• CD Moderators: someguyontheinternet
  • Cannabis Discussion Welcome Guest
    Posting Rules Bluelight Rules

[MEGA] Synthetic Cannabinoid Discussion - Take 3

Status
Not open for further replies.
Because in order to be ABSORBED, not metabolised your, body has to take it in somehow (eating it doesn't count, you can eat many types of seeds and you don't absorb em). As pure power this is very difficult: it won't dissolve in water and the limited amount of fat in your stomach means it wont really get absorbed through there.

However, if the compound is dissolved in oil, and that is taken up by the digestive tract, then bam; drugs in your bloodstream, down your portal vein, through your liver and whatever isn't metabolised then heads to your brain and makes you feel dizzy and floaty and hungry.


When you have "metabolised" something, the original chemical is broken down into constituent elements and compounds of these. If one of the metabolites was active (not in this case) then you'd get higher a significant time after you originally took the compound. If it were only the metabolites that were active then you'd have to wait a significant time to even feel anything.

http://en.wikipedia.org/wiki/First_pass_effect

"Alternative routes of administration like suppository, intravenous, intramuscular, inhalational aerosol and sublingual avoid the first-pass effect because they allow drugs to be absorbed directly into the systemic circulation."

Inhalational aerosol is pretty analagous to smoking.
 
Last edited:
HAHAHAHA - On the floor - cold sweats!!! J/K!!!!!

I didn't sleep to good, was a bit bitchy, got pissed off a bit easier. Nothing major, but I expected nothing I guess, lol. Not to mention the REALLY wanting to smoke it. I think it was all in my head but I didn't like it...lol. Who would though right! lol. Going from daily to nothing was weird. Not like quitting cigarettes though of course (I quit that years ago and now THAT sucked).


Some GREAT views on the addiction level of the pure chems. If it is simply based on person to person - I better watch out - I know I have an addictive personality. lol


The addiction level depends on how much willpower you have.

Also, once on it, don't fall for this. "Ill definitely get that done soon, or definitely stop smoking this soon." When |Something| happens, that's when Ill do it. That something for me ended up being either: nearly getting fired, running out or going on holiday and having the worst time ever.


Biggest tip I have, don't buy more than a few g's at once, my real problems started when I got a 50g bag!



Oh btw, it aint all it your head. It's in all the places where your body has CB receptors, it's killed a load of them off because it didn't think the constant "CANNABOID AGOISE" messages were normal.

Natural homeostatis tried to reduce how many cannaboid molecules could signal your nervous system (yes, all of it), and now the natural ones like anadimide are having a hard time getting their message accross.


Best of luck, and get back to the real ganja.
 
Last edited:
Oh btw, it aint all it your head. It's in all the places where your body has CB receptors, it's killed a load of them off because it didn't think the constant "CANNABOID AGOISE" messages were normal.

Natural homeostatis tried to reduce how many cannaboid molecules could signal your nervous system (yes, all of it), and now the natural ones like anadimide are having a hard time getting their message accross.

IT KILLED THEM OFF!!!!!???? They are going to regrow right??? or do i have brain damage now?
 
No CB receptors were killed off - some may have temporarily downregulated. Talk about a "ridiculously stupid disinformation warning" 8)
 
HAHAHAHA - On the floor - cold sweats!!! J/K!!!!!

I didn't sleep to good, was a bit bitchy, got pissed off a bit easier. Nothing major, but I expected nothing I guess, lol. Not to mention the REALLY wanting to smoke it. I think it was all in my head but I didn't like it...lol. Who would though right! lol. Going from daily to nothing was weird. Not like quitting cigarettes though of course (I quit that years ago and now THAT sucked).


Some GREAT views on the addiction level of the pure chems. If it is simply based on person to person - I better watch out - I know I have an addictive personality. lol

I get what you're saying. I feel like "Cannabinoid withdrawls" are just like losing a girlfriend. At first it's like "how did I live day to day before this" then eventually, you just stop thinking about it... I think the reason we still "think" about it is because it is in our systems still, for at least 30 days.

