began to feel a little dizzy and noticed some changes in my vision. I do usually get some slight visuals at the beginning of a meph session, but this time everything seemed unusually blurry. The effects worsened over the next 2 min or so, and I was starting to get more dizzy and confused. I started to get a bit worried and tried to take my pulse, but it was too uncoordinated to count. I decided to get out of the bath and find my wife, who is a nurse, in case I lost consciousness or something.

She laid me down and listened to my heart in about 2 dozen places before proclaiming "you have an S3 gallop." Peak HR was about 160, BP was not taken. I didn't get much more out of her as she was trying to change the subject to calm me down. By this point, I was feeling significantly better and coming down a bit. My pulse was starting to even out, and HR was around 110. I was pretty relieved, but too shaken to redose and just rode out the rest in bed and fell asleep. Felt reasonably normal the next day...

Anyways, I did some research and learned that the S3 gallop sound is not good at all. If chronic, it is a sign of impending heart failure and can be acutely caused by, among other things, fluid overload. I certainly didn't overload on fluids and my only guess is that the vasoconstriction was severe enough to significantly raise the fluid volume in my heart and larger blood vessels.

Despite the scare, I still managed to talk myself into dosing again 48 hrs. later, and ended up consuming another g in < 12 hrs, finishing off my stash. Now I would like to think I've sworn off the substance for good, but I don't honestly know if I could consistently pass up the opportunity to do it again. Brain likey mephedrone. Heart not so much...
 
I used 150 mg one time and felt like had I taken 200 mg would have over dosed. I felt the strongest rush I've ever felt, It is my opinion that it is working as a releasing agent while inhibiting reuptake. I could feel The toxicity happening in my brain. I was scared to death for about 20 mins. I flushed the rest of what I was given. Mephedrone is not fit for human consumption.
 
The amazing euphoria of the first 5 or 6 times I will never recapture, and that's the worst thing about it. I've never gone more than a week, for 5 months, without having at least half a gram. Over the past month it's usually been as frequent as every 2 or 3 days.

Financially I simply can't afford to go on, especially now that it has become illegal in the UK and prices have tripled. I don't consider this drug particularly addictive...but I did find its lure hard to resist when I had it in my posession. It will be a sad day when I finish off what I've got, but it's definitely for the best. All my sessions have been insufflated and my nose and sinuses have been raw for a long time.
 
efc18 said:
the amazing euphoria of the first 5 or 6 times i will never recapture, and that's the worst thing about it. i've never gone more than a week, for 5 months, without having at least half a gram. Over the past month it's usually been as frequent as every 2 or 3 days.

financially i simply can't afford to go on, especially now that it has become illegal in the uk and prices have tripled. i don't consider this drug particularly addictive...but i did find its lure hard to resist when i had it in my posession. It will be a sad day when i finish off what i've got, but it's definitely for the best. All my sessions have been insufflated and my nose and sinuses have been raw for a long time.
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orly?
 
against my best judgement (and for odd ethical reasons too involved for me to explain here) i decided to take a 100mg dose of mephedrone intranasally to evaluate its effects. before and after i ingested a smorgasbord of antioxidants including acetyl-l-carnitine, alpha lipoic acid, COQ10 and melatonin as well as 5mg tadalafil to combat the anticipated vasoconstriction.

the material was crystaline and smelly. i found it to be very MDA like, some visual distortion, warm "softening" effects and quasi-psychedelic ideation. it was highly entactogentic and sex on it was transcendently good, the only drug that has been better is LSD. otherwise it felt toxic and uninteresting. the euphoria was really brutal i could not even stand up - the idea of taking this in a crowded club or bar seems insane - i would have doubtlessly vomited. the only thing it had in common with cocaine was an unreal hangover, slept for 12 hours and felt unmotivated and depressed for an entire day. i would bet my life this stuff is having a significant effect on serotonin receptors. i hope the various prophylactic measures i took prevent any long term damage.

after seeing how strong this stuff is i feel much worse for the people who are consuming multiple grams in a night :(
 
An euphoria so strong you can't stand seems too much for just 100mg, but everyone's different right?

