hx_
Bluelighter
Because in order to be ABSORBED, not metabolised your, body has to take it in somehow (eating it doesn't count, you can eat many types of seeds and you don't absorb em). As pure power this is very difficult: it won't dissolve in water and the limited amount of fat in your stomach means it wont really get absorbed through there.
However, if the compound is dissolved in oil, and that is taken up by the digestive tract, then bam; drugs in your bloodstream, down your portal vein, through your liver and whatever isn't metabolised then heads to your brain and makes you feel dizzy and floaty and hungry.
When you have "metabolised" something, the original chemical is broken down into constituent elements and compounds of these. If one of the metabolites was active (not in this case) then you'd get higher a significant time after you originally took the compound. If it were only the metabolites that were active then you'd have to wait a significant time to even feel anything.
http://en.wikipedia.org/wiki/First_pass_effect
"Alternative routes of administration like suppository, intravenous, intramuscular, inhalational aerosol and sublingual avoid the first-pass effect because they allow drugs to be absorbed directly into the systemic circulation."
Inhalational aerosol is pretty analagous to smoking.
However, if the compound is dissolved in oil, and that is taken up by the digestive tract, then bam; drugs in your bloodstream, down your portal vein, through your liver and whatever isn't metabolised then heads to your brain and makes you feel dizzy and floaty and hungry.
When you have "metabolised" something, the original chemical is broken down into constituent elements and compounds of these. If one of the metabolites was active (not in this case) then you'd get higher a significant time after you originally took the compound. If it were only the metabolites that were active then you'd have to wait a significant time to even feel anything.
http://en.wikipedia.org/wiki/First_pass_effect
"Alternative routes of administration like suppository, intravenous, intramuscular, inhalational aerosol and sublingual avoid the first-pass effect because they allow drugs to be absorbed directly into the systemic circulation."
Inhalational aerosol is pretty analagous to smoking.
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