And that made me think of something kinda funny, that may teach some stoners something they didn't know. I was on probation and I STOPPED SMOKING, I was smoking NO weed. For 31 days I was clean... On that 31st day my friend at school told me "My parents are going to drug test me, what do I do?"... So I pissed in a water bottle for him... He took my piss home, and FAILED the piss test.
Most people seem to think your system is clean after 30 days, and that is NOT true. If you smoke everyday, and most of the day... You've got like 3 months of dirty piss, no matter how much you drink water or sweat.

And (in my experience, meaning I DO NOT suggest this) you can smoke while you are on probation for the first month, because your piss is still dirty for a while anyways. They test levels of stuff on probation test (that way they can make sure it's not synthetic piss, or from the opposite gender of yourself), so if you smoke less weed your first month of probation than you did BEFORE probation, you might be able to get away with pissing dirty, since your levels will be lowering. Some PO's don't even piss test until 3 months in, just to make sure (it happened to me, that's why I no longer live in Texas).
 
And that made me think of something kinda funny, that may teach some stoners something they didn't know. I was on probation and I STOPPED SMOKING, I was smoking NO weed. For 31 days I was clean... On that 31st day my friend at school told me "My parents are going to drug test me, what do I do?"... So I pissed in a water bottle for him... He took my piss home, and FAILED the piss test.
Most people seem to think your system is clean after 30 days, and that is NOT true. If you smoke everyday, and most of the day... You've got like 3 months of dirty piss, no matter how much you drink water or sweat.

I only had a week notice for the piss test I asked around some people in the trades what they recommended and I went to the head shop and spoke to them and took the recommended appropriate drink/cleanse.masking agent - whatever you want to call it (you have to have stopped smoking pot for at least 2 days or longer and there are strick instructions on timing and amount of fluids - but it worked - I passed the test - so did my friend that was ina similar situation - should always keep one of those on hand.

That's why I started smoking the synthetics - no worry of failing a stupid drug test.
 
I'm not worried about drug tests :) But true shit, REAL Cannabis is the only thing that is going to show up.
I just wanted to share some experience that I was reminded of by what I replied to.

:-) That is a good story!!! I would have thought for sure your piss would have been clean after 30 days too! lol.

Question for everyone?? Does anyone find that weed kinda sucks after smoking synthetic for a while?? I smoked some real bud with a buddy last night(it was random and I'm no too worried about piss test at this point), and it wasn't all that good. Tasted GREAT! Smelled GREAT - but the high was a let down. It was extremely good bud. My friends were REALLY cooked, but it just wasn't hitting me. Nothing as high as most of the synthetic (even though they were blends and yes - boo on me for smoking the blends) got me.

There is 1 local chain of head shops here that doesn't sell blends, herbal incense any of the stuff they have a big sign saying they don't sell it and don't bothing asking where to buy it as they don't know and wouldn't tell anyway. When you speak with the people that work there they have all sorts of ideas about synthetic canniboids. They told me that when you smoke them regularly that eventually your body won't respond to weed and weed won't get you high any more - ever... I didn't really believe them - they are a different type of group of hippies that work there (for that chain).

One of the other big chain head shops here (the one I frequent) sells a variety of the blends, but they claim that they only sell ones that they have met the producers and that these guys have lab coats, etc.... blah blah blah, I don't really believe them either - but they do sell a lot of selection by the same maker (diff types same company)... And they disagree with the other head shop.

Then there is a few other head shops that sell random blends I wouldn't dare buy, these shops just sell cheap quality everything.... and the packaging just looks scary enough!!! Probably made in the back room!!!!

And they say EVERYTHING is awesome - but I think they are fried in the brain and they really just want $$$
 