Anyway just wanted to update saying that after basically almost 1 year from the last of 3 meph sessions (consisting in 250mg over the night) in which I abstained from everything except kratom, last week after consuming some raw cacao nibs along with the kratom I woke up the next day with arrythmia, maybe an extrasystole. Now I can't of course blame meph for this and everything that happens involving the ticker, but it still sounds weird that the caffeine in the cacao nibs caused this. Also have to add that after this for a couple days I got again the palpitations I experienced after meph. Now the whole thing is subsiding, but still present in the morning when I wake up.

And yes, that meph is fucking hit and miss, this is a matter of fact.
 
I have been taking 4mmc for over a year now, quit when the ban came in, to avoid dangerous street cuts like ket and god knows what other possible contraindications, seem to be left with short term memory loss, tooth enamel erosion, weight loss and a serious dent in my bank balance, never experienced any purple joints or pronounced vasoconstriction though, maybe thats why it dragged out so long...
 
Savagehenry said:
I have been taking 4mmc for over a year now, quit when the ban came in, to avoid dangerous street cuts like ket and god knows what other possible contraindications, seem to be left with short term memory loss, tooth enamel erosion, weight loss and a serious dent in my bank balance, never experienced any purple joints or pronounced vasoconstriction though, maybe thats why it dragged out so long...
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This is pretty much my situation also. I hope that the damage i have done to myself isn't permanent.
 
The amazing euphoria of the first 5 or 6 times I will never recapture, and that's the worst thing about it. I've never gone more than a week, for 5 months, without having at least half a gram. Over the past month it's usually been as frequent as every 2 or 3 days.
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If that's not addictive behaviour I must have a different dictionary
 
It's not physically addictive but it's by far the most addictive substance I've encountered in my life. More addictive than MDMA, Cocaine, Opiates, Benzos. I've tried the lot. Nothing has given me more of a desire to recapture the high.
 
i remember there was a rumor in the late 90's that if you had sex on ecstasy it would be the greatest pleasure humanly possible and you would never be able to attain that level again, so effectivly the rest of your life would be downhill. i had no interest in ecstasy or drugs in general but just that idea scared the shit out of me, of course it is not true. but on mephedrone - i actually felt that way, it was laughable.

im having so many bizarre side effects (perhaps the most severe of which is hypochondria) but the roof of my mouth is covered in agonizing cuts which will not heal, i have horrible throbbing sensations in my legs and feel generally shitty. i have also been not sleeping (not this was after only one dose of 100mg)
 
hamhurricane said:
against my best judgement (and for odd ethical reasons too involved for me to explain here) i decided to take a 100mg dose of mephedrone intranasally to evaluate its effects. before and after i ingested a smorgasbord of antioxidants including acetyl-l-carnitine, alpha lipoic acid, COQ10 and melatonin as well as 5mg tadalafil to combat the anticipated vasoconstriction.

the material was crystaline and smelly. i found it to be very MDA like, some visual distortion, warm "softening" effects and quasi-psychedelic ideation. it was highly entactogentic and sex on it was transcendently good, the only drug that has been better is LSD. otherwise it felt toxic and uninteresting. the euphoria was really brutal i could not even stand up - the idea of taking this in a crowded club or bar seems insane - i would have doubtlessly vomited. the only thing it had in common with cocaine was an unreal hangover, slept for 12 hours and felt unmotivated and depressed for an entire day. i would bet my life this stuff is having a significant effect on serotonin receptors. i hope the various prophylactic measures i took prevent any long term damage.

after seeing how strong this stuff is i feel much worse for the people who are consuming multiple grams in a night :(
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Are you sure it was mephedrone?! It's never come close to "transcendentally good" imho. Perhaps your "smorgasbord" of defences reacted in some unanticipated way to enhance the effect.
 
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