Notes on MDPV use/abuse and ROA's
Please don't touch this shit with a lighter from underneath
Particularly if you're not good at it/careless... when it catches fire, you'll inhale a lungful of transistor-radio-tasting smoke and go flying backwards at the same time

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Smoking MDPV is weird shit, lemme tell ya... there have been times have it where I've had a lot around, ran out of lighter fluid and started hitting off the kitchen stove burner in large amounts. Followed by wandering the house in a state of delerium for a couple hours, not knowing where or who I was. If that doesn't sound like fun, I agree... don't get started with smoking it. For all intents and purposes, it is crack.
Not that large amounts via other ROA's (such as snorting) is any better. You can just as easily dip into dopamine psychosis through too-frequent intranasal dosing. And you may not know any better if you start hallucinating your hands swelling up, or your face turning grey/purple, or see your feet go all red white and blue like the American flag... you'll think you're dying of MDPV-related causes.
That's one thing medics are damn good for, BTW... they can tell you if your body is disintegrating before your eyes, or if you're only hallucinating it. Chances are all that's real are the cracked black scab on your lip, the trash / clothing / debris scattered around the house, and your growing notoriety amongst local area paramedics. You can also easily lose a lot of weight and lapse into a chronic, intractable state of sleep deprivation. The comedown/crash can get so difficult that dying would be easier, and certainly far less torturous.
That said, it is an astonishingly "mental" drug. Luckily, most of what happens /can happen with MDPV is in your mind, thus can be re-thought and changed, provided you eat, sleep and move about the way you're supposed to. How far can one's body be pushed in terms of overstimulation, inactivity, malnutrition and sleep deprivation? F*ck if I know, but I'm sure there are limits.
Do something really stupid like hard alcohol (or opiates/benzos) very heavily and rail big lines of MDPV, and you're dead.
http://www.ksdk.com/news/article/256566/3/Woman-dies-after-bath-salts-overdose-in-Alton
If you're going to be irresponsible, do it responsibly

. On Bluelight, they call that harm reduction.
My take on MDPV ROA's (routes of administration):
The major difference in the various ROA's, IME, is how quickly the effects come on (which equates to 'rush', and also to potential addictiveness).
The quickest ROA's are smoking and slamming/IV'ing, and that applies to most drugs. You can have a large amount hit you very suddenly, thus feeling a rush. It will also be more addictive via these ROA's, both in the short/binge and long terms.
Smoking is wasteful -- it burns a lot of drug that never gets into your system, even if you do it carefully. You'll go through your supply VERY fast when smoking it. It also subjects you to toxic byproducts, which are *not* a myth... you'll taste them from time to time and gag, I guarantee it. However, it's the quickest/most potent ("rush-iest") ROA, short of IV'ing... you can get large amounts of substance into your body very quickly. Watch it, as too many big hits too close together can send you into panic/anxiety, delerium or psychosis.
IV'ing (slamming) is both the most conservative (amount-wise) and the fastest-acting (rush/high-wise). A purist will insist on this method. However, it is the riskiest route of administration, as it's never safe to put anything directly into your bloodstream. The bloodstream was not designed to have anything introduced into it directly, and IV'ing is risky even under sterile medical conditions, with the substance administered by a physician. You can't take it back, either... once it's in, it's in.
Intranasal and rectal are also pretty quick -- in particular, intranasal (snorting) is probably the least wasteful way to use the drug, short of IV'ing.... your supply of MDPV will likely last the longest when you use it intranasally. Dissolving it in some water first and administering it via a vaporizer can be helpful in terms of exact dosing, as long as you don't dissolve large amounts (keep it to 50-100mg at a time max), since MDPV tends to break down fairly fast in solution. The drug will be absorbed rapidly through the nasal mucosa, and what isn't will be swallowed and absorbed in the stomach/intestines.
Rectal (plugging) is interesting, and can be a convenient one-off dosing method, provided you're comfortable with it. But it's really no better than intranasal, IME, and probably not as good. You don't need to bypass first-pass metabolism, particularly if you're using intranasally. It can also be potentially wasteful, depending on the condition of the inside of your rectum.
Oral administration (eating it) is often the worst ROA, despite its popularity. Not only does it take a long time to come on, but can be wasteful due to incomplete oral bioavailability. However, the resulting high can be the most stable and predictable, with the fewest ups and downs.
In short -- If "big rushes" are the most important, I'd go for smoking/vaping. If conserving product is the most important, I'd go for snorting/intranasal. If both are the most important, I'd go for IV'ing/slamming.
My take on rapidity of effects:
Most stim users seem to equate euphoria with a sudden rush (a large amount coming on rapidly), but that isn't the only type of euphoria to be had from stims. A gradual, sustained, high blood level can feel like a completely different drug. I recommend experimenting with dosing
very small and very often, particularly if you like the sexual side of stimulants. IME, roller-coaster rushing is not as conducive to them as a steady, strong, intense high that one has fully adapted to and that presents no surprises. Then you can pull out the porn and enjoy

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Peace...