Idk if this matters to anyone but this IS the synthetic cannabinoid discussion sooo I guess I should post this here? I'm kinda new. but anyways... I got some of the newest cannabinoid out there, which is PB22, delivered to me. 99.8% purity (quality assured). by college chemistry lab ;) (professor is family) I would like to post my experience with this substance. first of all, I HAVE A VERY HIGH CANNABINOID TOLERANCE. I have experience with everything from the good ol' JWH's and AM's to the URB (terrible) and the newly outlawed UR-144, 5f-ur-144, akb48, 5f-akb48, sts-135, the MAM-2201 and EAM-2201, AB-001, etc. Upon opening the vial with the fine purely white crystalline/chalky like powder, I did not notice any distinct odor. Now for my average home purity test, the mind test. I take a cigarette, cut more than half of the filter off, empty some of the tobacco out of the end, and barely dip my cigarette in the powder till there's barely enough to cover my tobacco to where you can still see tobacco that's been slightly saturated in this fine powder. I eyeballed it, which I do not recommend ANYONE do, but I have done this stuff for a long time and pretty well know how to eyeball a couple milligrams, believe it or not. I would say i eyeballed around 10-15mgs. Anyway, I hold the cig up and light it and hold the lighter to it like I'm smoking salvia divinorum or something. until the end of the cig catches fire, blow out the flame, and toke again, slowly. Almost instantly It reminds me of ur-144 and 5f the taste is almost the exact same. the EXACT SAME. I get a chill down my spine, an enjoyable one at that, and when I finish the cigarette completely, the high is slowly creeping on me. and it peaked me at an amazing high as a fucking kite feeling in about 5-10 minutes upon dosing. very clean feeling buzz, very pot-like but a little more intense. lasted about 30-45 mins. average cannabinoid high duration, sadly.. I bet if you're the type that loves the psychedelic 'noid trips, you could ingest more and not get the "I'm dying" feeling. but that all was just my 2 cents. hope that helps some understand this new chemical a little more. Sorry I couldn't give any scientific information.. :\

____________
EDIT:

I would post this experience on a specific PB22 discussion but I couldnt find one. and on drugs forum they wouldnt let me post because my account was so new.
 
Last edited:
Idk if this matters to anyone but this IS the synthetic cannabinoid discussion sooo I guess I should post this here? I'm kinda new. but anyways... I got some of the newest cannabinoid out there, which is PB22, delivered to me. 99.8% purity (quality assured). by college chemistry lab ;) (professor is family) I would like to post my experience with this substance. first of all, I HAVE A VERY HIGH CANNABINOID TOLERANCE. I have experience with everything from the good ol' JWH's and AM's to the URB (terrible) and the newly outlawed UR-144, 5f-ur-144, akb48, 5f-akb48, sts-135, the MAM-2201 and EAM-2201, AB-001, etc. Upon opening the vial with the fine purely white crystalline/chalky like powder, I did not notice any distinct odor. Now for my average home purity test, the mind test. I take a cigarette, cut more than half of the filter off, empty some of the tobacco out of the end, and barely dip my cigarette in the powder till there's barely enough to cover my tobacco to where you can still see tobacco that's been slightly saturated in this fine powder. I eyeballed it, which I do not recommend ANYONE do, but I have done this stuff for a long time and pretty well know how to eyeball a couple milligrams, believe it or not. I would say i eyeballed around 10-15mgs. Anyway, I hold the cig up and light it and hold the lighter to it like I'm smoking salvia divinorum or something. until the end of the cig catches fire, blow out the flame, and toke again, slowly. Almost instantly It reminds me of ur-144 and 5f the taste is almost the exact same. the EXACT SAME. I get a chill down my spine, an enjoyable one at that, and when I finish the cigarette completely, the high is slowly creeping on me. and it peaked me at an amazing high as a fucking kite feeling in about 5-10 minutes upon dosing. very clean feeling buzz, very pot-like but a little more intense. lasted about 30-45 mins. average cannabinoid high duration, sadly.. I bet if you're the type that loves the psychedelic 'noid trips, you could ingest more and not get the "I'm dying" feeling. but that all was just my 2 cents. hope that helps some understand this new chemical a little more. Sorry I couldn't give any scientific information.. :\

____________
EDIT:

I would post this experience on a specific PB22 discussion but I couldnt find one. and on drugs forum they wouldnt let me post because my account was so new.

Paragraphs, actual chemical name etc etc?




IUPAC: Quinolin-8-yl 1-pentyl-1H-indole-3-carboxylate / 1H-Indole-3-carboxylic acid, 1-pentyl-, 8-quinolinyl ester (not sure which is best)

CAS number: 1400742-17-7

Formula: C23H22N2O2

from df


Seems like its being pushed as russian legal.
 
I quite enjoyed their post to be fair.

thanks. lol, I was trying to be as detailed as I could but I was coming down off the shit. lol. hard to concentrate. it has somewhat dissociative properties at higher doses.

