It generally goes against my principles to tell people how to get high, but after three glasses of wine here goes:
Test your pills. Know how strong they are - find this out from some trusted friends or acquaintances who are familiar with E. Have them help you plan a dose that should get you good and high.
On the day you want to roll, eat a good breakfast and lunch but don't eat for at least 6 hours before you take the E because the idea is to take it on an empty stomach. Crush up your E and pour it into an energy drink or some water and drink the whole thing or else just chew the E and then chase it with water or an energy drink. I think the first option is better because E is horribly bitter and nasty tasting and if you chew it then it gets stuck in your teeth and that's totally shitty.
After you down the E then just go chat with friends or get busy on the dance floor and try to forget you took the stuff. After about 20 to 40 minutes you probably will notice that your stomach tightens a little bit, you kind of get a feeling like butterflies and that you'll get these warm little surges where you all of a sudden feel yourself starting to smile for no reason but they don't last very long and then all of a sudden WHOOOOOOSH!!!!!! you'll get this wave of sheer euphoria and pleasure that rolls up from the pit of your stomach and travels up your spine like a lightning bolt and in that millisecond the world will become a place of magic and wonder beyond your wildest dreams. The first time you get a real E rush can be like being strapped to the front of a high speed train - equally terrifying and exhilirating with you thinking the rush will never stop - it can be insanely intense.
In the moment when E hits, I'd recommend you have somebody close by that you can grab onto and give a hug because you'll find out what a warm connection with someone else can feel like and you just may be left whimpering with pleasure while the rush comes.