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[MEGA] Synthetic Cannabinoid Discussion - Take 4

thenightwatch said:
does orally ingested Anandamide actually make it into the CNS?
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If THC makes it, and Amandamide is mimicking it, then it should. And ever since I have been studying "Ocean Natural Products", people eating and liking Sushi seems to make more sense to me. The ocean is full of drugs (Ex: Check out 5-Br-DMT you can eat raw sponges and have a DMT trip).
 
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And AM404 is just part of the Tylenol breakdown, so if you eat a Tylenol before you eat some Roe it could help it hit.
 
They do look a lot different, so they probably would break down different in the stomach. Maybe make an extraction?
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800px-Anandamide_skeletal.svg.png
 
thenightwatch said:
even if you snorted pure anandamide, i'm not sure it would be able to cross the blood-brain barrier.
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Then take some Myrcene (Lemon Grass Extract or Mango juice) before you snort it!!!
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If you make Lemon grass BHO and put a dab on your weed, you do definitely get higher, I've tested it.
 
jeremysdemo said:
as possible non-lethal incapacitating agents in Edgewood Arsenal experiments.
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I've been finding a lot of drugs that are used as non-lethals that I personally think would be pretty fun to be on. Like, the whole idea on Batman of the drugs in the water being evaporated. That flower is a representation of Datura, and the "Military Microwave Weapon that Evaporates the water so the drug is in the air" is actually a representation of weapons grade Tropane type alkaloids that they have invented, like BZ and QNB. That shit is REAL.
 
thenightwatch said:
even if you snorted pure anandamide, i'm not sure it would be able to cross the blood-brain barrier.
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it's certainly small enough. 347.534698 Da

however it could be metabolized into something else when consumed.

when you read studies about anandamide in humans and rats it is usually endogenous anandamide the brain itself produces.
 
ShaggyFin said:
I've been finding a lot of drugs that are used as non-lethals that I personally think would be pretty fun to be on. Like, the whole idea on Batman of the drugs in the water being evaporated. That flower is a representation of Datura, and the "Military Microwave Weapon that Evaporates the water so the drug is in the air" is actually a representation of weapons grade Tropane type alkaloids that they have invented, like BZ and QNB. That shit is REAL.
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so much they are not releasing.

for all we know they already have the cure for old age, and genius pills for the masses!

only it is not in their best interest right now to let anyone have them!
 
jeremysdemo said:
it's certainly small enough. 347.534698 Da

however it could be metabolized into something else when consumed.

when you read studies about anandamide in humans and rats it is usually endogenous Anandamide the brain itself produces.
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I can't find anything about it.

@Everyone
Someone get some Lemon Grass alcohol extract and go to a Sushi restaurant, put the Extract in your drink, eat the Sea Urchin Roe, and tell us what happens. If it doesn't work, try again with a Tylenol (People die from Tylenol liver poisoning, so don't take Tylenol like it's the main course, just take 1). This could change some shit, because if people all over the country hear about it working (if it does) and everyone starts doing it, they will realize that legalizing weed is a really good idea.
 
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jeremysdemo said:
so much they are not releasing.

for all we know they already have the cure for old age, and genius pills for the masses!

only it is not in their best interest right now to let anyone have them!
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Provigil is kind of like a genius pill. They only let them prescribe it for Narcolepsy though.
And I have been studying a lot of Nicotine type alkaloids that look promising.
 
^actually I got prescribed it for ADD. All it did was make me nauseous and give me a caffeine like high that felt worse on my body than actual caffeine. Eugh.
 
Toz said:
^actually I got prescribed it for ADD. All it did was make me nauseous and give me a caffeine like high that felt worse on my body than actual caffeine. Eugh.
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If you actually have ADD, I think your doctor is just stupid. It's a drug to promote wakefulness, so you don't give that to someone who is already Hyperactive. Adderall and stuff works because it makes you tweak out, and want to pull apart the VCR or finish your homework, then burns you out so you can be chill.
 
^I live in Sweden, we have ONE available stimulant on prescription and that is methylphenidate. I can't even get a script for amphetamine because that requires a physician with a special license to prescribe it, of which there are a handful of in the entire country. I can't stand the effects of methylphenidate so there were not really alot of options to choose from. I don't think he is stupid, he just didn't have much to work with and tried to do what he could.

ADD is also the polar opposite of ADHD.

For such a developed country Sweden is seriously behind when it comes to medication. We have lots of really old medications being prescribed by even older doctors.

Either way I think we are getting side-tracked :)
 
jeremysdemo said:
well with several close friends all busted for noids in the last year I'd say my paranoia is extraordinarily manifesting itself into reality...

I offer everything anyone needs to not be on the wrong side of the law (by keeping up with the legislation) this just is not enough for some people!

yes the list of legal noids is a closely guarded secret, not for paranoia reasons tho! they are legal silly Help!

but for the reason that information such as this in the wrong hands can harm people, If I knew for sure someone was not going to share it, or if I knew them from Adam it would be different.
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Damn, I didn't realise they were busting people for noids. I haven't heard too much of it going on in the UK as of yet, but it's still pretty damn worrying. I guess it's very important to keep up on the latest legislation, and from now on I tend to just use one noid in a blend (if they ban one of the noids I use, that's the whole blend kaput. Oh yeah, I used the damiana, following your ratio; it's very peppery smelling and tasting so I had to add flavouring to it, though my CBD hasn't arrived yet and that's an international order.

On a side note, my neighbour got busted for weed, around 4 Oz but also a bag of my blend. They called him a "sly little bastard" for "not putting THC in there". Sheer incompetence.
 
thenightwatch said:
even if you snorted pure anandamide, i'm not sure it would be able to cross the blood-brain barrier.
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the endocannabinoid system of the body is used to regulate the nervous system, digestive system among other things.

it's not a wise idea to go messing with it without knowing what those adjustments will do.

as some synthetic cannabinoids are known analgesics some can actually decrease the bodies immune response.

the only way I could see anandamide leading to anything recreational is used in conjunction with an FAAH blocker.

even that has it's risk, could effect the brain adversely along with the peripheral.

just getting anandamide through the BBB is not enough as it rapidly breaks down and an unnatural rush of anandamide can cause all kinds of side effects.

take it from someone who has studied the effects of anandamide and other naturally occuring cannabinoids in chocolate, dosage is very crucial, a slight miscalculation can cause sever adverse effects, like nausea that last for hours, total loss of equilibrium for moments, heartburn, headaches and vomiting etc.

I don't know about anyone else but just feeling sick for a few hours is not my idea of a good time.
 
dopemegently said:
Damn, I didn't realise they were busting people for noids. I haven't heard too much of it going on in the UK as of yet, but it's still pretty damn worrying. I guess it's very important to keep up on the latest legislation, and from now on I tend to just use one noid in a blend (if they ban one of the noids I use, that's the whole blend kaput. Oh yeah, I used the damiana, following your ratio; it's very peppery smelling and tasting so I had to add flavouring to it, though my CBD hasn't arrived yet and that's an international order.

On a side note, my neighbour got busted for weed, around 4 Oz but also a bag of my blend. They called him a "sly little bastard" for "not putting THC in there". Sheer incompetence.
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yes the US is loosing it's major money maker for the justice system in many states (MJ) as it is being legalized, to make up for that loss of revenue they have preemptively targeted noids even before legislation is in place.
 
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