Am I an addict if I smoked a whole gram of this new chemical in a day? starting from when my mail ran at like 1:30 PM to finishing the bag at about 6 PM? i think so. lol. it doesnt have the potential to last quite as long as the 5f-ur-144 that shit lasted me for like a week or two. but every time i smoked it, i was trippin out having this feeling i had a bug crawling around in my mouth that was saturated in spit. pretty gross. (this was with high doses of 5f-ur-144) but i only got that with an extremely high dose. i know it sounds crazy. and when i'd spit of course there'd be no bug. id even feel the bug biting my tongue. weird shit. i miss full cb1 agonists. :'(
wish i could find a vendor for am-2201 or MAM-2201 that would ship to the US but most that i find take that shit serious, unfortunately.
 
Shaggyfin, MN-18, EAM-2201, and 5F-AKB48 are "like" JWH classics.


As far as that sensationalist story about the brain damaged girl, we have no idea what she was smoking, or what other drugs she was doing, or if she had pre-existing problems.

There's only two scenarios:

A. The "gas station blends" she smoked had some kind of nasty herbs as a base, or the 'noids they were laced with had some terrible impurity.

or

B. She had some pre-existing condition, or was abusing other, more dangerous drugs, and her parents simply didn't know.

I've been using synthetics for around 5 years now, and I'm as healthy as a horse. Keep in mind, I *never* use store-bought blends...I've heard some speculation from fellow researchers that some of the newer cannabinoids may put a little extra strain on the kidneys, if your body is susceptible to that type of thing and you're using a lot, but STROKES?! Unheard of - there's definitely something else going on, and it sucks because it's giving synthetics a really bad name.

EDIT: Logan1314, JWH-073 is a "waste product"? You get my "bullshit of the day" award, congrats...I'm curious though, how did you come to that conclusion?

I could swear that a mod said something like that WAAYYY earlier in this thread, I might be wrong though. Doesn't the production of some of the main JWH's produce some waste products that stores would use in their blends?

thanks. lol, I was trying to be as detailed as I could but I was coming down off the shit. lol. hard to concentrate. it has somewhat dissociative properties at higher doses.

Am I an addict if I smoked a whole gram of this new chemical in a day? starting from when my mail ran at like 1:30 PM to finishing the bag at about 6 PM? i think so. lol. it doesnt have the potential to last quite as long as the 5f-ur-144 that shit lasted me for like a week or two. but every time i smoked it, i was trippin out having this feeling i had a bug crawling around in my mouth that was saturated in spit. pretty gross. (this was with high doses of 5f-ur-144) but i only got that with an extremely high dose. i know it sounds crazy. and when i'd spit of course there'd be no bug. id even feel the bug biting my tongue. weird shit. i miss full cb1 agonists. :'(
wish i could find a vendor for am-2201 or MAM-2201 that would ship to the US but most that i find take that shit serious, unfortunately.

Got the EXACT SAME THING. I was convinced I drank some water infected with bacteria and bugs were spawning in my throat and mouth!!!!
 
Last edited by a moderator:
I hate the feeling 5f-ur-144 gives my mouth/throat with high doses.

5f-pb-22 kind of reminds me of ur-144 with a bit of akb48. It's more of a "trippy" noid and can get dissociative in high dosage. I wish there was more data on these pb's
 
I could swear that a mod said something like that WAAYYY earlier in this thread, I might be wrong though. Doesn't the production of some of the main JWH's produce some waste products that stores would use in their blends?


No. Sometimes, some really messy batches that are too difficult to thoroughly clean, but still contain a decent amount of active ingredients (as well as unreacted precursors and byproducts) have been sold off to unscrupulous blend manufacturers at a discount - but that could happen with any cannabinoid that's had a careless synthesis, there's nothing special about JWH-073 in that regard.
 
Got some AM-2201.

This is a long muddled thread so...

Opinions please? :)
 
Got some AM-2201.

This is a long muddled thread so...

Opinions please? :)

After a few days you're going to feel like you are taking retard medicine. Like if someone were to ask you "Are you taking retard pills" you would say "Yes". And my friend had a convulsive seizure on it, so watch out for that too...
 
Status
Not open for further replies.
Top