Yes, another Lyrica thread, sorry guys.
Because of the speedy (yet calm and blissful) Lyrica's effects, I was wondering if some Clonidine (also known as Catapres) would help to stop the euphoria/hungry/excitement (aka speedy effects) of Lyrica.
"Clonidine has been investigated and prescribed first as an antihypertensive drug in the 1950s. It has found new uses later, including treatment of some types of neuropathic pain, opioid detoxification, sleep hyperhidrosis, and as veterinary anaesthetic drug."
Clonidine is the best drug to come down I have ever tried, with some benzos, like 0.5 mg Alprazlam or 5 mg Diazepam, it works like a charm, and keep in mind that I have a heavy benzo tolerance.
A key point of Clonidine is that it works in the opioid receptors
"It is concluded that the analgesic response to clonidine involves activation of central μ-opioid receptors in both SHR and SD rats, possibly by an endogenous opioid released by clonidine."
So, would mixing a low Lyrica dose with Naproxen (to increase bioavailability, blah blah blah) and Clonidine worth it?
Thanks in advance.
Because of the speedy (yet calm and blissful) Lyrica's effects, I was wondering if some Clonidine (also known as Catapres) would help to stop the euphoria/hungry/excitement (aka speedy effects) of Lyrica.
"Clonidine has been investigated and prescribed first as an antihypertensive drug in the 1950s. It has found new uses later, including treatment of some types of neuropathic pain, opioid detoxification, sleep hyperhidrosis, and as veterinary anaesthetic drug."
Clonidine is the best drug to come down I have ever tried, with some benzos, like 0.5 mg Alprazlam or 5 mg Diazepam, it works like a charm, and keep in mind that I have a heavy benzo tolerance.
A key point of Clonidine is that it works in the opioid receptors
"It is concluded that the analgesic response to clonidine involves activation of central μ-opioid receptors in both SHR and SD rats, possibly by an endogenous opioid released by clonidine."
So, would mixing a low Lyrica dose with Naproxen (to increase bioavailability, blah blah blah) and Clonidine worth it?
Thanks in advance.